Report Viewer

NINDS CDE Notice of Copyright
Multiple Sclerosis Quality of Life Inventory (MSQLI)
Availability
Please visit this website for more information about the instrument:  Multiple Sclerosis Quality of Life Inventory (MSQLI)
Classification
Supplemental: Multiple Sclerosis (MS)
Short Description of Instrument
Construct measured: Quality of life.
 
Generic vs. disease specific: Combines generic and disease specific items.
 
Means of administration: Self-Administered.
 
Intended respondent: Patient.
 
# of items: 10 scales.
 
# of subscales and names of sub-scales: Varies
 
# of items per sub-scale: Varies.
Comments/Special Instructions
Scoring: Each of the individual scales generates a separate score. In addition, some of the scales generate subscales, e.g., the SF-36, the Modified Fatigue Impact Scale (MFIS), the Perceived Deficits Questionnaire (PDQ), and the MOS Modified Social Support Survey (MSSS). There is no global composite combining all the scales into a single score.
 
Background: The Multiple Sclerosis Quality Life Inventory (MSQLI) is a battery consisting of 10 individual scales providing a quality of life measure that is both generic and MS-specific. (Fischer et al, 1999) The MSQLI consists of the following individual scales, 5 of which have both a standard and a short form. MSQLI components: Health Status Questionnaire (SF-36); MFIS; MOS Pain Effects Scale (PES); Sexual Satisfaction Scale (SSS); Bladder Control Scale (BLCS); Bowel Control Scale (BWCS); Impact of Visual Impairment Scale (IVIS); PDQ; Mental Health Inventory (MHI); MSSS.
Rationale/Justification
Strengths/ Weaknesses: The MSQLI addresses the concerns most relevant to the MS population. Although the standard version of the MSQLI is somewhat lengthy, short forms of many of the individual scales have been developed and these have psychometric properties comparable to the longer versions.
 
Psychometric Properties: There is good internal consistency reliability for the subscales of the MSQLI, with the lowest alpha being 0.67 (for social functioning on SF- 36). Other coefficients range from 0.78 (BWCS) to 0.97 (MSSS). Test-retest reliability on the SF-36 ranges from 0.60 (social functioning) to 0.81 (physical functioning). Good content validity for the MSQLI was ensured by the mode of development, which was designed to develop health-related QOL measures specifically for MS patients. The MSQLI requires further longitudinal testing to determine sensitivity to detect change in MS patients.
 
Availability: All scales must be acquired individually.
References
Archibald, C.J., McGrath, P., Ritvo, P.G., Fisk, J.D., & Murray, T.J. (1994). Pain in multiple sclerosis: prevalence, severity and impact on mental health. Pain, 58, 89-93.
 
Carter, S., Sciarra, D., & Merritt, H. (1950). The course of multiple sclerosis as determined by autopsy proven cases. Research Publications of the Association for Research in Nervous and Mental Diseases, 28, 471-511.
 
Cella, D.F., Dineen, K., Arnason, M., Reder, A., Webster, K.A., Karabatsos, G., Chang, C.,Lloyd, S., Mo, F., Steward, J., & Stefoski, D. (1996). Validation of the functional assessment of multiple sclerosis quality of life instrument. Neurology, 47, 129-139.
 
Cella, D.G., Tulsky, D.S., Gray, G., et al. (1993). The Functional Assessment of Cancer Therapy(FACT) Scale: development and validation of the general measure. Journal of Clinical Oncology, 11, 570-579.
 
Clifford, D.B. & Trotter, J.L. (1984). Pain in multiple sclerosis. Archives of Neurology, 41(12),1270-1272.
 
Fisk, J.D., Ritvo, P.G., Ross, L., Haase, D.A., Marrie, T.J., Schlech, W.F. (1994). Measuring the Functional Impact of Fatigue: Initial Validation of the Fatigue Impact Scale. Clinical Infectious Diseases, 18 (Suppl 1), S79-83.
 
Fisk, J.D., Pontefract, A., Ritvo, P.G., Archibald, C.J., & Murray, T.J. (1994). The Impact of Fatigue on Patients with Multiple Sclerosis. Canadian Journal of Neurological Sciences,21, 9-14.
 
Heitzmann, C.A., & Kaplan, R.M. (1988). Assessments of methods for measuring social support. Health Psychology, 7 (1), 75-109.
 
Kalb, R.C., LaRocca, N.G., & Kaplan, S.R. (1987). Sexuality. In L.C. Scheinberg, & N.J.Holland (Eds.), Multiple sclerosis: A guide for patients and their families (2nd ed.). New York: Raven Press.
 
Kaplan, R.M. & Toshima, M.T. (1990). The functional effects of social relationships on chronic illness and disability. In B.R. Sarason, I.G. Sarason & G.R. Pierce (Eds.), Social support: An interactional view. New York: John Wiley & Sons.
 
