CDE Detailed Report

Disease: Chiari I Malformation
Sub-Domain: Imaging Diagnostics
CRF: Chiari I Malformation Imaging

Displaying 1 - 33 of 33
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C58514 Empty sella turcica present indicator EmptySellaTurcicaPresentInd The indicator related to presence of empty sella turcica. The indicator related to presence of empty sella turcica. Empty Sella turcica present? No;Yes No;Yes Alphanumeric

Pituitary height:
I: normal appearance—the superior aspect of the pituitary gland was either convex or flat
II: mild (loss of pituitary height h > 2/3 of the sella height H
III: moderate (1/3 H IV: severe (hV: empty sella if the sella turcica was enlarged and no pituitary parenchyma was observable
(where h denotes the pituitary height and H denotes the height of the sella turcica.
Define h as the minimal pituitary height in the mid-sagittal plane
Define H as either the maximal depth of the sella turcica in the mid-sagittal plane as measured to the tuberculum sellae OR to the limbus sphenoidale- the latter may be favored due to ease of identification)

Pituitary dorsal contour:
Convex, Flat, Concave (as viewed from above)

Adult;Pediatric Exploratory 1.00 2016-06-01 15:29:11.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21737 Imaging posterior cranial fossa soft tissue clivo-axial angle (CXA) measurement ImgPosCraFosSofTissCXAMeasr The measurement as related to soft tissue clivo-axial angle (CXA). The measurement as related to soft tissue clivo-axial angle (CXA). Soft Tissue Clivo-axial Angle (CXA) Numeric Values

Draw a line from the spheno-occipital synchondrosis (or mid-point of the clivus if not visible in the adult subject) to the posterior most point on the ventral dura posterior to the odontoid process (inferior half of the clivus). Draw another line from the posterior inferior aspect of C2 to the posterior-most point on the ventral dura. The angle between these lines is the soft tissue CXA. (Best measured on T2 sagittal midline MRI)

Adult;Pediatric Exploratory 1.00 2016-06-01 15:07:36.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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0 360 Degrees
C21748 Imaging posterior cranial fossa foramen magnum diameter measurement ImgPosCraFosForMagDiaMeasr The measurement as related to distance from basion to opisthion The measurement as related to distance from basion to opisthion Foramen Magnum diameter Numeric Values

Distance from basion to opisthion.

Adult;Pediatric Supplemental 1.00 2016-06-01 15:17:57.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C58515 Greatest transverse spinal cord diameter measurement GrtestTransvSpinlCordDiamMeasr Greatest transverse diameter of spinal cord on T2-WI as measured on MRI in the axial plane (in mm). Greatest transverse diameter of spinal cord on T2-WI as measured on MRI in the axial plane (in mm). Greatest transverse diameter of the spinal cord Numeric Values Adult;Pediatric Supplemental 1.00 2018-05-08 13:07:26.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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millimeter
C21738 Imaging posterior cranial fossa bone clivo-axial angle (CXA) measurement ImgPosCraFosBonCXAMeasr The measurement as related to bone clivo-axial angle (CXA). The measurement as related to bone clivo-axial angle (CXA). Bone Clivo-axial Angle (CXA) Numeric Values

Draw a line from the sphenooccipital synchondrosis to the basion (inferior half of the clivus). Draw another line from the posterior inferior aspect of C2 to the posterior-most point on the odontoid process. The angle between these lines is the bony CXA. (best measured on CT)

Adult;Pediatric Exploratory 1.00 2016-06-01 15:07:36.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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0 360 Degrees
C21749 Imaging posterior cranial fossa superior posterior fossa length measurement ImgPosCraFosSupPosFosLenMeasr The measurement as related to distance from dorsum sella to internal occipital protuberance The measurement as related to distance from dorsum sella to internal occipital protuberance Superior Posterior fossa length Numeric Values

Distance from dorsum sella to internal occipital protuberance.

Adult;Pediatric Supplemental 1.00 2016-06-01 15:19:21.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21728 Imaging cerebellar tonsil lowest position measurement ImgCerTonLowPosMeasr The measurement related to lowest tonsillar position relative to foramen magnum. The measurement related to lowest tonsillar position relative to foramen magnum. Lowest tonsillar position Numeric Values

Define foramen magnum using midline image. Draw line from basion to opisthion. Define basion and opisthion as the confluence of cortical bone (most inferior). Ventral most point on opisthion. Measure tonsillar position perpendicular to that line. Tonsillar measurement may be taken parasagittally to assure the largest possible number is recorded. Record negative number for tonsil position above line. Based on T1 sagittal or coronal MRI.

