CDE Detailed Report

Disease: Mitochondrial Disease
Sub-Domain: Cognitive
CRF: Brief Test of Adult Cognition by Telephone (BTACT)

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CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C21858 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task experimental score BTACTStopAndGoExptalScore Total number correct in experimental condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct in experimental condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct in Stop and Go (experimental condition) Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:01:18.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 20
C21895 Brief Test of Adult Cognition by Telephone (BTACT) - Thirty Seconds and Counting Task (30-SACT) total score BTACTThirtySecondsTotalScore Total number of digits produced score, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Total number of digits produced score, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Total Score in Thirty Seconds and Counting task Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 12:05:39.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 200
C21860 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task normal baseline score BTACTStopAndGoNormBseScore Total number correct in normal baseline condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct in normal baseline condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct in Stop and Go (at baseline) Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:08:49.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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1
C21896 Brief Test of Adult Cognition by Telephone (BTACT) - Time duration BTACTTimeDur Time duration in seconds, as part of Brief Test of Adult Cognition by Telephone (BTACT) Time duration in seconds, as part of Brief Test of Adult Cognition by Telephone (BTACT) Duration of test (in seconds) 1-15;16-30;31- 1-15;16-30;31- Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 12:07:43.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C21862 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task other trial score BTACTStopAndGoNoSwtchTrlScore Total number of other experimental trials correct, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number of other experimental trials correct, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number of other experimental trials correct score Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:18:16.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 6
C21897 Brief Test of Adult Cognition by Telephone (BTACT) - Total intrusion count BTACTTotalIntrusionNumber Total Number of intrusions, as a part of Brief Test of Adult Cognition by Telephone (BTACT) Total Number of intrusions, as a part of Brief Test of Adult Cognition by Telephone (BTACT) Number of intrusions Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 12:13:08.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 100
C21863 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task question type BTACTStopAndGoQstnTyp Type of questions asked in the Stop And Go Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Type of questions asked in the Stop And Go Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Type of Question in Stop and Go task Green;Red Green;Red Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:23:50.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C21898 Brief Test of Adult Cognition by Telephone (BTACT) - Total repitition count BTACTTotalRepetitionNumber Total Number of repetitions, as a part of Brief Test of Adult Cognition by Telephone (BTACT) Total Number of repetitions, as a part of Brief Test of Adult Cognition by Telephone (BTACT) Number of repetitions Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 12:15:41.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 100
C21865 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task response type BTACTStopAndGoRspnsTyp Type of responses in the Stop And Go Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Type of responses in the Stop And Go Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Type of Response in Stop and Go task Stop;Go Stop;Go Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:28:17.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C21840 Brief Test of Adult Cognition by Telephone (BTACT) - Category fluency test category BTACTCategoryFluencyCat Category of responses in the Category Fluency Test, as part of Brief Test of Adult Cognition by Telephone (BTACT). Category of responses in the Category Fluency Test, as part of Brief Test of Adult Cognition by Telephone (BTACT). Repeat as many of the following numbers. Are these audible? Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 08:22:02.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points 255

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C21867 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task reverse baseline score BTACTStopAndGoRvrsBseScore Total number correct in reverse baseline condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct in reverse baseline condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Score recorded in reverse baseline condition in Stop and Go task Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:35:14.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 20
C21845 Brief Test of Adult Cognition by Telephone (BTACT) - Category fluency test correct response count BTACTCatFluencyCorrectRespNum Number of correct responses in the Category Fluency Test, as part of Brief Test of Adult Cognition by Telephone (BTACT). Number of correct responses in the Category Fluency Test, as part of Brief Test of Adult Cognition by Telephone (BTACT). Number of correct responses Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 08:40:55.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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C21878 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task switch trial score BTACTStopAndGoSwtchTrlScore Total number of trials correct after switch in experimental condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number of trials correct after switch in experimental condition, as part of Brief Test of Adult Cognition by Telephone(BTACT). Total number correct after switch in condition Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 10:42:09.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 32
C21846 Brief Test of Adult Cognition by Telephone (BTACT) - Mean latency time lapse millisecond measurement BTACTMeanLatencyTimeDur Mean latency measurement of time lapsed in milliseconds, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Mean latency measurement of time lapsed in milliseconds, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Mean latency time lapse millisecond recording Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 08:49:17.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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C21881 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task test type BTACTStopAndGoTestTyp Type of experimental task, as part of Brief Test of Adult Cognition by Telephone(BTACT). Type of experimental task, as part of Brief Test of Adult Cognition by Telephone(BTACT). Stop and Go experimental task type Baseline Normal;Baseline Switched;Experimental Baseline Normal;Baseline Switched;Experimental Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 11:02:03.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C21849 Brief Test of Adult Cognition by Telephone (BTACT) - Median latency time lapse millisecond measurement BTACTMedianLatencyTimeDur Median latency measurement of time lapsed in milliseconds, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Median latency measurement of time lapsed in milliseconds, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Median latency time lapse millisecond recording Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 09:14:52.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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C21891 Brief Test of Adult Cognition by Telephone (BTACT) - Stop and go task experimental task type BTACTStopAndGoTotExptalTestTyp Type of test, as part of Brief Test of Adult Cognition by Telephone(BTACT). Type of test, as part of Brief Test of Adult Cognition by Telephone(BTACT). Test type Normal;Reverse Normal;Reverse Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 11:15:58.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C21854 Brief Test of Adult Cognition by Telephone (BTACT) - Number series response type text BTACTNumberSeriesItemTxt Text for type of responses in the Number Series Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Text for type of responses in the Number Series Task, as part of Brief Test of Adult Cognition by Telephone (BTACT). Type of response Alphanumeric Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 09:22:21.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points 50

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C21893 Brief Test of Adult Cognition by Telephone (BTACT) - Thirty Seconds and Counting Task (30-SACT) error count BTACTThirtySecondsErrorNum Number of errors in the Thirty Seconds and Counting Task (30-SACT), as part of Brief Test of Adult Cognition by Telephone (BTACT). Number of errors in the Thirty Seconds and Counting Task (30-SACT), as part of Brief Test of Adult Cognition by Telephone (BTACT). Total error count in Thirty Seconds and Counting task Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 11:58:54.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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C21856 Brief Test of Adult Cognition by Telephone (BTACT) - Series complete total number score BTACTNumSeriesCorctRespnsScore Score of total number of items/series completed correctly in the Number Series Task, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Score of total number of items/series completed correctly in the Number Series Task, as a part of the Brief Test Adult Cognition by Telephone (BTACT) Series total number score Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 09:57:01.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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0 5
C21894 Brief Test of Adult Cognition by Telephone (BTACT) - Thirty Seconds and Counting Task (30-SACT) last number reached text BTACTThirtySecondsLastNumTxt Text for last number reached in the Thirty Seconds and Counting Task (30-SACT), as part of Brief Test of Adult Cognition by Telephone (BTACT). Text for last number reached in the Thirty Seconds and Counting Task (30-SACT), as part of Brief Test of Adult Cognition by Telephone (BTACT). Last number reached in Thirty Seconds and Counting task Numeric Values Tun, P. A., & Lachman, M. E. (2006). Telephone assessment of cognitive function in adulthood: The Brief Test of Adult Cognition by Telephone (BTACT). Age and Ageing, 629-632. doi:10.1093/ageing/afl094 Adult Supplemental 1.00 2016-06-06 12:02:19.0 Brief Test of Adult Cognition by Telephone (BTACT) Cognitive Outcomes and End Points

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