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Apathy Motivation Index Caregiver Version (AMI-CG)
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Supplemental: Parkinson's Disease (PD)
Short Description of Instrument
The Apathy Motivation Index Caregiver Version (AMI-CG) is an 18 item caregiver reported index that assesses apathy in the behavioral activation (BA), emotional sensitivity (ES), and social motivation (SM) domains over the previous two weeks. It was adapted from the Lille Apathy Rating Scale (LARS).
Scoring and Psychometric Properties
Total AMI-CG score correlated positively with Lille Apathy Rating Scale - caretaker index (LARS-i) overall score (r = 0.72, P < 0.01); internal reliability was good to acceptable (Cronbach's a overall = 0.85, a BA = 0.85, a SM = 0.70, a ES = 0.79) in PD, Alzheimer's disease, subjective cognitive impairment and limbic encephalitis (Klar et al., 2021). ROC analysis with LARS-i as good standard showed good accuracy (sensitivity = 0.82, specificity = 0.76, area under the curve (AUC) = 0.85).
Strengths: Multidimensional assessment of apathy; take less than 5 minutes to complete.
Weaknesses: Limited use in PD. May overestimate apathy.
Key References:
Klar VS, Ang YS, Lockwood P, Attaallah B, Dickson S, Drew D, Kienast A, Maio MR, Plant O, Slavkova E, Toniolo S, Zambellas R, Irani SR, Husain M. Assessment of apathy in neurological patients using the Apathy Motivation Index caregiver version. J Neuropsychol. 2021 Sep 16. doi: 10.1111/jnp.12262. Epub ahead of print.
Ang YS, Lockwood PL, Kienast A, Plant O, Drew D, Slavkova E, Tamm M, Husain M. Differential impact of behavioral, social, and emotional apathy on Parkinson's disease. Ann Clin Transl Neurol. 2018 Aug 14;5(10):1286-1291.
Additional Reference:
Ang YS, Lockwood P, Apps MA, Muhammed K, Husain M. Distinct Subtypes of Apathy Revealed by the Apathy Motivation Index. PLoS One. 2017 Jan 11;12(1):e0169938.
Document last updated August 2022