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NINDS CDE Notice of Copyright
Stroke Impact Scale (SIS)
The SIS is copyrighted by the University of Kansas: Stroke Impact Scale website.
Non- English language translations are available from PROQOLID: Non-English language translations of SIS.
Supplemental: Stroke
Exploratory: Unruptured Cerebral Aneurysms and Subarachnoid Hemorrhage (SAH)
Short Description of Instrument
Purpose: The Stroke Impact Scale is a stroke-specific, self-report, health status measure. It was designed to assess multidimensional stroke outcomes, including strength, hand function, activities of daily living/ instrumental activities of daily living (ADL/IADL), mobility, communication, emotion, memory and thinking, and participation. The SIS can be used both in clinical and research settings.
Overview: It was designed to assess multidimensional stroke outcomes. The SIS version
3.0 includes 59 items and assesses 8 domains: Strength - 4 items, Hand function - 5 items, ADL/IADL - 10 items, Mobility - 9 items, Communication - 7 items, Emotion - 9 items, Memory and thinking - 7 items, Participation/Role function - 8 items.
Time: There is no set time limit for this examination. The SIS can be administered in person, over the phone or by mail.
Scoring: The SIS is a patient-based, self-report scale in which each item is rated in a 5- point Likert scale in terms of the difficulty the patient has experienced in completing each item. A score of 1 = an inability to complete the item and a score of 5 = no difficulty experienced at all. Using an algorithm equivalent to the one used in the SF- 36, summative scores are generated for each domain.
The SIS is scored in the following way, for each domain:


    Transformed Scale = [(Actual raw score - lowest possible raw score) / Possible raw score range] x 100.

Both the SIS version 3.0 and the SIS-16 are available in proxy version when patients are unable to complete them.
Psychometric Properties: The SIS is reliable, valid, and sensitive to change. Unlike the SF-36, it does not have a floor effect in stroke patients. There are clear differences when the SIS is done via proxy report versus self-report.
Other Important Notes: Alternate forms of the Stroke Impact Scale include the SIS-16, developed to address the lack of sensitivity to differences in physical functioning in functional measures of stroke outcome. The SIS-16 consists of 16 items from the SIS 2.0: seven ADL/IADL items, eight Mobility items, and a single Hand Function item.
The SIS and the SIS-16 has been translated by MAPI Research Institute:
The SIS-16: The SIS-16 was recently developed as a short stand alone tool for measuring the physical aspects of stroke recovery. This version implements 16 questions from the SIS 3.0 across four of the eight domains to create a short composite.
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Duncan PW, Lai SM, Tyler, DA, Perera, S, Reker, DM, Studenski, S. Evaluation of proxy responses to the Stroke Impact Scale. Stroke. 2002;33(11):2593–2599.
Duncan PW, Wallace D, Lai SM, Johnson D, Embretson S, Laster L J. The Stroke Impact Scale version 2.0: Evaluation of reliability, validity, and sensitivity to change. Stroke. 1999;30:2131–2140.
Duncan PW, Lai SM, Bode RK, Perea S, DeRosa JT, GAIN Americas Investigators. Stroke Impact Scale-16: A brief assessment of physical function. Neurology. 2003;60:291–296.