CDE Detailed Report
Disease: Multiple Sclerosis
Subdomain Name: Imaging Diagnostics
CRF: Imaging Analysis Technique and Results - Baseline
Displaying 51 - 81 of 81
Subdomain Name: Imaging Diagnostics
CRF: Imaging Analysis Technique and Results - Baseline
Displaying 51 - 81 of 81
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C15462 | Imaging spinal cord volume value | ImgSpinCordVolVal | Volume of the spinal cord | Volume/area of the spinal cord | Spinal cord measurement | Numeric Values |
Record in ml and use 2 decimal places. |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
milliliter | |||||||||
| C19006 | Imaging brain measured structure other text | ImgBrainStructureOTH | The free-text field related to 'Imaging brain measured structure type' specifying other text. The structure of the brain volume measurement | The free-text field related to 'Imaging brain measured structure type' specifying other text. The structure of the brain volume measurement | Other, specify | Alphanumeric |
Exploratory for Imaging studies Only answered if "Brain structure volume" was answered for "Technique" |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15405 | Imaging brain volume fraction value | ImgBrainVolFraVal | Ratio of whole brain parenchymal volume to total intracranial volume or other head-size normalization volume | Ratio of whole brain parenchymal volume to total intracranial volume or other head-size normalization volume | Brain volume fraction | Numeric Values |
Highly recommended for: Imaging studies. Answer questions and sub-questions for brain volume, or brain volume fraction but not both. Record brain volume fraction. Use 4 decimal places. Acceptable range is 0.5000 - 1.0000. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0.5 | 1 | ||||||||
| C15504 | Imaging spinal cord volume/cross-sectional area technique type | ImgSpnlCrdVolCrsSecAreaTechTyp | Method used to determine the cord cross-sectional area or volume as a measure of cord atrophy | Method used to determine the cord cross-sectional area or volume as a measure of cord atrophy | Technique Used | Manual tracing by experienced reader;Semi-automated (calculated through software, verified by experienced reader);Losseff(LOSspin echoFF)-3mmx5 axial slices from C2-3 up;Fully automated segmentation;Other, specify | Manual tracing by experienced reader;Semi-automated (calculated through software, verified by experienced reader);Losseff(LOSspin echoFF)-3mmx5 axial slices from C2-3 up;Fully automated segmentation;Other, specify | Alphanumeric |
Exploratory for Imaging studies No additional instructions |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15433 | Imaging brain volume fraction technique type | ImgBrainVolFractTechTyp | Image analysis method used to calculate whole brain volume fraction | Image analysis method used to calculate whole brain volume fraction | Technique Used | Brain parenchymal fraction (BV/TIV);Brain parenchymal fraction (BV/BOCV);Other, specify | Brain parenchymal fraction (BV/TIV);Brain parenchymal fraction (BV/BOCV);Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18589 | Imaging spinal cord area value | ImgSpinCordAreaVal | Area of the spinal cord | Area of the spinal cord | Spinal cord measurement | Numeric Values |
Record in mm2 and use 2 decimal places. |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-07-30 14:29:49.047 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
square millimeter | |||||||||
| C02499 | Imaging pulse sequence type | ImgPulseSeqTyp | Type of imaging pulse sequence used | Type of imaging pulse sequence used | Image pulse sequence used;Sequence Type | T1;T2;FLAIR;DWI;GRE;SWI;DTI;MRSI;PWI;Gradient-echo;Pulsed-ASL;Continuous-ASL;Pseudocontinuous-ASL;Post-contrast FLAIR;Post-contrast T1-weighted;COW MRA;TOF Neck MRA;CE MRA;Other, specify;FLASH;MPRAGE;SPGR;SPACE/VISTA;TSE/FSE;Dual echo PD/T2W SE;PD SE;T2W SE;T1W SE;T1W 3D gradient-echo;T1-weighted spin echo with contrast;T1-weighted spin echo without contrast;PD/T2W FSE;DIR;PSIR;fMRI;PRESS;Spectroscopic imaging 2D;Spectroscopic imaging 3D;Spin echo;STEAM;Single voxel spectroscopy (SVS);Pulsed-ASL;Continuous-ASL;Pseudocontinuous-ASL;Multivoxel spectroscopy;Unlocalized spectroscopy;ISIS;DWI/ADC;rFOV;EPI | T1;T2;FLAIR;DWI;GRE;SWI;DTI;MRSI;PWI;Gradient-echo;Pulsed-ASL;Continuous-ASL;Pseudocontinuous-ASL;Post-contrast FLAIR;Post-contrast T1-weighted;COW MRA;TOF Neck MRA;CE MRA;Other, specify;FLASH;MPRAGE;SPGR;SPACE/VISTA;TSE/FSE;Dual echo PD/T2W SE;PD SE;T2W SE;T1W SE;T1W 3D gradient-echo;T1-weighted spin echo with contrast;T1-weighted spin echo without contrast;PD/T2W FSE;DIR;PSIR;fMRI;PRESS;Spectroscopic imaging 2D;Spectroscopic imaging 3D;Spin echo;STEAM;Single voxel spectroscopy (SVS);Pulsed-ASL;Continuous-ASL;Pseudocontinuous-ASL;Multivoxel spectroscopy;Unlocalized spectroscopy;ISIS;DWI/ADC;Reduced field of view (rFOV);Echo Planar Imaging (EPI) | Alphanumeric |
Exploratory for Imaging studies In this row, for each column list each pulse sequence checked in question #3 (e.g., MPRAGE, FLAIR, DTI etc.) |
No references available | Adult;Pediatric | Exploratory | 4.00 | 2024-02-29 15:47:35.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C15367 | Imaging cortical lesion count | ImgCrtclLesnCt | Total number of lesions located in the brain cortex or lesions in the subcortical WM also involving the cortex | Total number of lesions located in the brain cortex or lesions in the subcortical WM also involving the cortex | Number of cortical lesions | Numeric Values |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