Barkovich AJNR 7(5) 795 1986;Smith JNS 119(3) 812 2013 Adult;Pediatric Core 1.00 2016-06-01 14:01:44.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C58516 Greatest transverse thecal sac diameter measurement GrtestTransvThecalSacDiamMeasr Greatest transverse diameter of thecal sac on T2-WI as measured on MRI in the axial plane (in mm). Greatest transverse diameter of thecal sac on T2-WI as measured on MRI in the axial plane (in mm). Greatest transverse diameter of the thecal sac Numeric Values Adult;Pediatric Supplemental 1.00 2018-05-08 13:07:26.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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millimeter
C21739 Imaging posterior cranial fossa pB-C2 measurement ImgPosCraFospBC2Measr The measurement as related to distance from dura to the line drawn from the basion to the posterior inferior edge of the C2 vertebra The measurement as related to distance from dura to the line drawn from the basion to the posterior inferior edge of the C2 vertebra pB-C2 Numeric Values

Draw a line from the basion to the posterior inferior most point of C2. Measure the perpendicular distance from the posterior most point on the ventral dura posterior to the odontoid process to the first line (perpendicular).

Grabb and Oakes Adult;Pediatric Supplemental 1.00 2016-06-01 15:09:27.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21750 Imaging posterior cranial fossa tentorial angle measurement ImgPosCraTenAngMeasr The measurement as related to the angle between line drawn along the tentorium with line drawn from the internal occipital protuberance to the opisthion; Alternative measurement: angle between line drawn paralell to clivus and line drawn paralell to tentorium, independent of orientation of occipital bone The measurement as related to the angle between line drawn along the tentorium with line drawn from the internal occipital protuberance to the opisthion; Alternative measurement: angle between line drawn paralell to clivus and line drawn paralell to tento Tentorial angle Numeric Values

Decide which measurement, favor to the clival measurement.
0-360°; Angle between line drawn along the tentorium with line drawn from the internal occipital protuberance to the opisthion.

Adult;Pediatric Supplemental 1.00 2016-06-01 15:20:18.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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0 360 Degrees
C21729 Imaging cerebellar tonsil right position measurement ImgCerTonRtPosMeasr The measurement related to right tonsillar position relative to foramen magnum. The measurement related to right tonsillar position relative to foramen magnum. Position of right cerebellar tonsil Numeric Values

Define foramen magnum using midline image. Draw line from basion to opisthion. Define basion and opisthion as the confluence of cortical bone (most inferior). Ventral most point on opisthion. Measure tonsillar position perpendicular to that line parasagittally through the tip of the right tonsil. Tonsillar measurement should be taken to assure the largest possible number is recorded. Record negative number for tonsil position above line. Based on T1 sagittal or coronal MRI.

Barkovich AJNR 7(5) 795 1986;Smith JNS 119(3) 812 2013 Adult;Pediatric Core 1.00 2016-06-01 14:01:44.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
C21740 Imaging posterior cranial fossa basion axial interval measurement ImgPosCraFosBAIntrvlMeasr The measurement as related to distance from tip of basion to posterior axial line The measurement as related to distance from tip of basion to posterior axial line Basion Axial Interval (BAI, Harris Measurement) Numeric Values

Draw a linge from the psoteriror inferior most point on C2 to the most posterior point of the odontoid process. Extend this lin in a rpstral direction. Measure the perpendicular distance from the basion to the line. (Best measured on bony imaging such as CT)

Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21751 Imaging spine anomaly congenital fusion cervical vertebrae present indicator ImgSpiAnoConFusCerVerPreInd The indicator related to the congenital fusion of cervical vertebrate on the imaging spinal anomalies. The indicator related to the congenital fusion of cervical vertebrate on the imaging spinal anomalies. Congenital Fusion of cervical vertebrae No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:21:42.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21730 Imaging cerebellar tonsil left position measurement ImgCerTonLftPosMeasr The measurement related to left tonsillar position relative to foramen magnum. The measurement related to left tonsillar position relative to foramen magnum. Position of left cerebellar tonsil Numeric Values

Define foramen magnum using midline image. Draw line from basion to opisthion. Define basion and opisthion as the confluence of cortical bone. Ventral most point on opisthion. Measure tonsillar position perpendicular to that line parasagittally through the tip of the left tonsil. Tonsillar measurement should be taken to assure the largest possible number is recorded. Record negative number for tonsil position above line. Based on T1 sagittal or coronal MRI.

