CDE Detailed Report
Disease: system
Subdomain Name: Laboratory Tests and Biospecimens%2FBiomarkers
CRF: files
Displaying 51 - 68 of 68
Subdomain Name: Laboratory Tests and Biospecimens%2FBiomarkers
CRF: files
Displaying 51 - 68 of 68
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C12268 | Immunohistochemical stain used muscle biopsy and autopsy type | ImmhistchmclStnUseMuscBpAp | Which immunohistochemical stains were used on muscle biopsy? | Which immunohistochemical stains were used on muscle biopsy? | Which immunohistochemical stains were used? | Myosin immunohistochemistry;Dystrophin panel;Other stains for limb-girdle or congenital muscular dystrophy;Inflammatory myopathy panel | Myosin immunohistochemistry;Dystrophin panel;Other stains for limb-girdle or congenital muscular dystrophy;Inflammatory myopathy panel | Alphanumeric |
Choose all that apply. If dystrophin panel, Other stains for limb-girdle or congenital muscular dystrophy, or Inflammatory myopathy panel were answered for "Which immunohistochemical stains were performed?", specify stains used. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C12231 | Laboratory name | LabName | Name of laboratory where assessment was performed | Name of laboratory where assessment was performed | Name of laboratory where pathology was performed | Alphanumeric |
Record the laboratory name where pathology was performed |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12519 | Myofiber degeneration severity status | MyofibDegenSeverStat | Severity of the Myofiber degeneration muscle diagnostic abnormalities | Severity of the Myofiber degeneration muscle diagnostic abnormalities | Myofiber degeneration | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
No instructions available |
No references available | Adult | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12245 | Symptom presentation type | SymptmPresentTyp | Symptoms participant/ subject shows at presentation | Symptoms participant/ subject shows at presentation | Symptoms at presentation | Weakness;Hypotonia (floppiness);Muscle pain;Cardiac disease;Central nervous system disease;Unknown | Weakness;Hypotonia (floppiness);Muscle pain;Cardiac disease;Central nervous system disease;Unknown | Alphanumeric |
Check all that apply. |
No references available | Adult;Pediatric | Supplemental | 3.10 | 2017-05-12 12:45:20.0 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C12258 | Biopsy and autopsy central cores type | BpApCentrlCoreTyp | The composition of the central cores | The composition of the central core | Central cores, Specify | Structured;Unstructured | Structured;Unstructured | Alphanumeric |
Only answered if "Central cores" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17898 | Laboratory director unknown indicator | LabDirectorUnknownInd | Indicator of unknown laboratory director | Indicator of unknown laboratory director | Name of laboratory director | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12269 | Biopsy and autopsy immunohistochemical immunofluorescence assays performed | BpApImnhschmImnflrsncAssyPerf | List of stains used | List of stains used | Immunohistochemical/ Immunofluorescence assays performed | Alphanumeric |
List the stains used based upon answers in question 3 |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12232 | Laboratory director name | LabDirectorName | Name of laboratory director where assessment was performed | Name of laboratory director where assessment was performed | Name of laboratory director | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12520 | Specimen type 1 fiber muscle biopsy percent result number | SpecTyp1FibMuscBpPctResltNum | Result for type 1 fiber muscle biopsy percent | Result for type 1 fiber muscle biopsy percent | Numeric Values |
Only record Type 1 fiber percentage if Type 1 predominance is completed |
No references available | Adult | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12247 | Biopsy and Autopsy tissue collection method type | BpApTissCollMethdTyp | The type of method used for collection of the tissue specimen | The type of method used for collection of the tissue specimen | Biopsy method | Punch biopsy;Blister biopsy;Open biopsy;Open;Needle | Punch biopsy;Blister biopsy;Open biopsy;Open;Needle | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12259 | Biopsy and autopsy inflammation type | BpApInflamTyp | Perivascular inflammation is focused around blood vessels, whereas diffuse inflammation also spreads across the muscle tissue. Inflammatory cells identified include lymphocytes, neutrophils, macrophages, and eosinophils. At times, microorganisms can be identified and should be mentioned | Perivascular inflammation is focused around blood vessels, whereas diffuse inflammation also spreads across the muscle tissue. Inflammatory cells identified include lymphocytes, neutrophils, macrophages, and eosinophils. At times, microorganisms can be identified and should be mentione | Specify | Perivascular;Diffuse;Associated with myofiber damage;Inflammatory cells identified;Microorganisms identified | Perivascular;Diffuse;Associated with myofiber damage;Inflammatory cells identified;Microorganisms identified | Alphanumeric |
Only answered if "Inflammation" is answered for "Which of the following diagnostic abnormalities were noted on histochemical stains?" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17899 | Preservation technique not used indicator | PreservTechNotUseInd | Indicates preservation technique used is not known | Indicates preservation technique used is not known | Freezing or Fixation Used? | Yes;No:Unknown | Yes;No:Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12270 | Biopsy and autopsy antibodies used name | BpApAntibodUseName | List the names of antibodies used | List the names of antibodies used | Name of antibodies used | Alphanumeric |
If names of antibodies used is not known, select Not known. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12233 | Preservation technique used type | PresrvtnTechnqUseTyp | Type of preservation technique used to preserve the specimen | Type of preservation technique used to preserve the specimen | Freezing or Fixation Used? | Frozen;Formalin-fixed;Paraffin-embedded;Epon-embedded | Frozen;Formalin-fixed;Paraffin-embedded;Epon-embedded | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12521 | Specimen type 2 fiber muscle biopsy percent result number | SpecTyp2FibMuscBiopPctResltNum | Result for type 2 fiber muscle biopsy percent | Result for type 2 fiber muscle biopsy percent | Numeric Values |
Only record Type 2 fiber percentage if Type 2 predominance is completed |
No references available | Adult | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12248 | Pathologist name | PathologistName | Name of pathologist who diagnosed the case | Name of pathologist who diagnosed the case | Name of pathologist who diagnosed the case | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12260 | Biopsy and autopsy perivascular inflammation type | BpApPerivasInflamTyp | Evidence of vascular damage includes damaged vessels in association with perivascular inflammation and the presence of fibrin thrombi located within vascular spaces | Evidence of vascular damage includes damaged vessels in association with perivascular inflammation and the presence of fibrin thrombi located within vascular space | Perivascular, Specify | Evidence of vascular damage;Thrombi identified in blood vessels | Evidence of vascular damage;Thrombi identified in blood vessels | Alphanumeric |
Only answered if "Perivascular" is answered for "Inflammation" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17900 | Age presentation year value | AgePresentYearVal | Age (in years) of participant/subject at presentation | Age (in years) of participant/subject at presentation | Age at presentation | Numeric Values | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