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| C15466 | Imaging tissue integrity region type | ImgTissueIntegRegTyp | The areas of the brain where tissue integrity is measured | The areas of the brain where tissue integrity is measured | N/A | Whole brain;Normal-appearing GM;Normal-appearing WM | Whole brain;Normal-appearing GM;Normal-appearing WM | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C19007 | Imaging spinal cord lesion technique other text | ImgSpinCordLesnTechOTH | The free-text field related to 'Imaging spinal cord lesion technique type' specifying other text. Method used to determine the number of lesions located in the spinal cord | The free-text field related to 'Imaging spinal cord lesion technique type' specifying other text. Method used to determine the number of lesions located in the spinal cord | Other, specify | Alphanumeric |
Exploratory for Imaging studies No additional instructions |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15407 | Imaging ventricular volume measurement | ImgVentrclVolMeas | Volume measurement of the ventricles | Volume measurement of the ventricles | Ventricular volume | Numeric Values |
Answer questions and sub-questions for ventricular volume, or ventricular volume fraction but not both. Record ventricular volume in mL. Use 2 decimal places. Acceptable range is 0.00 - 1000.00. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0 | 1000 | milliliter | |||||||
| C15506 | Imaging spinal cord volume/cross-sectional area slice thickness measurement | ImgSpinCordVolArSliThiMeasr | Thickness of the spinal cord volume/cross-sectional area optical slice | Thickness of the spinal cord volume/cross-sectional area optical slice | Slice thickness | Numeric Values |
Exploratory for Imaging studies Record value in millimeters (mm) |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
millimeter | |||||||||
| C15434 | Imaging white matter volume fraction value | ImgWMVolFractVal | Ratio of white matter volume to total intracranial volume or other head-size normalization volume | Ratio of white matter volume to total intracranial volume or other head-size normalization volume | White matter volume fraction | Numeric Values |
Exploratory for Imaging studies Answer questions and sub-questions for white matter volume, or white matter volume fraction but not both. Use 4 decimal places when recording volume fraction. Acceptable range is 0.2000 - 0.8000. |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0.2 | 0.8 | ||||||||
| C18694 | Imaging diffusion measurement other text | ImgDiffusionMeasrOTH | The free-text field related to 'Imaging diffusion measurement type' specifying other text. Type of diffusion tensor imaging (DTI) measurement | The free-text field related to 'Imaging diffusion measurement type' specifying other text. Type of diffusion tensor imaging (DTI) measurement | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C08244 | Imaging slice thickness value | ImgSliceThicknessVal | Value of the thickness of the slice measured in millimeters (mm) | Value of the thickness of the slice measured in millimeters (mm) | Slice thickness | Numeric Values |
Record value in millimeters (mm). If the sequences are different for T1 and T2 sequence parameters, record the T2 parameters as indicated. If they are the same, leave the T2 parameters section blank. If the sequences are different for T1 and FLAIR sequence parameters, record the FLAIR parameters as indicated. If they are the same, leave the FLAIR parameters section blank. DTI sequence parameters |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0 | 99 | millimeter | |||||||
| C15372 | Imaging thalamus lesion count | ImgThalLesnCt | Total number of lesion(s) located in the thalamus | Total number of lesions located in the thalamus | Number of thalamus lesions | Numeric Values |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0 | 1000 | ||||||||
| C15469 | Imaging magnetization transfer ratio (MTR) measurement type | ImgMTRMeasrTyp | Magnetization transfer ratio measure | Magnetization transfer ratio measure | N/A | Mean MTR;MTR histogram peak position;MTR histogram peak height;Other, specify | Mean MTR;MTR histogram peak position;MTR histogram peak height;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C19008 | Imaging spinal cord volume/cross-sectional area technique other text | ImgSpinCrdVolCrsSecAreaTechOTH | The free-text field related to 'Imaging spinal cord volume/cross-sectional area technique type' specifying other text. Method used to determine the cord cross-sectional area or volume as a measure of cord atrophy | The free-text field related to 'Imaging spinal cord volume/cross-sectional area technique type' specifying other text. Method used to determine the cord cross-sectional area or volume as a measure of cord atrophy | Other, specify | Alphanumeric |
Exploratory for Imaging studies No additional instructions |
No references available | Adult;Pediatric | Exploratory | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15408 | Imaging T1 hypointense lesion technique type | ImgT1HypinLesnTechTyp | Method used to determine the total number of T1 hypointense lesions | Method used to determine the total number of T1 hypointense lesions | Technique Used | Visual determination by experienced reader;Semi-automated (calculated through software, verified by experienced reader);Fully automated segmentation and counting;Other, specify | Visual determination by experienced reader;Semi-automated (calculated through software, verified by experienced reader);Fully automated segmentation and counting;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15511 | Imaging tissue integrity type performed indicator | ImgTissueIntegTypPerfInd | Whether the imaging type was performed on specific brain tissue | Whether the imaging type was performed on specific brain tissue | Done | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric |
Answer for all tissue integrity types. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15442 | Imaging central cerebral volume measurement | ImgCenCereVolMeasr | Central cerebral volume measurement | Central cerebral volume measurement | Central cerebral volume | Numeric Values |
Record in mL and use 2 decimal places. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
milliliter | |||||||||
| C18708 | Imaging pulse sequence type other text | ImgPulseSeqTypOTH | The free-text field related to 'Imaging pulse sequence type', specifying other text. Type of imaging pulse sequence used | The free-text field related to 'Imaging pulse sequence type', specifying other text. Type of imaging pulse sequence used | Other, specify | Alphanumeric |
Exploratory for Imaging studies In this row, for each column list each pulse sequence checked in question #3 (e.g., MPRAGE, FLAIR, DTI etc.) |
No references available | Adult;Pediatric | Exploratory | 2.00 | 2022-07-01 14:55:04.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C10576 | Imaging in plane resolution axis 1 measurement | ImgInPlaneRsltnAxis1Measr | Measurement of axis 1 of in-plane spatial resolution used in imaging acquisition | Measurement of axis 1 of in-plane spatial resolution used in imaging acquisition | In slice resolution | Numeric Values |
Record value in millimeters (mm) |
No references available | Adult;Pediatric | Supplemental | 3.10 | 2024-02-29 15:47:41.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
square millimeter | |||||||||
| C15375 | Imaging Gadolinium-enhancing lesion count | ImgGdEnLesnCt | Total number of all focal lesions that are gadolinium (Gd)-enhancing on T1-weighted brain images | Total number of all focal lesions that are gadolinium-enhancing on T1-weighted brain images | Total number of Gd-enhancing lesions | Numeric Values |
Expected range 0 - 1000. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0 | 1000 | ||||||||
| C15470 | Imaging magnetization transfer ratio (MTR) result value | ImgMTRResltVal | The magnetization transfer ratio (MTR) result | The magnetization transfer ratio (MTR) result | N/A | Numeric Values |
Record a value for each MTR measure and each region of the brain. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
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| C19025 | Imaging tissue integrity measure technique other text | ImgTissueIntegMeasTechOTH | The free-text field related to 'Imaging tissue integrity measure technique type' specifying other text. Type of imaging sequence used | The free-text field related to 'Imaging tissue integrity measure technique type' specifying other text. Type of imaging sequence used | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15411 | Imaging ventricular volume fraction value | ImgVentrclVolFracVal | Ratio of ventricular volume to total intracranial volume or other head-size normalization volume | Ratio of ventricular volume to total intracranial volume or other head-size normalization volume | Ventricular volume fraction | Numeric Values |
Answer questions and sub-questions for ventricular volume, or ventricular volume fraction but not both. Record ventricular volume fraction. Use 4 decimal places. Acceptable range is 0.0000 - 0.5000. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
0 | 0.5 | ||||||||
| C15515 | Imaging tissue integrity whole brain measurement indicator | ImgTissIntegWholeBrainMeasInd | Whether measurements of the tissue integrity of the whole brain were taken | Whether measurements of the tissue integrity of the whole brain were take | Whole Brain | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric |
Answer for all tissue integrity types. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C10837 | Imaging gap between slices measurement | ImgGapBetwnSlicesMeasr | Measurement of the gap between slices used in imaging acquisition | Measurement of the gap between slices used in imaging acquisition | Gap | Numeric Values |
Record value in millimeters (mm) |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
millimeter | |||||||||
| C15445 | Imaging cortical thickness measurement | ImgCortThiMeasr | Thickness of cerebral cortex measurement | Thickness of cerebral cortex measurement | Cortical thickness | Numeric Values |
Record in mm and use 2 decimal places. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations |
Free-Form Entry |
millimeter | |||||||||
| C18999 | Imaging T2W image technique other text | ImgT2WImgTechOTH | The free-text field related to 'Imaging T2W image technique type' specifying other text. Method used to determine the total volume of white matter hyperintensities on T2-weighted image | The free-text field related to 'Imaging T2W image technique type' specifying other text. Method used to determine the total volume of white matter hyperintensities on T2-weighted image | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Imaging Analysis Technique and Results - Baseline | Imaging Diagnostics | Assessments and Examinations | 4000 |
Free-Form Entry |