Barkovich AJNR 7(5) 795 1986;Smith JNS 119(3) 812 2013 Adult;Pediatric Core 1.00 2016-06-01 14:01:44.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
C21741 Imaging posterior cranial fossa basion axial interval extension measurement ImgPosCraFosBAIntrvlExtMeasr The measurement as related to distance from tip of basion to posterior axial line while in extension The measurement as related to distance from tip of basion to posterior axial line while in extension BAI in extension Numeric Values Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
C21752 Imaging spine anomaly atlas assimilation present indicator ImgSpiAnoAtlAssPreInd The indicator related to the atlas assimilation on the imaging spinal anomalies. The indicator related to the atlas assimilation on the imaging spinal anomalies. Atlas assimilation No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:21:42.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21731 Imaging cerebellar tonsil shape type ImgCerTonShaTyp The type as related to the relative tonsil shape reported. The type as related to the relative tonsil shape reported. Shape of cerebellar tonsils Pegged;Intermediate;Rounded Pegged;Intermediate;Rounded Alphanumeric

Choose the relative shape of the cerebellar tonsils as rounded, pegged or intermediate between the two; see diagram for guidance

Adult;Pediatric Exploratory 1.00 2016-06-01 14:01:44.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21742 Imaging posterior cranial fossa basion axial interval flexion measurement ImgPosCraFosBAIntrvlFleMeasr The measurement as related to distance from tip of basion to posterior axial line while in flexion The measurement as related to distance from tip of basion to posterior axial line while in flexion BAI in flexion Numeric Values Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
C21753 Imaging spine anomaly other craniocervical present indicator ImgSpiAnoOthrCraPreInd The indicator related to presence of other craniocervical abnormalities on the imaging spinal anomalies. The indicator related to presence of other craniocervical abnormalities on the imaging spinal anomalies. Presence of other craniocervical abnormalities No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:21:42.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21732 Imaging syrinx present indicator ImgSyrPreInd The indicator related to presence of syrinx within the spinal cord measuring greater than 3 mm in axial plane T1 imaging The indicator related to presence of syrinx within the spinal cord measuring greater than 3 mm in axial plane T1 imaging Syrinx Present No;Yes No;Yes Alphanumeric

Choose Yes/No: 'Yes' if fluid signal (CSF) is present within the spinal cord measuring greater than 3 mm in axial plane imaging

Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-06-01 14:42:50.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21743 Imaging posterior cranial fossa basion dens interval measurement ImgPosCraFosBDIntrvlMeasr The measurement as related to distance from basion to tip of odontoid The measurement as related to distance from basion to tip of odontoid Basion-Dens Interval (BDI) Numeric Values

Distance from basion to tip of odontoid (best measured on bony imaging such as CT)

Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21754 Imaging spine anomaly tethered cord present indicator ImgSpiAnoTetCorPreInd The indicator related to presence of tethered cord on the imaging spinal anomalies The indicator related to presence of tethered cord on the imaging spinal anomalies Tethered cord present No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:21:42.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21733 Imaging syrinx length spinal segment count ImgSyrLenSpiSegCou The number of spinal segments for length of syrinx as measure on sagittal MRI scan The number of spinal segments for length of syrinx as measure on sagittal MRI scan Length of hydrosyringomyelia Numeric Values

Length of syrinx as measured on sagittal MRI scan; reported in number of spinal segments (1 to 29). e.g. – a syrinx extending from C2 to T5 will measure 11 segments. Record 11.
[The minimal value of this field when fluid is present in the spinal cord (i.e. #5 is yes) is set to "1." A "segment" is defined as equal to or greater than the half the height of the corpus of the adjoining vertebral bodies at the mid-sagittal plane. Example: hydrosyringomyelia extending from just caudal to the mid-point of the C3 vertebral body to just rostral to the mid-point of the C5 vertebral body would be assigned a value of "2."]

