CDE Detailed Report

Disease: system
Subdomain Name: Other Clinical Data
CRF: files

Displaying 151 - 175 of 175
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C15038 Brain atrophy neuronal loss nucleus accumbens severity result BrAtNeurLossNucAccSevReslt Quantitative result of the severity of neuronal loss in the nucleus accumbens Quantitative result of the severity of neuronal loss in the nucleus accumbens Nucleus accumbens 0;1+/4+;2+/4+;3+/4+;4+/4+;NA 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available Alphanumeric

No additional instructions

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Single Pre-Defined Value Selected

C08152 Brain tissue frozen indicator BrainTissFrozenInd Indicator of whether banked frozen brain tissue is accessible Indicator of whether banked frozen brain tissue is accessible Is banked frozen brain tissue available? Yes;No Yes;No Alphanumeric

No additional instructions

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C15070 Brain atrophy medulla oblongata dorsal nucleus of vagus reticular formation severity result BrAtMedObDorNucVagRetFSevReslt Quantitative result of the severity of dorsal nucleus of vagus reticular formation: LBCN and LN in the medulla oblongata Quantitative result of the severity of dorsal nucleus of vagus reticular formation: LBCN and LN in the medulla oblongata Present Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Medulla oblongata

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C14978 Brain atrophy coronal sections cerebral cortex severity result BrainAtCorSecCereCorSevReslt Quantitative result of the severity of cerebral cortex atrophy in the coronal sections of the brain Quantitative result of the severity of cerebral cortex atrophy in the coronal sections of the brain Present 0;1+/4+;2+/4+;3+/4+;4+/4+ 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe Alphanumeric

Coronal slices: On gross examination of the coronal sections

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C14989 Brain atrophy striatum globus pallidus external segment severity result BrAtStrGlPaExternlSevReslt Quantitative result of the severity of atrophy located in the globus pallidus, external segment Quantitative result of the severity of atrophy located in the globus pallidus, external segmen External segment atrophy Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Alphanumeric

Striatum atrophy; Globus pallidus

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C17400 Other pathology ischemic vascular disease text OthrPathlgyIschmcVasclrDisTxt Text field to describe the presence of another ischemic or vascular disease not specifically mentioned previously Text field to describe the presence of another ischemic or vascular disease not specifically mentioned previously Yes, specify Alphanumeric No references available Adult;Pediatric Supplemental 1.00 2012-12-20 00:00:00.0 Neuropathology Data Form Other Clinical Data Assessments and Examinations 255

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C15049 Brain atrophy red nucleus neuronal loss indicator BrAtRedNucNeurLossInd Indicator of neuronal loss in the red nucleus Indicator of neuronal loss in the red nucleu Red nucleus Neuronal loss No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

No additional instructions

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C08167 Brain abnormality microscopic type BrainAbnrmlyMicroscpcTyp Type of microscopic brain abnormality identified through staining Type of microscopic brain abnormality identified through staining Staining methods use for Tangles;Plaques;Lewy bodies;TDP-43 Tangles;Plaques;Lewy bodies;TDP-43 Alphanumeric

For each type of microscopic brain abnormality record the staining methods for immunohistochemistry (IHC) and antibodies

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C15081 Brain atrophy cerebellum myelin loss in cerebellar white matter severity result BrAtCerMyeLosCerWMSevReslt Quantitative result of the severity of myelin loss in the cerebellar white matter of the cerebellum Quantitative result of the severity of myelin loss in the cerebellar white matter of the cerebellu Yes, myelin loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Cerebellum; Cerebellar white matter: Myelin loss

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C15028 Brain atrophy cerebral cortex neuronal loss severity result BrAtCereCortexNeurLossSevReslt Quantitative result of the severity of neuronal loss located in the cerebral cortex Quantitative result of the severity of neuronal loss located in the cerebral corte Yes, neuronal loss 0;1+/4+;2+/4+;3+/4+;4+/4+ 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe Alphanumeric

This question is answered for each of the brain anatomic sites.

