CDE Detailed Report
Disease: Multiple Sclerosis
Sub-Domain: Neuropsychological Testing
CRF: Expanded Disability Status Scale (EDSS)
Displaying 1 - 1 of 1
Sub-Domain: Neuropsychological Testing
CRF: Expanded Disability Status Scale (EDSS)
Displaying 1 - 1 of 1
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Additional Notes (Question Text) | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guideline) | Sub Domain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C14713 | Expanded Disability Status Scale (EDSS) - function scale | EDSSFunctionScl | Using the Expanded Disability Status Scale (EDSS) by Kurtzke, the current disability from disease experienced in terms of level of function of the participant/subject | Using the Expanded Disability Status Scale (EDSS) by Kurtzke, the current disability from disease experienced in terms of level of function of the participant/subject | Expanded Disability Status Scale (EDSS) | 0.0;1.0;1.5;2.0;2.5;3.0;3.5;4.0;4.5;5.0;5.5;6.0;6.5;7.0;7.5;8.0;8.5;9.0;9.5;10.0 | Normal neurological exam (all grade 0 in all Functional System (FS) scores*);No disability, minimal signs in one FS* (i.e., grade 1);No disability, minimal signs in more than one FS* (more than 1 FS grade 1);Minimal disability in one FS (one FS grade 2, others 0 or 1);Minimal disability in two FS (two FS grade 2, others 0 or 1);Moderate disability in one FS (one FS grade 3, others 0 or 1) or mild disability in three or four FS (three or four FS grade 2, others 0 or 1) though fully ambulatory;Fully ambulatory but with moderate disability in one FS (one grade 3) and one or two FS grade 2;Fully ambulatory without aid, self-sufficient, up and about some 12 hours a day despite relatively severe disability consisting of one FS grade 4 (others 0 or 1), or combination of lesser grades exceeding limits of previous steps, able to walk without aid or rest some 500 meters;Fully ambulatory without aid, up and about much of the day, able to work a full day, may otherwise have some limitation of full activity or require minimal assistance, characterized by relatively severe disability usually consisting of one FS grade 4 (others or 1) or combinations of lesser grades exceeding limits of previous steps, able to walk without aid or rest some 300 meters;Ambulatory without aid or rest for about 200 meters, disability severe enough to impair full daily activities (e.g., to work a full day without special provisions), (Usual FS equivalents are one grade 5 alone, others 0 or 1, or combinations of lesser grades usually exceeding specifications for step 4.0);Ambulatory without aid for about 100 meters, disability severe enough to preclude full daily activities, (Usual FS equivalents are one grade 5 alone, others 0 or 1, or combination of lesser grades usually exceeding those for step 4.0);Intermittent or unilateral constant assistance (cane, crutch, brace) required to walk about 100 meters with or without resting, (Usual FS equivalents are combinations with more than two FS grade 3+);Constant bilateral assistance (canes, crutches, braces) required to walk about 20 meters without resting, (Usual FS equivalents are combinations with more than two FS grade 3+);Unable to walk beyond approximately 5 meters even with aid, essentially restricted to wheelchair, wheels self in standard wheelchair and transfers alone, up and about in wheelchair some 12 hours a day, (Usual FS equivalents are combinations with more than one FS grade 4+, very rarely pyramidal grade 5 alone);Unable to take more than a few steps, restricted to wheelchair, may need aid in transfer, wheels self but cannot carry on in standard wheelchair a full day, May require motorized wheelchair, (Usual FS equivalents are combinations with more than one FS grade 4+);Essentially restricted to bed or chair or perambulated in wheelchair, but may be out of bed itself much of the day, retains many self-care functions, generally has effective use of arms, (Usual FS equivalents are combinations, generally grade 4+ in several systems);Essentially restricted to bed much of day, has some effective use of arm(s), retains some self-care functions, (Usual FS equivalents are combinations, generally 4+ in several systems);Helpless bed patient, can communicate and eat, (Usual FS equivalents are combinations, mostly grade 4+);Totally helpless bed patient, unable to communicate effectively or eat/swallow, (Usual FS equivalents are combinations, almost all grade 4+);Death due to MS | Numeric Values |
The EDSS is highly recommended to categorize severity of neurological disability in multiple sclerosis. |
Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded Disability status scale (EDSS). Neurology. 1983 Nov;33(11):1444-52. Haber A, LaRocca NG. eds. Minimal Record of Disability for multiple sclerosis. New York: National Multiple Sclerosis Society; 1985. | Adult;Pediatric | Supplemental | 3.00 | 2013-06-11 00:00:00.0 | Expanded Disability Status Scale (EDSS) | Neuropsychological Testing | Outcomes and End Points |
Single Pre-Defined Value Selected |
