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ALS Depression Inventory (ADI-12)
Please email the author for information about obtaining the instrument:
Supplemental: Amyotrophic Lateral Sclerosis (ALS) and Mithcondrial Disease (Mito)
Short Description of Instrument
The Amyotrophic Lateral Sclerosis Depression Inventory 12 (ADI-12) is a 12 item self-rated questionnaire designed to rate depressive disorders in patients who suffer from ALS. This test describes mood, anhedonia, and energy but does not refer to the motor related symptoms seen in ALS.
The ADI-12 was validated against the structured clinical interview for DSM-IV (SCID), as the gold standard for diagnosis of depression.
Scores range from 12 (the best possible) to 48 (worst possible). Scores between 23 and 29 indicate mild depression and scores over 30 indicate severe
Hammer, E. M., Hacker, S., Hautzinger, M., Meyer, T. D., & Kübler, A. (2008). Validity of the ALS-Depression-Inventory (ADI-12)- A new screening instrument for depressive disorders in patients with amyotrophic lateral sclerosis. J Affect Disord. 109 (2008) 213-219.
Nazem Atassi, Amanda Cook, Cristiana M. E. Pineda, Padmaja Yerramilli-Rao, Darlene Pulley, Merit Cudkowicz. Depression in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2011 March; 12(2): 109-112.


Document last updated February 2018