CDE Detailed Report
Disease: system
Subdomain Name: Other Clinical Data
CRF: files
Displaying 151 - 175 of 175
Subdomain Name: Other Clinical Data
CRF: files
Displaying 151 - 175 of 175
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C15084 | Brain atrophy Braak and Braak neurofibrillary stage indicator | BrAtBraakBraakNeurofibStageInd | Indicator of whether neuronal tangles are present | Indicator of whether neuronal tangles are present | Braak & Braak Neurofibrillary Tangle Stage | Absent;Present;Not assessed;Not available | Absent;Present;Not assessed;Not available | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14992 | Brain atrophy striatum status cribrosus or lacunaris severity result | BrAtStrStatusCribLacunSevReslt | Quantitative result of the severity of atrophy located in the status cribrosus or lacunaris, or both | Quantitative result of the severity of atrophy located in the status cribrosus or lacunaris, or bot | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C02411 | Laterality type | LatTyp | Laterality type relative to the anatomic site of the body examined or affected | Laterality type relative to the anatomic site of the body examined or affected | Bilateral;Left;Right;Unknown | Bilateral;Left;Right;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-08-28 16:08:00.453 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18994 | Microscopical examination blocks other text | MicroExamBlocksOTH | The free-text field related to 'Microscopical examination blocks source' specifying other text. The source of blockage based on microscopical examination of brain | The free-text field related to 'Microscopical examination blocks source' specifying other text. The source of blockage based on microscopical examination of brain | Other, specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15063 | Brain atrophy nucleus coeruleus globosum neuronal tangles status | BrAtNucCoerGloNeurTanglesStat | Status of globosum neuronal tangles (GNT) in the nucleus coeruleus | Status of globosum neuronal tangles (GNT) in the nucleus coeruleu | Globosum neuronal tangles (GNT) | Absent;Present | Absent;Present | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14971 | Macroscopical examination fresh brain source | MacroExamFreshBrainSource | The part(s) of the fresh brain used for macroscopical examination | The part(s) of the fresh brain used for macroscopical examination | Macroscopical examination Fresh | Whole brain;Left half brain;Right half brain;Not available;Other specify | Whole brain;Left half brain;Right half brain;Not available;Other specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15095 | Hemorrhages single or multiple event category | HemorrhageSingMultiEvntCat | Category of the hemorrhages | Category of the hemorrhages | Yes | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15031 | Brain atrophy hippocampal formation neuronal loss indicator | BrAtHippocampFormNeurLossInd | Indicator of neuronal loss in the hippocampal formation | Indicator of neuronal loss in the hippocampal formatio | Hippocampal formation Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15042 | Brain atrophy fibrillary astrocytosis severity result | BrAtFibAstroSevReslt | Quantitative result of the severity of fibrillary astrocytosis in each location of the caudate nucleus | Quantitative result of the severity of fibrillary astrocytosis in each location of the caudate nucleus | Yes, neuronal loss | 0;1+/4+;2+/4+;3+/4+;4+/4+;NA | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available | Alphanumeric |
Answer for caudate nucleus, pontes griseum or gray matter caudo-lenticular bridges, putamen, and globus pallidus anatomic sites. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08156 | Specimen other postmortem indicator | SpecmnOtherPstmortemInd | Indicator whether other banked postmortem specimens (e.g., blood, spinal cord, nerve, muscle) exist | Indicator whether other banked postmortem specimens (e.g., blood, spinal cord, nerve, muscle) exist | Are other banked postmortem specimens available? (e.g. blood, spinal cord, nerve, muscle) | Yes;No | Yes;No | Alphanumeric |
If YES is answered then explain what other type(s) of postmortem samples exist |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15074 | Brain atrophy cerebellum cortical neuronal loss in associative layer severity result | BrAtCerCortNeurLosAsocSevReslt | Quantitative result of the severity of cortical neuronal loss in the associative layer of the cerebellum | Quantitative result of the severity of cortical neuronal loss in the associative layer of the cerebellum | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14982 | Brain atrophy coronal sections hippocampal formation severity result | BrAtCorSecHippFormSevReslt | Quantitative result of the severity of hippocampal formation atrophy in the coronal sections of the brain | Quantitative result of the severity of hippocampal formation atrophy in the coronal sections of the brain | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15106 | Clinicopathology diagnosis