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Center for Neurologic Study - Bulbar Function Scale (CNS-BFS)
Please visit this website for more information about the instrument: Center for Neurologic Bulbar Function Scale
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Supplemental: Amyotrophic Lateral Sclerosis (ALS)
Short Description of Instrument
The CNS-BFS, a self report scale, is designed to evaluate and monitor bulbar function in ALS patients. It includes three domains: speech, swallowing and salivation. It was validated using an online patient social network. The nine item scale exhibits strong internal reliability and exhibits high sensitivity and specificity.
Each domain is interrogated with three questions which the subject scores from 1-5, resulting in a range of scores from 9-45. A score of 21 identifies 90% of subjects with bulbar dysfunction at a specificity of .97.
Smith RA, Yagi N, Wicks P, Thisted R. Development of a self-report bulbar function scale (CNS-BFS) Neurology. 2011;76(Suppl. 4):A48.
Smith R, Pioro E, Myers K, Sirdofsky M, Goslin K, Meekins G, Yu H, Wymer J, Cudkowicz M, Macklin EA, Schoenfeld D, Pattee G. Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial. Neurotherapeutics. 2017;14(3):762-772. Erratum in: Neurotherapeutics. 2017.
Smith RA, Macklin EA, Myers KJ, Pattee GL, Goslin KL, Meekins GD, Green JR, Shefner JM, Pioro EP. Assessment of bulbar function in amyotrophic lateral sclerosis: validation of a self-report scale (Center for Neurologic Study Bulbar Function Scale). Eur J Neurol. 2018;25(7):907-e66.


Document last updated July 2018