CDE Detailed Report

Disease: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Subdomain Name: Quality of Life/Patient Reported Outcomes
CRF: Short Form 36-Item Health Survey (SF-36)

Displaying 1 - 36 of 36
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C08507 36-item Short Form Health Survey (SF-36) - Health limited climbing one stair score SF36HlthLmtClmb1StairScore Score of surveyee-reported limited climbing one flight of stairs due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited climbing one flight of stair due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Climbing one flight of stairs? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08518 36-item Short Form Health Survey (SF-36) - Less accomplished emotional problems indicator SF36LesAccompEmotProbInd Indicator for surveyee-reported less accomplishment as a result of emotional problems during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported less accomplishment as a result of emotional problems during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, have you: Accomplished less than you would like? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious)? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08529 36-item Short Form Health Survey (SF-36) - Times worn out score SF36TimesWornOutScore Score of times feeling worn out during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling worn out during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Did you feel worn out? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08508 36-item Short Form Health Survey (SF-36) - Health limited bending kneeling stooping score SF36HlthLmtBndKnlStpScore Score of surveyee-reported limited bending, kneeling, or stooping due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited bending, kneeling, or stooping due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Bending, kneeling, or stooping? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08519 36-item Short Form Health Survey (SF-36) - Work not carefully emotional problems indicator SF36WkNotCarefulEmotProbInd Indicator for surveyee-reported doing work or other activities not as carefully as usual as a result of emotional problems during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported doing work or other activities not as carefully as usual during the past 4 weeks as a result of any emotional problems as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, you: Didn't do work or other activities as carefully as usual? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious)? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08530 36-item Short Form Health Survey (SF-36) - Times happy score SF36TimesHppyScore Score of times being a happy person during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times being a happy person during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Have you been a happy person? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08509 36-item Short Form Health Survey (SF-36) - Health limited walking miles score SF36HlthLmtWlkSvrlMilScore Score of surveyee-reported limited walking more than one mile due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited walking more than one mile score due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Walking more than a mile? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08520 36-item Short Form Health Survey (SF-36) - Interfered social activities physical emotional problems score SF36InterfSocPhyEmotScore Score of interfered normal social activities with family, friends, neighbors, or groups due to physical health or emotional problems during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of interfered normal social activities with family, friends, neighbors, or groups due to physical health or emotional problems during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, to what extent has your physical health or emotional problems interfered with your normal social activities with family, friends, neighbors, or groups? 1;2;3;4;5 Not at all;Slightly;Moderately;Quite a bit;Extremely Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08531 36-item Short Form Health Survey (SF-36) - Times tired score SF36TimesTiredScore Score of times feeling tired during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling tired during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Did you feel tired? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08510 36-item Short Form Health Survey (SF-36) - Health limited walking several blocks score SF36HlthLmtWlkSvrlBlckScore Score of surveyee-reported limited walking several blocks due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited walking several blocks due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Walking several blocks? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08521 36-item Short Form Health Survey (SF-36) - Bodily pain score SF36BodyPainScore Score of bodily pain during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of bodily pain during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much bodily pain have you had during the past 4 weeks? 1;2;3;4;5;6 None;Very mild;Mild;Moderate;Severe;Very severe Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08532 36-item Short Form Health Survey (SF-36) - Times interfered social physical or emotional score SF36TimesInterSocPhyEmtScore Score of times physical health or emotional problems interfered with social activities (like visiting with friends, relatives, etc) during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times social activities (like visiting with friends, relatives, etc) interfered by physical health or emotional problems interfered during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, how much of the time has your physical health or emotional problems interfered with your social activities (like visiting friends, relatives, etc.)? 1;2;3;4;5 All of the time;Most of the time;Some of the time;A little of the time;None of the time Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08511 36-item Short Form Health Survey (SF-36) - Health limited walking one block score SF36HlthLmtWlk1BlckScore Score of surveyee-reported limited walking one block due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited walking one block due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Walking one block? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08522 36-item Short Form Health Survey (SF-36) - Pain interfere work score SF36PainInterfWrkScore Score of bodily pain interfering with work (in home and outside) during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of interfered work (in home and outside) by bodily pain during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, how much did pain interfere with your normal work (including both work outside the home and housework)? 1;2;3;4;5 Not at all;A little bit;Moderately;Quite a bit;Extremely Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08500 36-item Short Form Health Survey (SF-36) - General health score SF36GenHlthScore Score of surveyee-reported general health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported general health as a part of version 1.0 of 36-item Short Form Health Survey (SF-36) In general, would you say your health is 1;2;3;4;5 Excellent;Very good;Good;Fair;Poor Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08533 36-item Short Form Health Survey (SF-36) - Sick easier score SF36SckEasierScore Score of how true or false surveyee perceived the statement: I seem to get sick a little easier than other people, as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of how true or false surveyee perceived the statement: getting sick a little easier than other people as part of version 1.0 of 36-item Short Form Health Survey (SF-36) I seem to get sick a little easier than other people 1;2;3;4;5 Definitely true;Mostly true;Don't know;Mostly false;Definitely false Numeric Values

