CDE Detailed Report
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| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C12028 | Written Verbal Fluency Test (WVFT) - copy word fast possible duration | WVFTCopyWordFastPossDur | Duration required by the participant/subject to copy the legitimate words from both the intial-S list and the 4-letter initial-C list as fast as possible | Duration required by the participant/subject to copy the legitimate words from both the initial-S list and the 4-letter initial-C list as fast as possible | Scoring | Numeric Values |
Following a delay (which reduces fatigue), the patient is timed as they copy the words they previously generated as fast as possible. |
Abrahams S., Leigh P.N., Harvey A., Vythelingum G.N., Grise D., Goldstein L.H. (2000). Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38:734-47. Abrahams S., Goldstein L.H., Al-Chalabi A., Pickering A., Morris R.G., Passingham R.E., Brooks D.J. and Leigh P.N. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 62:464-72. Abrahams S., Goldstein L.H., Simmons A., Brammer M.J., Williams S.C.R., Giampietro V. and Leigh P.N. (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127:1507-17. Abrahams S., Goldstein L.H., Suckling J., Ng V., Simmons A., Giampietro V., Atkins L., Williams S.C.R. and Leigh, P.N. (2005a). Fronto-temporal white matter changes in patients with amyotrophic lateral sclerosis. Journal of Neurology, 252:321-31. Abrahams S., Goldstein L.H. and Leigh P.N. (2005b). Cognitive change in amyotrophic lateral sclerosis: a prospective study. Neurology, 64:1222-26. | Adult;Pediatric | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Written Verbal Fluency Test | [php] | [php_1] |
Free-Form Entry |
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| C12029 | Written Verbal Fluency Test (WVFT) - index value | WVFTIndexVal | Value of the Written Verbal Fluency Index, calculated by subtracting the time taken to copy the words from 9 minutes, then dividing the resulting time by the number of legitimate words | Value of the Written Verbal Fluency Index, calculated by subtracting the time taken to copy the words from 9 minutes, then dividing the resulting time by the number of legitimate words | Scoring | Numeric Values |
The patient is timed as they copy the words they previously generated as fast as possible, from which a Written Verbal Fluency Index is calculated. This consists of an estimate of the average time to 'think' of each word [(the time allowed for the test: 9 minutes minus the time taken to copy the words], divided by the total number of correct words]. |
Abrahams S., Leigh P.N., Harvey A., Vythelingum G.N., Grise D., Goldstein L.H. (2000). Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38:734-47. Abrahams S., Goldstein L.H., Al-Chalabi A., Pickering A., Morris R.G., Passingham R.E., Brooks D.J. and Leigh P.N. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 62:464-72. Abrahams S., Goldstein L.H., Simmons A., Brammer M.J., Williams S.C.R., Giampietro V. and Leigh P.N. (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127:1507-17. Abrahams S., Goldstein L.H., Suckling J., Ng V., Simmons A., Giampietro V., Atkins L., Williams S.C.R. and Leigh, P.N. (2005a). Fronto-temporal white matter changes in patients with amyotrophic lateral sclerosis. Journal of Neurology, 252:321-31. Abrahams S., Goldstein L.H. and Leigh P.N. (2005b). Cognitive change in amyotrophic lateral sclerosis: a prospective study. Neurology, 64:1222-26. | Adult;Pediatric | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Written Verbal Fluency Test | [php] | [php_1] |
Free-Form Entry |
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| C12025 | Written Verbal Fluency Test (WVFT) - write letter S word five minute count | WVFTWriteLtrSWord5MinCt | Count of legitimate words beginning with the letter S written by the participant/subject in 5 minutes | Count of legitimate words beginning with the letter S written by the participant/subject in 5 minutes | Scoring | Numeric Values |
Write as many words as possible beginning with the letter S in 5 minutes. |
