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Alzheimer's Disease Assessment Scale-Cognition (ADAS-cog)
Availability
Please visit this website for more information about the instrument: Alzheimer's Disease Assessment Scale-Cognition
Classification
Supplemental: Parkinson's Disease (PD)
Short Description of Instrument
The Alzheimer's Disease Assessment Scale- Cognition (ADAS-cog) was developed specifically to address selected aspects of cognitive function in Alzheimer's Disease (AD). The 11-item scale is designed to address language and memory skills in AD patients.
 
Construct measured: Cognition (specific for: memory, language, praxis).
 
Generic vs. disease specific: Designed specific to Alzheimer's disease.
 
Means of administration: Rater administered paper and pencil. Training required.
 
Intended respondent (e.g., patient, caregiver, etc.): Patient.
Scoring
Scoring: maximum: 70; higher = worse cognition.
References
Balsis, S., Unger, A. A., Benge, J. F., Geraci, L., & Doody, R. S. (2012). Gaining precision on the Alzheimer's Disease Assessment Scale-cognitive: a comparison of item response theory-based scores and total scores. Alzheimers Dement, 8(4), 288-294.
Baron, M., Jimenez Escrig, A., Orensanz, L., & Gobernado, J. M. (1998). The Alzheimer's disease assessment scale. Neurology, 50(5), 1516.
Chu, L. W., Chiu, K. C., Hui, S. L., Yu, G. K., Tsui, W. J., & Lee, P. W. (2000). The reliability and validity of the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) among the elderly Chinese in Hong Kong. Ann Acad Med Singapore, 29(4), 474-485.
Doraiswamy, P. M., Bieber, F., Kaiser, L., Krishnan, K. R., Reuning-Scherer, J., & Gulanski,
B. (1997). The Alzheimer's Disease Assessment Scale: patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials. Neurology, 48(6), 1511-1517.
Doraiswamy, P. M., Kaiser, L., Bieber, F., & Garman, R. L. (2001). The Alzheimer's Disease Assessment Scale: evaluation of psychometric properties and patterns of cognitive decline in multicenter clinical trials of mild to moderate Alzheimer's disease. Alzheimer Dis Assoc Disord, 15(4), 174-183.
Gillen, T. E., Gregg, K. M., Yuan, H., Kurth, M. C., & Krishnan, K. R. (2001). Clinical trials in Alzheimer's disease. Calculating Alzheimer's Disease Assessment Scale-cognitive subsection with the data from the consortium to establish a registry for Alzheimer's disease. Psychopharmacol Bull, 35(2), 83-96.
Graham, D. P., Cully, J. A., Snow, A. L., Massman, P., & Doody, R. (2004). The Alzheimer's Disease Assessment Scale-Cognitive subscale: normative data for older adult controls.
Alzheimer Dis Assoc Disord, 18(4), 236-240.
Instruments: Alzheimer's Disease Assessment Scale-Cognitive (2008). Retrieved 2/27, 2015, from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929311/
Khan, A., Yavorsky, C., DiClemente, G., Opler, M., Liechti, S., Rothman, B., & Jovic, S. (2013). Reliability of the Alzheimer's disease assessment scale (ADAS-Cog) in longitudinal studies. Curr Alzheimer Res, 10(9), 952-963.
Liu, H. C., Teng, E. L., Chuang, Y. Y., Lin, K. N., Fuh, J. L., & Wang, P. N. (2002). The
Alzheimer's Disease Assessment Scale: findings from a low-education population.
Dement Geriatr Cogn Disord, 13(1), 21-26.
Mohs, R. C., Knopman, D., Petersen, R. C., Ferris, S. H., Ernesto, C., Grundman, M., . . . Thal, L. J. (1997). Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord, 11 Suppl 2, S13-S21.
Pena-Casanova, J. (1997). Alzheimer's Disease Assessment Scale--cognitive in clinical practice. Int Psychogeriatr, 9 Suppl 1, 105-114.
Rosen, W. G., Mohs, R. C., & Davis, K. L. (1984). A new rating scale for Alzheimer's disease. Am J Psychiatry, 141(11), 1356-1364.
Rozzini, L., Vicini Chilovi, B., Bertoletti, E., Conti, M., Delrio, I., Trabucchi, M., & Padovani, A. (2008). The importance of Alzheimer disease assessment scale-cognitive part in predicting progress for amnestic mild cognitive impairment to Alzheimer disease. J Geriatr Psychiatry Neurol, 21(4), 261-267.

 

Document last updated July 2019