Text before question group: How TRUE or FALSE is each of the following statements for you? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08512 36-item Short Form Health Survey (SF-36) - Health limited bathing dressing score SF36HlthLimtBthDrssScore Score of surveyee-reported limited bathing or dressing due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited bathing or dressing due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Bathing or dressing yourself? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08523 36-item Short Form Health Survey (SF-36) - Times pep score SF36TimesPepScore Score of times feeling full of pep during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling full of pep during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Did you feel full of pep? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08502 36-item Short Form Health Survey (SF-36) - Now heath score SF36NowHlthScore Score of surveyee-reported present general heath compared to a year ago as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported heath compared to a year ago as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Compared to one year ago, how would you rate your health in general now? 1;2;3;4;5 Much better now than one year ago;Somewhat better now than one year ago;About the same;Somewhat worse now than one year ago;Much worse now than one year ago Numeric Values

This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08534 36-item Short Form Health Survey (SF-36) - Healthy as anybody score SF36HlthyAsAnybodyScore Score of how true or false surveyee perceived the statement: I am as healthy as anybody I know, as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of how true or false surveyee perceived the statement as part of version 1.0 of 36-item Short Form Health Survey (SF-36): I am as healthy as anybody I know I am as healthy as anybody I know 1;2;3;4;5 Definitely true;Mostly true;Don't know;Mostly false;Definitely false Numeric Values

Text before question group: How TRUE or FALSE is each of the following statements for you? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08513 36-item Short Form Health Survey (SF-36) - Cut time on work activities physical health indicator SF36CutTimeWrkActPhyHlthIndCd Indicator for surveyee-reported cut down time on work or other activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported cut down of time on work or other activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, have you: Cut down on the amount of time you spent on work or other activities? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08524 36-item Short Form Health Survey (SF-36) - Times nervous score SF36TimesNervsScore Score of times being a very nervous person during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times being a very nervous person during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Have you been a very nervous person? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08503 36-item Short Form Health Survey (SF-36) - Health limited vigorous activities score SF36HlthLmtVigorActScore Score of surveyee-reported limited vigorous activities due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited vigorous activities due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Vigorous activities, such as running, lifting heavy objects, participating in strenuous sports? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08535 36-item Short Form Health Survey (SF-36) - Expect worse health score SF36ExpWorsHlthScore Score of how true or false surveyee perceived the statement: I expect my health to get worse, as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of how true or false surveyee perceived the statement as part of version 1.0 of 36-item Short Form Health Survey (SF-36): I expect my health to get worse I expect my health to get worse 1;2;3;4;5 Definitely true;Mostly true;Don't know;Mostly false;Definitely false Numeric Values

Text before question group: How TRUE or FALSE is each of the following statements for you? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08514 36-item Short Form Health Survey (SF-36) - Less accomplished physical health indicator SF36LesAccompPhyHlthInd Indicator for surveyee-reported less accomplishment as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported less accomplishment as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, have you: Accomplished less than you would like? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08525 36-item Short Form Health Survey (SF-36) - Times down score SF36TimesDownScore Score of times feeling so down in the dumps that nothing could cheer up during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling so down in the dumps that nothing could cheer up during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Have you felt so down in the dumps that nothing could cheer you up? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08504 36-item Short Form Health Survey (SF-36) - Health limited moderate activities score SF36HlthLmtModActScore Score of surveyee-reported limited moderate activities due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited moderate activities due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Moderate activities, such as moving a table, pushing a vacuum cleaner, bowling, or playing golf? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08536 36-item Short Form Health Survey (SF-36) - Excellent health score SF36ExcelHlthScore Score of how true or false surveyee perceived the statement: My health is excellent, as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of how true or false surveyee perceived the statement as part of version 1.0 of 36-item Short Form Health Survey (SF-36): My health is excellent My health is excellent 1;2;3;4;5 Definitely true;Mostly true;Don't know;Mostly false;Definitely false Numeric Values

