CDE Detailed Report

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CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C54951 Blood glucose upper threshold value BldGlucoseUpThreshldVal Value of blood glucose upper threshold prompting treatment Value of blood glucose upper threshold prompting treatment Glucose control: Upper limit Numeric Values

Glucose control – upper/lower limit: Upper/lower value of blood sugar levels that prompt treatment (Units will depend on country of origin). Use 'Blood glucose unit of measure' to capture units.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1]

Free-Form Entry

C54930 Systolic blood pressure augmentation measurement SystlcBldPrssrAugmentatnMeasr Measurement of systolic blood pressure augmentation Measurement of systolic blood pressure augmentation Blood pressure augmentation (mmHg): Systolic blood pressure (SBP) Numeric Values

Blood pressure augmentation goal: Blood pressure augmentation goal (MAP or systole) beyond routine upper limit of blood pressure for prevention or treatment of delayed cerebral ischemia

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:35:33.0 ICU Therapies [php] [php_1]

Free-Form Entry

Millimeters of mercury
C54941 Blood glucose unit of measure BloodGlucoseUOM Unit of measure for reporting blood glucose values Unit of measure for reporting blood glucose values Glucose control: Upper/Lower limit: Alphanumeric

Units will depend on country of origin

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:15:56.0 ICU Therapies [php] [php_1] 50

Free-Form Entry

C54952 Intracranial hypertension cerebral edema osmotherapy specify text IntcnlHytnsCblEdmOsmthpySpcTxt The free-text field related to 'Intracranial hypertension cerebral edema osmotherapy indicator' for specifying the osmotherapy administered The free-text field related to 'Intracranial hypertension cerebral edema osmotherapy indicator' for specifying the osmotherapy administered Osmotherapy for intracranial hypertension or cerebral edema: Yes, specify Alphanumeric

Osmotherapy: Any use of osmotherapy (mannitol, hypertonic saline or others) for treatment of intracranial hypertension or brain edema

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:47:50.0 ICU Therapies [php] [php_1] 255

Free-Form Entry

C54931 Hemodynamic therapy indicator HemodynamicTherapyInd Indicator of whether hemodynamic therapy is being given to the subject/participant Indicator of whether hemodynamic therapy is being given to the subject/participant Hemodynamic therapy Yes, specify;No Yes, specify;No Alphanumeric

Hemodynamic therapy – general: Any goal-directed intervention aimed to influence cardiac output or volume status or blood pressure or any combination

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:41:34.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54942 Sodium level lower threshold value SodiumLvlLoThreshldVal Value of lower sodium threshold level prompting treatment Value of lower sodium threshold level prompting treatment Sodium management: Lower Limit Numeric Values

Sodium management - upper/lower limit: Upper/lower value of sodium levels that prompt treatment (Units will depend on country of origin). Use 'Sodium unit of measure' to capture units.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1]

Free-Form Entry

C54932 Hemodynamic therapy specify text HemodynamicTherapySpecifyTxt The free-text field related to 'Hemodynamic therapy indicator' for specifying the hemodynamic therapy being given The free-text field related to 'Hemodynamic therapy indicator' for specifying the hemodynamic therapy being given Hemodynamic therapy: Yes, specify Alphanumeric

Hemodynamic therapy – general: Any goal-directed intervention aimed to influence cardiac output or volume status or blood pressure or any combination

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:44:36.0 ICU Therapies [php] [php_1] 500

Free-Form Entry

C54943 Sodium level unit of measure SodiumLvlUOM Unit of measure for recording sodium level Unit of measure for recording sodium level Sodium management: Upper/Lower Limit Alphanumeric

Units will depend on country of origin.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1] 50

Free-Form Entry

C54933 Hemodynamic augmentation indicator HemodynamicAugmentatnInd Indicator of whether hemodynamic augmentation is being given to the subject/participant Indicator of whether hemodynamic augmentation is being given to the subject/participant Hemodynamic augmentation Yes, specify;No Yes, specify;No Alphanumeric

Hemodynamic augmentation – general: An intervention in systemic circulatory status that is aimed at establishing supraphysiological goals in terms of cardiac output or volume status or blood pressure or any combination

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:41:34.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54944 Ventilation mechanical any indicator VentlatnMechanclAnyInd Indicator of whether any mechanical ventilation was administered to the subject/particpant Indicator of whether any mechanical ventilation was administered to the subject/particpant Mechanical ventilation (invasive or noninvasive) No;Yes No;Yes Alphanumeric

Mechanical ventilation: Invasive or noninvasive ventilation at any time excluding strictly procedural/elective mechanical ventilation

