CDE Detailed Report

Disease: system
Subdomain Name: Laboratory Tests and Biospecimens/Biomarkers
CRF: content

Displaying 151 - 166 of 166
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C19953 Immunohistochemistry dystrophin C terminus status IHCDysCTerminStat The status of dystrophin C terminus (DYS2) in immunohistochemistry The status of dystrophin C terminus (DYS2) in immunohistochemistry Dystrophin C terminus (DYS2) Absent;Reduced;Cytoplasmic;Normal Absent;Reduced;Cytoplasmic;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C20326 Biopsy autopsy excessive glycogen status BpApExessGlycoStat The status related to glycogen storage pathology which involves excess PAS+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild glycogen storage pathology is difficult to determine at the light microscopic level and may only be evident on PAS stain or electron microscopy The status related to glycogen storage pathology which involves excess PAS+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild glycogen storage pathology is difficult to determine at the light microscopic level and may only be evident on PAS stain or electron microscop Excessive glycogen Absent;Mild;Marked Absent;Mild;Marked Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-18 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19889 Symptom presentation weakness distribution type SymptmPresentWeakDisTyp Weakness distribution symptoms participant/ subject shows at presentation Weakness distribution symptoms participant/ subject shows at presentation Weakness (distribution) Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify Alphanumeric

Check all that apply.

 No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19985 Immunohistochemistry CD45 presence status IHCCD45PresStat The status of the presence of CD45 in immunohistochemistry The status of the presence of CD45 in immunohistochemistry CD45 Absent;Present Absent;Present Alphanumeric

If present; specify the percent of lymphocytes

 Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19921 Biopsy and autopsy central cores estimated percentage value BpApCentralCoreEstCt Central cores estimated percentage value Central cores estimated percentage value Moderate (present in:) Numeric Values No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Free-Form Entry

 0 100 percent
C19932 Biopsy and autopsy ring fibers status BpApRingFibStat Ring fibers status in biopsy/autopsy Ring fibers status in biopsy/autopsy Ring fibers Absent;Sparse;Moderate Absent;Sparse;Moderate Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C12276 Biopsy and autopsy mitochondria abnormality type BpApMitochAbnrmlyTyp Type of mitochondria abnormality in muscle biopsy Type of mitochondria abnormality in muscle biopsy Abnormalities noted in Mitochondria, specify Abnormal shape;Abnormal location;Abnormal numbers;Abnormal architecture;Abnormal size Abnormal shape;Abnormal location, specify;Abnormal numbers;Abnormal architecture;Abnormal size Alphanumeric

Choose all that apply. Only answered if "Mitochondria" is answered for "Abnormalities noted in"

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Multiple Pre-Defined Values Selected
C19964 Immunohistochemistry alpha sarcoglycan status IHCAlpSarcoglyStat The status of Alpha sarcoglycan in immunohistochemistry The status of Alpha sarcoglycan in immunohistochemistry Alpha sarcoglycan Absent;Reduced;Normal Absent;Reduced;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19900 Laboratory findings autoantibody known text LabFinAutoAntiKnownText Text of the known autoantibodies in patient Text of the known autoantibodies in patient Known autoantibodies in patient Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 4000

Free-Form Entry
C19996 Biopsy and autopsy additional immunohistochemical assays performed text BpApAddImmhistchmAssPerText Specify any additional immunohistochemical/immunoflourescence assays performed Specify any additional immunohistochemical/immunoflourescence assays performed Additional immunohistochemical/immunoflourescence assays performed Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 4000

Free-Form Entry
C00035 Gender type GenderTyp Self-reported gender of the participant/subject Self-reported gender of the participant/subjec Gender of Patient Alphanumeric

Choose one. Response is obtained by report of the participant/subject or caretaker.

 The NIH Guidelines on Inclusion of Women and Minorities as Subjects in Clinical Research: The Office of Management and Budget Directive No. 15 (http://grants.nih.gov/grants/funding/women_min/guidelines_update.htm) Adult;Pediatric Core 3.00 2013-08-28 16:08:00.453 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected

 2200604
C12238 Biopsy and autopsy epon embedded tissue abnormalities location type BpApEponEmbedTissAbnrmlLocTyp Type of abnormality observed microscopically in epon-embedded tissue specimen Type of abnormality observed microscopically in epon-embedded tissue specimen Abnormalities noted in Nuclei;Contractile apparatus;Sarcotubular organization;Mitochondria, specify;Basal lamina;Satellite cells;Intramuscular nerve twigs Nuclei;Contractile apparatus;Sarcotubular organization;Mitochondria, specify (choose all that apply);Basal lamina;Satellite cells;Intramuscular nerve twigs Alphanumeric

No instructions available

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Multiple Pre-Defined Values Selected
C19943 Biopsy and autopsy intramuscular nerve branche status BpApIntramusNervBranchStat The status of the presence of intramuscular nerve branches The status of the presence of intramuscular nerve branches Intramuscular nerve branches Absent;Present Absent;Present Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C12529 Biopsy and autopsy ragged red fibers estimated count BpApRggdRdFibEstCt Ragged red fibers estimated number Ragged red fibers estimated number Moderate (present in:) Numeric Values

Only answered if "Ragged red fibers" is answered for "Myopathy-associated pathological structures"

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Free-Form Entry
C19975 Immunohistochemistry CD3 presence status IHCCD3PresStat The status of the presence of CD3 in immunohistochemistry The status of the presence of CD3 in immunohistochemistry CD3 Absent;Present Absent;Present Alphanumeric

If present; specify the percent of lymphocytes

 Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19911 Biopsy and autopsy trichome red inclusions estimated percentage count BpApRedInclusTrichEstCt Red inclusions on trichome estimated percentage value Red inclusions on trichome estimated percentage value Moderate (present in:) Numeric Values No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Free-Form Entry
CSV