Text before question group: How TRUE or FALSE is each of the following statements for you? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08515 36-item Short Form Health Survey (SF-36) - Limited work activities physical health indicator SF36LmtWrkActPhyHlthInd Indicator for surveyee-reported limited work or activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported limited work or activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, you: Were limited in the kind of work or other activities? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08526 36-item Short Form Health Survey (SF-36) - Times calm peaceful score SF36TimesCalmPcfulScore Score of times feeling calm and peaceful during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling calm and peaceful during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Have you felt calm and peaceful? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08505 36-item Short Form Health Survey (SF-36) - Health limited carrying groceries score SF36HlthLmtCrryGrocryScore Score of surveyee-reported limited lifting or carrying groceries due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited lifting or carrying groceries due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Lifting or carrying groceries? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08516 36-item Short Form Health Survey (SF-36) - Difficulty work activities physical health indicator SF36DiffcltWrkActPhyHlthInd Indicator for surveyee-reported difficulty performing work or other activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported difficulty performing work or other activities as a result of physical health during past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, have you: Had difficulty performing the work or other activities (for example, it took extra effort)? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08527 36-item Short Form Health Survey (SF-36) - Times energy score SF36TimesEnrgyScore Score of times having a lot of energy during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times having a lot of energy during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Did you have a lot of energy? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08506 36-item Short Form Health Survey (SF-36) - Health limited climbing several stairs score SF36HlthLmtClmbSvrlStairScore Score of surveyee-reported limited climbing several flights of stairs due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of surveyee-reported limited climbing several flights of stairs due to physical health as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Does your health now limit you in: Climbing several flights of stairs? 1;2;3 Yes, limited a lot;Yes, limited a little;No, not limited at all Numeric Values

Text before question group: The following items are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08517 36-item Short Form Health Survey (SF-36) - Cut time on work activities emotional problems indicator SF36CutTmeWrkActEmotProbInd Indicator for surveyee-reported cut down time on work or other activities as a result of emotional problems during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Indicator for surveyee-reported cut down of time on work or other activities as a result of emotional problems during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) During the past 4 weeks, have you: Cut down on the amount of time you spent on work or other activities? 1;2 Yes;No Alphanumeric

Text before question group: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious)? This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 16:57:17.79 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

C08528 36-item Short Form Health Survey (SF-36) - Times downhearted blue score SF36TimesDownBlueScore Score of times feeling downhearted and blue during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) Score of times feeling downhearted and blue during the past 4 weeks as part of version 1.0 of 36-item Short Form Health Survey (SF-36) How much of the time during the past 4 weeks: Have you felt downhearted and blue? 1;2;3;4;5;6 All of the time;Most of the time;A good bit of the time;Some of the time;A little of the time;None of the time Numeric Values

Text before question group: These questions are about how you feel and how things have been with you during the past 4 weeks. For each question, please give the one answer that comes closest to the way you have been feeling. How much of the time during the past 4 weeks... This CDE captures data from SF-36 version 1.0, with permission from the RAND Corporation. Scoring and validation differ for editions by the RAND Corporation (http://www.rand.org) and by the National Multiple Sclerosis Society (NMSS, http://www.nationalmssociety.org) for Multiple Sclerosis Quality of Life instruments. Questions and values for SF-36 version 2.0 differ from version 1.0. Separate permission must be obtained from QualityMetric Inc. (http://www.sf-36.org) to use that instrument.

SF-36 version 1.0 is reproduced (in its entirety) with permission from the RAND Corporation. Copyright by the RAND Corporation. RAND's permission to reproduce the survey is not an endorsement of the products, services, or other uses in which the survey appears or is applied. Hays, RD (1994). The Medical Outcomes Study (MOS) Measures of Patient Adherence. Retrieved April 19, 2004, from the RAND Corporation web site: http://www.rand.org/health/surveys_tools/mos/mos_core_36item.html Adult Supplemental-Highly Recommended 3.00 2013-07-22 12:47:20.623 Short Form 36-Item Health Survey (SF-36) Quality of Life/Patient Reported Outcomes Outcomes and End Points

Single Pre-Defined Value Selected

CSV