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:25:00.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54934 Hemodynamic augmentation specify text HemodynamicAugmntatnSpecifyTxt The free-text field related to 'Hemodynamic augmentation indicator' for specifying the hemodynamic augmentation being given The free-text field related to 'Hemodynamic augmentation indicator' for specifying the hemodynamic augmentation being given Hemodynamic augmentation: Yes, specify Alphanumeric

Hemodynamic augmentation – general: An intervention in systemic circulatory status that is aimed at establishing supraphysiological goals in terms of cardiac output or volume status or blood pressure or any combination

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:44:36.0 ICU Therapies [php] [php_1] 500

Free-Form Entry

C54945 Ventilation mechanical invasive indicator VentlatnMechanclInvsvInd Indicator of whether any invasive mechanical ventilation was administered to the subject/particpant Indicator of whether any invasive mechanical ventilation was administered to the subject/particpant Invasive mechanical ventilation No;Yes No;Yes Alphanumeric

Invasive mechanical ventilation: Yes if intubation and invasive ventilation at any point (regardless if the patient also received non-invasive ventilation before or after) excluding strictly procedural/elective mechanical ventilation

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:25:00.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54935 Hypervolemic therapy volume augmentation indicator HyprvlmcThrpyVolmAugmntatnInd Indicator of whether hypervolemic therapy or volume augmentation is being given to the subject/participant Indicator of whether hypervolemic therapy or volume augmentation is being given to the subject/participant Hypervolemic therapy/volume augmentation Yes, specify;No Yes, specify;No Alphanumeric

Hypervolemic therapy/volume augmentation – general: An intervention aimed at establishing supraphysiological goals in terms of volume status indicated by means of fluid balance and/or- intake, or cardiac output or central venous pressure/pulmonary artery occlusion pressure (CVP/PAOP) or any combination, thus excluding euvolemia

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:41:34.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54946 Ventilation mechanical noninvasive indicator VentlatnMechanclNoninvsvInd Indicator of whether noninvasive mechanical ventilation was administered to the subject/particpant Indicator of whether noninvasive mechanical ventilation was administered to the subject/particpant Noninvasive mechanical ventilation No;Yes No;Yes Alphanumeric

Noninvasive mechanical ventilation: Yes if patient only received non-invasive ventilation (never intubated excluding strictly procedural/elective intubation) during the hospitalization. This variable should be defined as positive pressure NIV and NOT include patients who receive constructive positive airway pressure (CPAP) at night for obstructive sleep apnea (OSA).

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:25:00.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54936 Hypervolemic therapy volume augmentation specify text HypvlmcThpyVolmAugmntnSpcfTxt The free-text field related to 'Hypervolemic therapy volume augmentation' for specifying the hypervolemic therapy or volume augmentation being given The free-text field related to 'Hypervolemic therapy volume augmentation' for specifying the hypervolemic therapy or volume augmentation being given Hypervolemic therapy/volume augmentation: Yes, specify Alphanumeric

Hypervolemic therapy/volume augmentation – general: An intervention aimed at establishing supraphysiological goals in terms of volume status indicated by means of fluid balance and/or- intake, or cardiac output or central venous pressure/pulmonary artery occlusion pressure (CVP/PAOP) or any combination, thus excluding euvolemia

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:44:36.0 ICU Therapies [php] [php_1] 500

Free-Form Entry

C54947 Ventilation mechanical any total duration VentlatnMechnclAnyTotlDur Total duration in days of all mechanical ventilation administered to the subject/particpant Total duration in days of all mechanical ventilation administered to the subject/particpant Total length of mechanical ventilation (days, both invasive and noninvasive) Numeric Values

Excluding strictly procedural/elective mechanical ventilation and NOT including patients who receive constructive positive airway pressure (CPAP) at night for obstructive sleep apnea (OSA).

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:29:45.0 ICU Therapies [php] [php_1]

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Days
C54937 Hypervolemic therapy volume augmentation range HyprvlmcThrpyVolmAugmntatnRng Range of hypervolemic therapy/volume augmentation Range of hypervolemic therapy/volume augmentation Hypervolemic therapy/volume augmentation - specific goal Alphanumeric

Hypervolemic therapy/volume augmentation – specific value: Upper and lower limit of hypervolemic therapy/volume augmentation goal. Fluid balance and/or- intake , or cardiac output or CVP/PAOP or any combination.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:00:55.0 ICU Therapies [php] [php_1] 255

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C54948 Ventilation mechanical invasive total duration VentlatnMechnclInvsvTotlDur Total duration in days of invasive mechanical ventilation administered to the subject/particpant Total duration in days of invasive mechanical ventilation administered to the subject/particpant Total duration of invasive mechanical ventilation (days) Numeric Values

Excluding strictly procedural/elective mechanical ventilation

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:29:45.0 ICU Therapies [php] [php_1]

