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NINDS CDE Notice of Copyright
Stroke Impact Scale (SIS)
The SIS is copyrighted by the University of Kansas: Stroke Impact Scale website.
Non- English language translations are available from PROQOLID: Non-English language translations of SIS.
Supplemental: Stroke
Exploratory: Unruptured Cerebral Aneurysms and Subarachnoid Hemorrhage (SAH)
Short Description of Instrument
Purpose: The Stroke Impact Scale is a stroke-specific, self-report, health status measure. It was designed to assess multidimensional stroke outcomes, including strength, hand function, activities of daily living/ instrumental activities of daily living (ADL/IADL), mobility, communication, emotion, memory and thinking, and participation. The SIS can be used both in clinical and research settings.
Overview: It was designed to assess multidimensional stroke outcomes. The SIS version
3.0 includes 59 items and assesses 8 domains: Strength - 4 items, Hand function - 5 items, ADL/IADL - 10 items, Mobility - 9 items, Communication - 7 items, Emotion - 9 items, Memory and thinking - 7 items, Participation/Role function - 8 items.
Time: There is no set time limit for this examination. The SIS can be administered in person, over the phone or by mail.
Other Important Notes: Alternate forms of the Stroke Impact Scale include the SIS-16, developed to address the lack of sensitivity to differences in physical functioning in functional measures of stroke outcome. The SIS-16 consists of 16 items from the SIS 2.0: seven ADL/IADL items, eight Mobility items, and a single Hand Function item.
The SIS and the SIS-16 has been translated by MAPI Research Institute:
The SIS-16: The SIS-16 was recently developed as a short stand alone tool for measuring the physical aspects of stroke recovery. This version implements 16 questions from the SIS 3.0 across four of the eight domains to create a short composite.
Comments/Special Instructions
Scoring and Psychometric Properties
Scoring: The SIS is a patient-based, self-report scale in which each item is rated in a 5- point Likert scale in terms of the difficulty the patient has experienced in completing each item. A score of 1 = an inability to complete the item and a score of 5 = no difficulty experienced at all. Using an algorithm equivalent to the one used in the SF- 36, summative scores are generated for each domain.
The SIS is scored in the following way, for each domain:
Transformed Scale = [(Actual raw score - lowest possible raw score) / Possible raw score range] x 100.
Both the SIS version 3.0 and the SIS-16 are available in proxy version when patients are unable to complete them.
Psychometric Properties: The SIS is reliable, valid, and sensitive to change. Unlike the SF-36, it does not have a floor effect in stroke patients. There are clear differences when the SIS is done via proxy report versus self-report.
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Duncan PW, Lai SM, Tyler, DA, Perera, S, Reker, DM, Studenski, S. Evaluation of proxy responses to the Stroke Impact Scale. Stroke. 2002;33(11):2593-2599.
Duncan PW, Wallace D, Lai SM, Johnson D, Embretson S, Laster L J. The Stroke Impact Scale version 2.0: Evaluation of reliability, validity, and sensitivity to change. Stroke. 1999;30:2131-2140.
Duncan PW, Lai SM, Bode RK, Perea S, DeRosa JT, GAIN Americas Investigators. Stroke Impact Scale-16: A brief assessment of physical function. Neurology. 2003;60:291-296.
Lin K, Fu T, Wu C, Wang Y, Liu J, Hsieh C, Lin S. Minimal Detectable Change and Clinically Important Difference of the Stroke Impact Scale in Stroke Patients. Neurorehabilit. Neural Repair. 2010;24(5):486-492.


Document last updated April 2020