CDE Detailed Report
Disease: content
Subdomain Name: Laboratory Tests and Biospecimens%2FBiomarkers
CRF: welcome
Displaying 51 - 68 of 68
Subdomain Name: Laboratory Tests and Biospecimens%2FBiomarkers
CRF: welcome
Displaying 51 - 68 of 68
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C12240 | Biochemical or genetic test performed indicator | BiochemGenTestPerfInd | Indicator of whether subsequent biochemical or genetic testing was performed | Indicator of whether subsequent biochemical or genetic testing was performed | Was subsequent biochemical or genetic testing performed? | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12275 | Biopsy and autopsy absent immunoreactivity assay name | BpApAbsntImnreacAssyName | Absent immunoreactivity | Absent immunoreactivity | Assays with absent immunoreactivity | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12254 | Biopsy and autopsy myopathy-associated pathological structures type | BpApMyopAsscPathoStrucTyp | The type of myopathy-associated pathological structures seen in the histology of the biopsy or autopsy specimen | The type of myopathy-associated pathological structures seen in the histology of the biopsy or autopsy specimen | Myopathy-associated pathological structures, specify | Central nuclei;Eccentric nuclei;Inclusion bodies/Rimmed vacuoles;Nemaline rods;Ragged red fibers;COX-negative fibers;Central cores;Minicores;Marked hypertrophy of type 1 fibers | Central nuclei;Eccentric nuclei;Inclusion bodies/Rimmed vacuoles;Nemaline rods;Ragged red fibers;COX-negative fibers;Central cores;Minicores;Marked hypertrophy of type 1 fibers | Alphanumeric |
Only answered if "Myopathy-associated pathological structures" is answered for "Which of the following diagnostic abnormalities were noted on histochemical stains?" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12528 | Biopsy and autopsy nemaline rods restricted to one fiber text | BpApNemaRodRstrct1FibTxt | Nemaline rods restricted to one fiber text | Nemaline rods restricted to one fiber text | Restricted to one fiber type, specify which | Numeric Values |
Only answered if "Nemaline rod , restricted to one fiber type" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental-Highly Recommended | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12228 | Tissue specimen name | TissSpecmnName | Tissue specimen name collected from the participant | Tissue specimen name collected from the participant | Tissue collected | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.10 | 2024-02-29 15:54:16.0 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12265 | Biopsy and autopsy diagnostic abnormalities severity grade | BpApDiagnosAbnrmlSeverGrade | Severity of the diagnostic muscle abnormalities | Severity of the diagnostic muscle abnormalities | Mild/Moderate/Severe | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
Only answered if Fatty replacement; Endomysial fibrosis; or Myofiber degeneration is answered for "diagnostic abnormalities" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17905 | Biopsy and autopsy abnormal storage material text | BpApAbnrmlStrgMatTxt | Text describing biopsy or autopsy material that has been stored abnormally | Text describing biopsy or autopsy material that has been stored abnormall | Describe any abnormal storage material identified | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12241 | Biochemical or genetic test name | BiochemGenTestName | Name of the biochemical or genetic test as performed on the specimen | Name of the biochemical or genetic test as performed on the specimen | Test Name | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12276 | Biopsy and autopsy mitochondria abnormality type | BpApMitochAbnrmlyTyp | Type of mitochondria abnormality in muscle biopsy | Type of mitochondria abnormality in muscle biopsy | Abnormalities noted in Mitochondria, specify | Abnormal shape;Abnormal location;Abnormal numbers;Abnormal architecture | Abnormal shape;Abnormal location, specify;Abnormal numbers;Abnormal architecture | Alphanumeric |
Choose all that apply. Only answered if "Mitochondria" is answered for "Abnormalities noted in" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C12255 | Biopsy and autopsy central nuclei estimated fibers percent value | BpApCentrlNucEstFibPrsVal | Estimated percent of fibers in central nuclei | Estimated percent of fibers in central nucle | Specify estimated percent of fibers (include eccentric nuclei) | Numeric Values |
Only answered if "Central nuclei" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12529 | Biopsy and autopsy ragged red fibers estimated count | BpApRggdRdFibEstCt | Ragged red fibers estimated number | Ragged red fibers estimated number | Ragged red fibers, Estimated number | Numeric Values |
Only answered if "Ragged red fibers" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12229 | Tissue specimen size measurement | TissSpecmnSizeMeasr | Measurement of the size of the tissue specimen collected | Measurement of the size of the tissue specimen collected | Size of tissue collected | Numeric Values |
This information may not be available for autopsy tissue. |
No references available | Adult;Pediatric | Supplemental-Highly Recommended | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
centimeter | |||||||||
| C12266 | Biopsy and autopsy excessive intracellular lipid severity grade | BpApExesIntracellLipSeverGrade | Severe lipid storage pathology involves excess Oil Red O+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild lipid storage pathology is difficult to determine at the light microscopic level and may only be evident on Oil Red O stain or on electron microscopy | Severe lipid storage pathology involves excess Oil Red O+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild lipid storage pathology is difficult to determine at the light microscopic level and may only be evident on Oil Red O stain or on electron microscop | Specify severity | Mild;Severe | Mild;Severe | Alphanumeric |
Only answered if "Excessive intracellular lipid" is answered for "Abnormal storage material" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18828 | Histochemical stains used other text | HistchmclStainUseOTH | The free-text field related to 'Histochemical stains used type' specifying other text. Type of standard histochemical stains used on the tissue specimen | The free-text field related to 'Histochemical stains used type' specifying other text. Type of standard histochemical stains used on the tissue specimen | Other, specify | Alphanumeric |
Choose all that apply |
No references available | Adult;Pediatric | Supplemental-Highly Recommended | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C12242 | Biochemical or genetic test result value | BiochemGenTestResltVal | Results of the biochemical or genetic test performed on the specimen | Results of the biochemical or genetic test performed on the specimen | Results (including units) | Alphanumeric |
Only answered if "Yes" is answered for "Was subsequent biochemical or genetic testing performed?" Include units with results, if applicable. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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| C12517 | Fatty replacement severity status | FttyReplcmntSeverStat | Severity of the Fatty replacement muscle diagnostic abnormalities | Severity of the fatty replacement muscle diagnostic abnormalities | Fatty replacement | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
No instructions available |
No references available | Adult | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C12256 | Biopsy and autopsy eccentric nuclei estimated fibers percent value | BpApEccNucEstFibPrcntVal | Estimated percent of fibers in eccentric nuclei | Estimated percent of fibers in eccentric nucle | Specify estimated percent of fibers (if not quantified above) | Numeric Values |
Only answered if "Eccentric nuclei" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations |
Free-Form Entry |
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| C12530 | Biopsy autopsy COX-negative fibers estimated count | BpApCOXNegFibEstCt | COX-negative fibers estimated number | COX-negative fibers estimated number | COX-negative fibers, Estimated number | Alphanumeric |
Only answered if "COX-negative fibers" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsy and Autopsy Tissue | Laboratory Tests and Biospecimens%2FBiomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