Adult;Pediatric Supplemental 1.00 2016-06-01 14:59:35.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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1 29
C21744 Imaging posterior cranial fossa basion dens interval extension measurement ImgPosCraFosBDIntrvlExtMeasr The measurement as related to distance from basion to tip of odontoid in extension The measurement as related to distance from basion to tip of odontoid in extension BDI in extension Numeric Values Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21755 Imaging spine anomaly spinal dysraphism present indicator ImgSpiAnoSpiDysPreInd In this context, we define spina bifida occulta as non-fusion of the posterior spinal elements without evidence of any other abnormality of the spinal cord or dura In this context, we define spina bifida occulta as non-fusion of the posterior spinal elements without evidence of any other abnormality of the spinal cord or dura Spinal Dysraphism present? (excluding spina bifida occulta) No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:21:42.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21734 Imaging syrinx highest level spinal segment number ImgSyrLenSpiSegNum The number as related to the highest level of syrinx, reported in terms of most superior spinal segment along syrinx The number as related to the highest level of syrinx, reported in terms of most superior spinal segment along syrinx Highest level of syrinx Alphanumeric

Identify location of single segment most superior e.g., C2. Reported in number of spinal segments.

Adult;Pediatric Supplemental 1.00 2016-06-01 14:59:35.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations 255

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C21745 Imaging posterior cranial basion dens axial interval flexion measurement ImgPosCraFosBDIntrvlFleMeasr The measurement as related to distance from basion to tip of odontoid in flexion The measurement as related to distance from basion to tip of odontoid in flexion BDI in flexion Numeric Values Adult;Pediatric Exploratory 1.00 2016-06-01 15:10:37.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
C21756 Imaging other incidental finding text ImgOthrIncFindTxt The free-text field related to report of any additional incidental findings (e.g.- Meniongioma, arachnoid cyst, tumor, stroke). The free-text field related to report of any additional incidental findings (e.g.- Meniongioma, arachnoid cyst, tumor, stroke). Incidental imaging findings Alphanumeric Adult;Pediatric Exploratory 1.00 2016-06-01 15:28:08.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations 4000

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C21735 Imaging syrinx lowest level spinal segment number ImgSyrLowLvlSpiSegNum The number as related to the lowest level of syrinx, reported in terms of most inferior spinal segment along syrinx The number as related to the lowest level of syrinx, reported in terms of most inferior spinal segment along syrinx Lowest level of syrinx Alphanumeric

Identify location of single segment most inferior e.g., T5. Reported in number of spinal segments

Adult;Pediatric Supplemental 1.00 2016-06-01 15:04:38.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations 255

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C21746 Imaging posterior cranial fossa clivus length measurement ImgPosCraFosCliLenMeasr The measurement as related to distance from dorsum sella to basion on midsagittal MRI The measurement as related to distance from dorsum sella to basion on midsagittal MRI Clivus Length Numeric Values

Distance from dorsum sella to basion on midsagittal image.

Alperin et al Neurosurg 75(5) 515 2014 Adult;Pediatric Supplemental 1.00 2016-06-01 15:16:13.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21757 Imaging hydrocephalus ventriculomegaly finding indicator ImgHydVenFindInd The indicator related to presence of hydrocephalus/ventriculomegaly. The indicator related to presence of hydrocephalus/ventriculomegaly. Hydrocephalus/Ventriculomegaly No;Yes No;Yes Alphanumeric

Choose Yes / No

Adult;Pediatric Exploratory 1.00 2016-06-01 15:29:11.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C21736 Imaging syrinx width measurement ImgSyrWidMeasr Greatest transverse diameter of hydrosyringomyelia on T2-WI as measured on MRI in the axial plane (in mm). Greatest transverse diameter of hydrosyringomyelia on T1-WI as measured on MRI in the axial plane (in mm). Maximum transverse diameter of hydrosyringomyelia Numeric Values

Greatest transverse diameter of hydrosyringomyelia on T1-WI as measured on MRI in the axial plane (in mm).

Adult;Pediatric Supplemental 1.00 2016-06-01 15:06:23.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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C21747 Imaging posterior cranial fossa supraoccipital length measurement ImgPosCraFosCliSupLenMeasr The measurement as related to distance from opisthion to internal occipital protuberance on midsagittal MRI The measurement as related to distance from opisthion to internal occipital protuberance on midsagittal MRI Supraoccipital Length Numeric Values

Distance from opisthion to the most anterior aspect of the internal occipital protuberance on midsagittal image.

Alperin et al Neurosurg 75(5) 515 2014 Adult;Pediatric Supplemental 1.00 2016-06-01 15:16:13.0 Chiari I Malformation Imaging Imaging Diagnostics Assessments and Examinations

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Millimeters
CSV