final type | ClinicopathDiagnosFinalTyp | The participant/subject's final clinicopathological diagnosis | The participant/subject's final clinicopathological diagnosis | Yes | Huntington's disease;Encephalopathy of hypoxic-ischemic type, acute;Alzheimer changes;Status cribrosus and lucanaris;There is no diagnostic abnormality recognized;Other, specify | Huntington's disease;Encephalopathy of hypoxic-ischemic type, acute;Alzheimer changes;Status cribrosus and lucanaris;There is no diagnostic abnormality recognized;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17755 | Striatum atrophy claustrum atrophy status | StrAtrophyClaustrumAtrophyStat | Status of atrophy in the claustrum | Status of atrophy in the claustru | Claustrum atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17764 | Striatum atrophy red nucleus atrophy severity result | StrAtrophyRedNuAtrophySevReslt | Quantitative result of the severity of atrophy located in the red nucleus | Quantitative result of the severity of atrophy located in the red nucleu | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15053 | Brain atrophy substantia nigra pars compacta neuronal loss indicator | BrAtSubNigraParsCompNeurLosInd | Indicator of neuronal loss in the pars compacta of the substantia nigra | Indicator of neuronal loss in the pars compacta of the substantia nigr | Pars compacta Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08171 | Diffuse plaques density category | DiffusePlaqDenstyCat | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Immatue and diffuse type plaques (are plaques without the dense core of the neuritic plaques and are either with [immature] or without [diffuse] dystrophic neurites) | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | Alphanumeric |
Amyloid plaques |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15085 | Silver staining methods type | SilverStainMethdsTyp | Silver staining methods used for identifying Alzheimer disease type changes | Silver staining methods used for identifying Alzheimer disease type changes | Silver methods | Bielschowsky;Other, specify;Not assessed;Missing/Unknown | Bielschowsky;Other, specify;Not assessed;Missing/Unknown | Alphanumeric |
Answer for each type of microscopic brain abnormality |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15021 | Brain atrophy substantia nigra appearance grade | BrAtSubstantiaNigraAppGrade | Grade of pigmentation of the substantia nigra | Grade of pigmentation of the substantia nigra | Substantia nigra | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15032 | Brain atrophy hippocampal formation neuronal loss severity result | BrAtHippocFormNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the hippocampal formation | Quantitative result of the severity of neuronal loss in the hippocampal formation | Yes, neuronal loss | 1+/4+;2+/4+;3+/4+;4+/4+ | 1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if 'Yes, neuronal loss' is answered for 'Hippocampal formation neuronal loss' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C04802 | Death date and time | DeathDateTime | Date (and time, if known) of participant's/subject's death | Date (and time, if known) of participant's/subject's death | Date of Death; Time of Death | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
ISO 8601 - http://www.iso.org/iso/iso_catalogue.htm | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
2004152 | |||||||||
| C18995 | Brain atrophy thalamus neuronal loss nuclei other text | BrAtThalamusNeurLossNucOTH | The free-text field related to 'Brain atrophy thalamus neuronal loss nuclei name' specifying other text. Name of the nuclei in the thalamus involved in the neuronal loss | The free-text field related to 'Brain atrophy thalamus neuronal loss nuclei name' specifying other text. Name of the nuclei in the thalamus involved in the neuronal loss | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15064 | Brain atrophy nucleus coeruleus globosum neuronal tangles (GNT) severity result | BrAtNucCoerGloNeurTanSevReslt | Quantitative result of the severity of GNT in the nucleus coeruleus | Quantitative result of the severity of GNT in the nucleus coeruleu | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14972 | Macroscopical examination fixed brain source | MacroExamFixedBrainSource | The part(s) of the fixed brain used for macroscopical examination | The part(s) of the fixed brain used for macroscopical examination | Macroscopical examination Fixed | Whole brain;Left half brain;Right half brain;Not available;Other, specify | Whole brain;Left half brain;Right half brain;Not available;Other, specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15096 | Hemorrhages single or multiple vascular territories name | HemSingMultiVascTerrName | Name of the vascular territories where hemorrhages occur | Name of the vascular territories where hemorrhages occur | Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) | ACA;MCA;PCA;Combined | ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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