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Quantitative%20Sudomotor%20Axon%20Reflex%20Test%20(QSART)
Quantitative%20Sudomotor%20Axon%20Reflex%20Test%20(QSART)
| Availability |
*This test requires advanced equipment and specific training for scoring. For Training please email Dr. Phillip A. Low
The Patent for this test is held by: WR Medical Electronics Co.
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| Classification |
Supplemental: Neuromuscular Diseases (NMD)
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| Short Description of Instrument |
The Quantitative Sudomotor Axon Reflex Test (QSART) depends on the integrity of postganglionic sympathetic sudomotor axons and sweat glands. The stimulus for the QSART is iontrophoretically applied acetylcholine.
Recordings are typically performed from multiple sites, such as the medial forearm, proximal leg, distal leg and dorsum of the foot.
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| Scoring and Psychometric Properties |
Scoring: The latency, duration, amplitude of the response are recorded.
Psychometric Properties: The QSART has been found to be sensitive and reproducible.
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| References |
Low PA. Laboratory evaluation of autonomic dysfunction, In: Low PA, ed. Clinical autonomic disorders: evaluation and management. 2nd ed. Philadelphia: Lippincott-Raven, 1997: 179-208.
Low PA,. Composite autonomic scores scale for laboratory quantification of generalized autonomic failure. Mayo Clin Proc 1993; 68: 748-752.
Cohen J, Low P, Fealey R, et al. Somatic and autonomic function in progressive autonomic failure and multiple systems atrophy. Ann Neurol 1987; 22: 692-699.
Low PA, Caskey PE, Tuck RR, Fealey RD, Dyck PJ. Quantitative sudomotor axon reflex test in normal and neuropathic subjects. Ann Neurol. 1983;14(5):573-580.
Document last updated August 2022
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