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ALS Functional Rating Scale - Revised (ALSFRS-R)
ALS Functional Rating Scale - Revised (ALSFRS-R)
| Availability |
Please visit this website for more information about the instrument:
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| Classification |
Core: Amyotrophic Lateral Sclerosis (ALS)
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| Short Description of Instrument |
The ALS Functional Rating Scale is a 10-item rating scale that measures the progression of disability in patients with ALS. The ALSFRS assesses patients' levels of self-sufficiency in areas of feeding, grooming, ambulation and communication.
The Revised version was introduced to gather additional information related to sleeping and breathing. It consists of 12 questions with a maximum score of 48 points.
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| Scoring |
Each item is rated on a 4 (0-4) point scale yielding a maximum of 40 points.
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| References |
The ALS C.A.R.E. Program. (2018). Retrieved 11 Jul 2018, from
https://www.outcomes-umassmed.org/ALS/alsscale.aspx. The Amyotrophic Lateral Sclerosis Functional Rating Scale. Assessment of activities of daily living in patients with amyotrophic lateral sclerosis. The ALS CNTF treatment study (ACTS) phase I-II Study Group. Arch Neurol. 1996;53(2):141-147.
Castrillo-Viguera C, Grasso DL, Simpson E, Shefner J, Cudkowicz ME. Clinical significance in the change of decline in ALSFRS-R. Amyotroph Lateral Scler. 2010;11(1-2):178-180.
Cedarbaum JM, Stambler N, Malta E, Fuller C, Hilt D, Thurmond B, Nakanishi A. The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci. 1999;169(1-2):13-21.
Cedarbaum JM, Stambler N. Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials. J Neurol Sci. 1997;152 Suppl 1:S1-S9.
Gordon PH. Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials. Aging Dis. 2013;4(5):295-310.
Gordon PH, Miller RG, Moore DH. ALSFRS-R. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004;5 Suppl 1:90-93
Document last updated July 2019
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