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Days
C54927 Blood pressure systolic target mean measurement BldPrssrSystlcTrgtMnMeasr Target measurement for mean systolic blood pressure Target measurement for mean systolic blood pressure Routine blood pressure management: upper target mean value (mmHg) Numeric Values

Routine upper/lower targets for mean arterial pressure

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:29:39.0 ICU Therapies [php] [php_1]

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Millimeters of mercury
C54938 Fever management threshold temperature value FevrMgmtThreshldTempVal Value in degrees centigrade of the threshold temperature prompting therapy for fever management Value in degrees centigrade of the threshold temperature prompting therapy for fever management Target for fever management target (°C) Numeric Values

Fever management target: Elevated body temp that prompts therapy in °C

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211-240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263-277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683-690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129-1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:04:38.0 ICU Therapies [php] [php_1]

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37 Degrees centigrade
C54949 Ventilation mechanical noninvasive total duration VentlatnMechnclNonInvsvTotlDur Total duration in days of noninvasive mechanical ventilation administered to the subject/particpant Total duration in days of noninvasive mechanical ventilation administered to the subject/particpant Total duration of noninvasive mechanical ventilation (days) Numeric Values

Excluding strictly procedural/elective mechanical ventilation and NOT including patients who receive constructive positive airway pressure (CPAP) at night for obstructive sleep apnea (OSA).

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:29:45.0 ICU Therapies [php] [php_1]

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Days
C54928 Blood pressure diastolic target mean measurement BldPrssrDstlcTrgtMnMeasr Target measurement for mean diastolic blood pressure Target measurement for mean diastolic blood pressure Routine blood pressure management: lower target mean value (mmHg) Numeric Values

Routine upper/lower targets for mean arterial pressure

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:29:39.0 ICU Therapies [php] [php_1]

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Millimeters of mercury
C54939 Sodium level upper threshold value SodiumLvlUpThreshldVal Value of upper sodium threshold level prompting treatment Value of upper sodium threshold level prompting treatment Sodium management: Upper Limit Numeric Values

Sodium management - upper/lower limit: Upper/lower value of sodium levels that prompt treatment (Units will depend on country of origin). Use 'Sodium unit of measure' to capture units.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1]

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C54950 Intracranial hypertension cerebral edema osmotherapy indicator IntCrnHyptnsnCrbrlEdmaOsmthInd Indicator of whether osmotherapy was administered for intracranial hypertension or cerebral edema Indicator of whether osmotherapy was administered for intracranial hypertension or cerebral edema Osmotherapy for intracranial hypertension or cerebral edema Yes, specify;No Yes, specify;No Alphanumeric

Any use of osmotherapy (mannitol, hypertonic saline or others) for treatment of intracranial hypertension or brain edema

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1]

Single Pre-Defined Value Selected

C54929 Mean arterial pressure augmentation measurement MAPAugmentationMeasr Measurement of mean arterial pressure (MAP) augmentation Measurement of mean arterial pressure (MAP) augmentation Blood pressure augmentation (mmHg): Mean arterial pressure (MAP) Numeric Values

Blood pressure augmentation goal: Blood pressure augmentation goal (MAP or systole) beyond routine upper limit of blood pressure for prevention or treatment of delayed cerebral ischemia

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 12:35:33.0 ICU Therapies [php] [php_1]

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Millimeters of mercury
C54940 Blood glucose lower threshold value BldGlucoseLoThreshldVal Value of blood glucose lower threshold prompting treatment Value of blood glucose lower threshold prompting treatment Glucose control: Lower limit Numeric Values

Glucose control – upper/lower limit: Upper/lower value of blood sugar levels that prompt treatment (Units will depend on country of origin). Use 'Blood glucose unit of measure' to capture units.

Diringer MN, Bleck TP, Claude Hemphill J 3rd, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES Jr, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G; Neurocritical Care Society. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011;15(2):211–240. • Suarez JI, Martin RH. Treatment of subarachnoid hemorrhage with human albumin: ALISAH study. Rationale and design. Neurocrit Care. 2010;13(2):263–277. • Suarez JI, Martin RH, Calvillo E, Dillon C, Bershad EM, Macdonald RL, Wong J, Harbaugh R; ALISAH Investigators. The Albumin in Subarachnoid Hemorrhage (ALISAH) multicenter pilot clinical trial: safety and neurologic outcomes. Stroke. 2012;43(3):683–690. • van der Jagt M. Fluid management of the neurological patient: a concise review. Crit Care. 2016;20(1):126. • van der Jagt M, Haitsma I. An injured brain needs cooling down: no. Intensive Care Med. 2015;41(6):1129–1131 Adult;Pediatric Supplemental 1.00 2017-04-13 13:09:39.0 ICU Therapies [php] [php_1]

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CSV