CDE Detailed Report

Disease: content
Subdomain Name: Laboratory Tests and Biospecimens/Biomarkers
CRF: welcome

Displaying 151 - 166 of 166
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C12268 Immunohistochemical stain used muscle biopsy and autopsy type ImmhistchmclStnUseMuscBpAp Which immunohistochemical stains were used on muscle biopsy? Which immunohistochemical stains were used on muscle biopsy? Which immunohistochemical stains were used? Myosin immunohistochemistry;Dystrophin panel;Other stains for limb-girdle or congenital muscular dystrophy;Inflammatory myopathy panel;Protein aggregate myopathy panel Myosin immunohistochemistry;Dystrophin panel;Other stains for limb-girdle or congenital muscular dystrophy;Inflammatory myopathy panel;Protein aggregate myopathy panel Alphanumeric

Choose all that apply. If dystrophin panel, Other stains for limb-girdle or congenital muscular dystrophy, or Inflammatory myopathy panel were answered for "Which immunohistochemical stains were performed?", specify stains used.

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Multiple Pre-Defined Values Selected
C12527 Biopsy and autopsy type 2 predominance fiber percentage value BpApTyp2PredomFibPctVal Percentage of Type 2 predominance fiber present Percentage of Type 2 predominance fiber present Percent of Type 2 fibers Alphanumeric

Only answered if "Type 2 predominance' fiber is selected

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 255

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C19973 Immunohistochemistry neuronal nitric oxide synthase status IHCnNOSStat The status of neuronal nitric oxide synthase in immunohistochemistry The status of neuronal nitric oxide synthase in immunohistochemistry nNOS Absent;Reduced;Normal Absent;Reduced;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19909 Biopsy and autopsy nuclear bags clumps status BpApAutoNucBagsClumpStat The status as related to presence of nucelar bags/clumps The status as related to presence of nucelar bags/clumps Nuclear bags/clumps Absent;Present Absent;Present Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C12234 Preservation technique used amount value PresrvtnTechnqUseAmntVal Value of the amount of preservation solution or material used to preserve the specimen Value of the amount of preservation solution or material used to preserve the specimen Amount Alphanumeric

Answer for the freezing or fixation technique used. Answer should be recorded in milligrams (mg). If amount used is not known, select Not known.

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 255

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 milligram
C19941 Biopsy and autopsy distribution type BpApDistrTyp Type of distribution of inflammation Type of distribution of inflammation Distribution Perivascular;Focal;Diffuse;Endomysial;Involving fascia;Perimysial Perivascular;Focal;Diffuse;Endomysial;Involving fascia;Perimysial Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19952 Immunohistochemistry dystrophin rod domain status IHCDysRodDomStat The status of dystrophin rod domain (DYS1) in immunohistochemistry The status of dystrophin rod domain (DYS1) in immunohistochemistry Dystrophin rod domain (DYS1) Absent;Reduced;Cytoplasmic;Normal Absent;Reduced;Cytoplasmic;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19888 Age biopsy year value AgeBiopsyYearVal Age (in years) of participant/subject at biopsy Age (in years) of participant/subject at biopsy Age at biopsy Numeric Values Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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 year
C19984 Immunohistochemistry CD138 percentage value IHCCD138PercentVal Percent value of C138 Percent value of C138 Present in Numeric Values Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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 0 100 percent
C19920 Biopsy and autopsy central cores status BpApCentralCoreStat Central cores status in biopsy Central cores status in biopsy Central cores Absent;Sparse;Moderate Absent;Sparse;Moderate Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C12251 Biopsy and autopsy atrophy or hypotrophy type BpApAtrphyHypotrphyTyp Atrophy/ hypertrophy type Atrophy/ hypotrophy type Specify All fibers within the specimen;Subset of fibers, leading to excessive variation in fiber size;Atrophic/hypertrophic fiber shape;Nuclear bags/clumps;Perifascicular distribution All fibers within the specimen;Subset of fibers, leading to excessive variation in fiber size;Atrophic/hypertrophic fiber shape;Nuclear bags/clumps;Perifascicular distribution Alphanumeric

Only answered if "Atrophy/Hypotrophy" is answered for "Which of the following diagnostic abnormalities were noted on histochemical stains?"

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19963 Immunohistochemistry beta dystroglycan status IHCBetaDystroglyStat The status of Beta dystroglycan in immunohistochemistry The status of Beta dystroglycan in immunohistochemistry Beta dystroglycan Absent;Reduced;Normal Absent;Reduced;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19899 Elevated C reactive protein value ElevatCReactProtVal The elevated C-reactive protein value The elevated C-reactive protein value Patient Value Numeric Values

No instructions available

 No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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C19995 Immunohistochemistry ubiquitin aggregate level status IHCUbiquitinAggregLvlStat Level of ubiquitin aggregate Level of ubiquitin aggregate Myotilin Normal;Increased Normal;Increased Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19931 Biopsy and autopsy tubular aggregates estimated percentage value BpApTubAggEstCt Tubular aggregates estimated percentage value Tubular aggregates estimated percentage value Moderate (present in:) Numeric Values No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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 0 100 percent
C12269 Biopsy and autopsy immunohistochemical immunofluorescence assays performed BpApImnhschmImnflrsncAssyPerf List of stains used List of stains used Immunohistochemical/ Immunofluorescence assays performed Alphanumeric

List the stains used based upon answers in question 3

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 255

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CSV