Kraft, G.H., Freal, J.E., Coryell, J.K. (1986). Disability, disease duration and rehabilitation services needs in multiple sclerosis: patient perspectives. Archives of Physical Medicine and Rehabilitation, 67, 164-168.
 
Krupp, L.B., Alverez, L.A., LaRocca, N.G., & Scheinberg, L.C. (1988). Fatigue in multiple sclerosis. Archives of Neurology, 45, 435-437.
 
LaRocca, N.G, Ritvo, P.G., Miller, D.M., Fischer, J.S., Andrews, H., & Paty, D.W. (1996 )Quality of life assessment in multiple sclerosis clinical trials: current status and strategies for improving multiple sclerosis clinical trial design. In D. Goodkin and R. Rudick (Eds.),Treatment of multiple sclerosis. London: Springer.
 
Moulin, D.E., Foley, K.M., & Ebers, G.C. (1988). Pain syndromes in multiple sclerosis. Neurology, 38, 1830-1834.
 
Nowinski, J.K., & LoPiccolo, J. (1979). Assessing sexual behavior in couples. Journal of Sex and Marital Therapy, 5, 224-243.
 
Rao, S.M., Leo, G.J., Bernadin, L., & Unverzagt, F. (1991). Cognitive dysfunction in multiple sclerosis. I. frequency, patterns, and prediction. Neurology, 41, 685-691.
Ritvo, P.G., Fisk, J.D., Archibald, C.J., Murray, T.J., & Field, C. (1996) Psychosocial and neurological predictors of mental health in multiple sclerosis. Journal of Clinical Epidemiology, 49, 467-472.
 
Scheinberg, L., & Holland, C. (1987). Multiple sclerosis: A guide for patients and their families(2nd ed.) . New York: Raven Press.
 
Schover, L.R., Friedman, J.M., Weiler, S.J., Heiman, J.R., & LoPiccolo, J. (1982). Multiaxial problem-oriented system for sexual dysfunctions. Archives of General Psychiatry, 39,614-619.
 
Sherbourne, C.D., & Stewart, A.L. (1991). The MOS Social Support Survey. Social Science and Medicine, 32, 705-714.
 
Sherbourne, C.D., Hays, R.D., Ordway, L., DiMatteo, M.R., & Kravitz, R.L. (1992). Antecedents of adherence to medical recommendations: results from the medical outcomes study. Journal of Behavioral Medicine, 15(5), 447-468.
 
Sherbourne, C. (1996). Personal Communication.
 
Sohlberg, M.M. & Mateer, C.A. (1987). Effectiveness of an attention training program. Journal of Clinical and Experimental Neuropsychology, 9, 117-130.
 
Stewart, A.L., Hays, R., Ware, J. (1988). Communication: The MOS Short-form General Health Survey - reliability and validity in a patient population. Medical Care, 26, 7.
 
Stewart, A.L., Greenfield, S., Hays, R.D., Wells, K., Rogers, W.H., Berry, S.D., McGlynn, E.A.& Ware, Jr., J. (1989). Functional status and well-being of patients with chronic conditions: Results from the Medical Outcomes Study. Journal of the American Medical Association, 262, 907-913.
 
Stewart, A.L., Hays, R.D., & Ware., J.E. (1988). The MOS Short-Form General Health Survey: reliability and validity in a patient population. Medical Care, 26, 724-735.
 
Stewart, A.L., & Ware, J.E. (1992). Measuring functioning and well-being: The Medical Outcomes Study approach. Durham, NC: Duke University Press.
 
Sullivan, J.J.L., Edgley, K., & Dehoux, E. (1990). A survey of multiple sclerosis. Part 1: Perceived cognitive problems and compensatory strategy use. Canadian Journal of Rehabilitation, 4, 99-105.
 
Tilden, V.P. (1985). Issues of conceptualization and measurement of social support in the construction of nursing theory. Research in Nursing and Health, 8, 199-206.
 
Turnbull, G.K., Hoare, C., Ritvo, P.G., Fisk, J.D., & Murray, T. J. (1993). The assessment of bowel and bladder dysfunction in clinic attending MS patients. Presented at Department of Medicine Research Symposium. Dalhousie University, Halifax, Nova Scotia.
 
Valleroy, M.L., & Kraft, G.H. (1984). Sexual dysfunction in multiple sclerosis. Archives of Physical Medicine and Rehabilitation, 65, 125-128.
 
Veit, C., Ware, J. (1983). The structure of psychological distress and well-being in general populations. Journal of Consulting and Clinical Psychology, 51, 730-732.
 
Vickrey, B.G., Hays, R.D., Harooni, R., Myers, L.W., & Ellison, G.W. (1995). A health-related quality of life measure for multiple sclerosis. Quality of Life Research, 4, 187-206.
 
Ware, J.E., Kosinski, M., Bayliss, M.S., McHorney, C.A., Rogers, W.H. & Raczek, A. (1995). Comparison of methods for scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the Medical Outcomes Study. Medical Care,33 (Suppl), AS264-AS279.