Abrahams S., Leigh P.N., Harvey A., Vythelingum G.N., Grise D., Goldstein L.H. (2000). Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38:734-47. Abrahams S., Goldstein L.H., Al-Chalabi A., Pickering A., Morris R.G., Passingham R.E., Brooks D.J. and Leigh P.N. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 62:464-72. Abrahams S., Goldstein L.H., Simmons A., Brammer M.J., Williams S.C.R., Giampietro V. and Leigh P.N. (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127:1507-17. Abrahams S., Goldstein L.H., Suckling J., Ng V., Simmons A., Giampietro V., Atkins L., Williams S.C.R. and Leigh, P.N. (2005a). Fronto-temporal white matter changes in patients with amyotrophic lateral sclerosis. Journal of Neurology, 252:321-31. Abrahams S., Goldstein L.H. and Leigh P.N. (2005b). Cognitive change in amyotrophic lateral sclerosis: a prospective study. Neurology, 64:1222-26. | Adult;Pediatric | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Written Verbal Fluency Test | [php] | [php_1] |
Free-Form Entry |
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| C12026 | Written Verbal Fluency Test (WVFT) - write four letter C word four minute count | WVFTWrite4LtrCWord4MinCt | Count of legitimate words exactly 4 letters long and beginning with the letter C that the participant/subject was able to write in 4 minutes | Count of legitimate words exactly 4 letters long and beginning with the letter C that the participant/subject was able to write in 4 minutes | Scoring | Numeric Values |
Write as many words consisting of four letters only beginning with the letter C in four minutes. |
Abrahams S, Leigh PN, Harvey A, Vythelingum GN, Grise D, Goldstein LH. Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia 38(2000):734-747. Abrahams, S., Goldstein, LH., Al-Chalabi, A., Pickering, A., Morris, RG., Passingham, RE., Brooks, DJ. and Leigh PN. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 62, 464-472. Abrahams, S., Goldstein, L.H., Simmons, A., Brammer, M. J., Williams, S. C. R. Giampietro, V. and Leigh, P.N (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127, 1507 - 1517. Abrahams, S., Goldstein, L.H., Suckling, J., Ng, V., Simmons, A., Giampietro, V. Atkins, L., Williams, S.C.R. and Leigh, P.N.. (2005a) Fronto-temporal white matter changes in patients with amyotrophic lateral sclerosis. Journal of Neurology. 252, 321-331. Abrahams, S., Goldstein, L.H. and Leigh, P.N. (2005b) Cognitive change in amyotrophic lateral sclerosis: a prospective study. Neurology, 64 1222-1226 | Adult;Pediatric | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Written Verbal Fluency Test | [php] | [php_1] |
Free-Form Entry |
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| C12027 | Written Verbal Fluency Test (WVFT) - copy previous word rapid text | WVFTCopyPrevWordRapidTxt | Text of previously generated words copied by the participant/subject as fast as possible as part of Written Verbal Fluency Test | Text of previously generated words copied by the participant/subject as fast as possible as part of Written Verbal Fluency Test | The participant/subject copies the words previously generated as fast as possible | Alphanumeric |
No additional instructions |
Abrahams S., Leigh P.N., Harvey A., Vythelingum G.N., Grise D., Goldstein L.H. (2000). Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia, 38:734-47. Abrahams S., Goldstein L.H., Al-Chalabi A., Pickering A., Morris R.G., Passingham R.E., Brooks D.J. and Leigh P.N. (1997). Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 62:464-72. Abrahams S., Goldstein L.H., Simmons A., Brammer M.J., Williams S.C.R., Giampietro V. and Leigh P.N. (2004). Word retrieval in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study. Brain, 127:1507-17. Abrahams S., Goldstein L.H., Suckling J., Ng V., Simmons A., Giampietro V., Atkins L., Williams S.C.R. and Leigh, P.N. (2005a). Fronto-temporal white matter changes in patients with amyotrophic lateral sclerosis. Journal of Neurology, 252:321-31. Abrahams S., Goldstein L.H. and Leigh P.N. (2005b). Cognitive change in amyotrophic lateral sclerosis: a prospective study. Neurology, 64:1222-26. | Adult;Pediatric | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Written Verbal Fluency Test | [php] | [php_1] | 255 |
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