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| Availability |
Please visit this website for more information about the instrument: Rome III/IV Constipation Module
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| Classification |
Supplemental: Parkinson's Disease (PD)
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| Short Description of Instrument |
The Rome III/IV Criteria for Functional Gastrointestinal Disorders was developed via Delphic process and is widely recognized within the Gastrointestinal research community.
The Rome III and IV Criteria Constipation Module provides a consensus definition for a functional constipation diagnosis. It is appropriate for use in both clinical and research settings.
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| Comments/Special Instructions |
The Rome III and IV Diagnostic Questionnaire for Functional Gastrointestinal Disorders in Adults (R3DQ and R4DQ) is comprised of the Rome III/IV diagnostic criteria in question form that can be understood and reported by patients and research participants. The R3/4DQ intended uses are to provide inclusion criteria for clinical research studies, to serve as case definitions for epidemiological surveys, and to assist clinicians in arriving at a provisional diagnosis.
The Rome III/IV questionnaires for adult and pediatric patients/participants are available upon request. Please the Rome Foundation Copyright and Licensing page for more information.
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| Scoring and Psychometric Properties |
Scoring: Functional constipation is diagnosed when presence of two or more of the listed symptoms are experienced for the previous 3 months with their onset beginning at least six months prior.
Psychometric Properties: The Rome IV criteria have been reported to have a sensitivity of 33.9% and specificity of 94.5%% for functional constipation, excluding opioid-induced constipation and irritable bowel syndrome when tested in adult gastroenterology clinic patients. When including opioid-induced constipation and irritable bowel syndrome, the reported sensitivity was 70.5% and the specificity was 93.1% (Palsson et al., 2016).
Specificity and test-retest agreement of the Rome III Criteria Constipation Module were reported as 96.5% and 93.3%, respectively.
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| References |
Key References:
Palsson OS, Turner MJ, Levy RL, Feld AD, Korff MV, Drossman DA, Whitehead WE. The ROME III Questionnaire Functional Constipation Module As a Constipation Severity Scale. Gastroenterology. 2008;134(4, Supplement 1):A421.
Drossman DA (ed.) et al. Rome IV Functional GI Disorders - Disorders of Gut-Brain Interaction. pp 1-1741 Raleigh NC, Rome Foundation 2016. Available at: https://theromefoundation.org/rome-iv/rome-iv-journal-articles/
Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV. Gastroenterology 2016;150:1262-1279.
Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R. Bowel Disorders. Gastroenterology. 2016 Feb 18:S0016-5085(16)00222-5.
Additional References:
Lacy BE, Mearin F, Chang L, Chey WD, Lembo AJ, Simren M, Spiller R. Bowel Disorders. Gastroenterology 2016;150(6):1393-1407.E5.
Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130:1480-1491.
Palsson OS, Whitehead W, Tornblom H, Sperber AD, Simren M. Prevalence of Rome IV Functional Bowel Disorders Among Adults in the United States, Canada, and the United Kingdom. Gastroenterology. 2020 Apr;158(5):1262-1273.e3
Palsson OS, Whitehead WE, van Tilburg MAL, Chang L, Chey W, Crowell MD, Keefer L, Lembo AJ, Parkman HP, Rao SSC, Sperber A, Spiegel B, Tack J, Vanner S, Walker LS, Whorwell P, Yang Y. Development and validation of the Rome IV diagnostic questionnaire for adults. Gastroenterology 2016;150:1481-1491.
Rome Foundation. (2022) Development and Validation of Rome III Questionnaire - 2006. Available from: https://theromefoundation.org/programs-projects/research-program/development-and-validation-of-rome-iii-questionnaire-2006/. Accessed 11April2022.
Rome Foundation. (2022) Rome IV Criteria for Functional Gastrointestinal Disorders. Available from: https://theromefoundation.org/rome-iv/rome-iv-criteria/. Accessed 08April2022.
Document last updated August 2022
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