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C17762 Striatum atrophy subthalamic nucleus atrophy severity result StrAtrophySubNuAtrophySevReslt Quantitative result of the severity of atrophy located in the subthalamic nucleus Quantitative result of the severity of atrophy located in the subthalamic nucle Present Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Striatum atrophy

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C18667 Data source other text DataSourcOTH The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form Other, specify Alphanumeric

No additional instructions

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C15060 Brain atrophy nucleus coeruleus neuronal loss severity result BrAtNucCoerNeurLossSevReslt Quantitative result of the severity of neuronal loss in the nucleus coeruleus Quantitative result of the severity of neuronal loss in the nucleus coeruleus Yes, neuronal loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Nucleus coeruleus

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C08185 Amyloid angiopathy severity scale AmyldAngpthySevScale Whether or not amyloid deposits are present in the walls of the blood vessels of the central nervous system and if so, their severity Whether or not amyloid deposits are present in the walls of the blood vessels of the central nervous system and if so, their severit Yes None;Mild;Moderate;Severe;Not assessed;Unknown None;Mild;Moderate;Severe;Not assessed;Unknown Alphanumeric

This question is answered only if "Yes" is answered for "Is cerebral amyloid angiopathy present?"

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C15092 Lacunes single or multiple event category LacunesSingMultiEvntCat Category of the lacunes Category of the lacunes Yes Single;Multiple Single;Multiple Alphanumeric

No additional instructions

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C15103 Amyloid angiopathy indicator AmyloidAngiopathyInd Indicator of presence of cerebral amyloid angiopathy Indicator of presence of cerebral amyloid angiopathy Is cerebral amyloid angiopathy present? Yes;No;Unknown;Not assessed Yes;No;Unknown;Not assessed Alphanumeric

No additional instructions

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C15039 Brain atrophy fibrillary astrocytosis nucleus accumbens severity result BrAtFibAstroNucAccSevReslt Quantitative result of the severity of firbrillary astrocytosis in the nucleus accumbens Quantitative result of the severity of fibrillary astrocytosis in the nucleus accumbens Nucleus accumbens 0;1+/4+;2+/4+;3+/4+;4+/4+;NA 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available Alphanumeric

No additional instructions

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C08153 Brain tissue formalin-fixed indicator BrainTissFormalinFixedInd Indicator of whether formalin-fixed brain tissue is accessible Indicator of whether formalin-fixed brain tissue is accessible Is formalin-fixed brain tissue available? Yes;No Yes;No Alphanumeric

No additional instructions

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C15071 Brain atrophy medulla oblongata inferior olivary nucleus indicator BrAtMedObInfOlivaryNucInd Indicator of neuronal loss of the inferior olivary nucleus in the medulla oblongata Indicator of neuronal loss of the inferior olivary nucleus in the medulla oblongata Inferior olivary nucleus No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

Medulla oblongata

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C14979 Brain atrophy coronal sections cerebral white matter status BrainAtCorSecCerWMStat Status of cerebral white matter atrophy of the coronal section upon gross examination Status of cerebral white matter atrophy of the coronal section upon gross examinatio Cerebral white matter atrophy Absent;Present Absent;Present Alphanumeric

Coronal slices: On gross examination of the coronal sections

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C14990 Brain atrophy striatum globus pallidus internal segment severity result BrAtStrGlPaIntrnlSevReslt Quantitative result of the severity of atrophy located in the globus pallidus, internal segment. Quantitative result of the severity of atrophy located in the globus pallidus, internal segment. Internal segment atrophy Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Alphanumeric

Striatum atrophy; Globus Pallidus

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C17752 Photographs macroscopic text PhotographsMacroscopicTxt Description of available macroscopic photographs Description of available macroscopic photographs Yes(Describe…) Alphanumeric No references available Adult Supplemental 3.00 2013-08-30 17:06:52.8 Neuropathology Data Form Other Clinical Data Assessments and Examinations 255

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C15050 Brain atrophy red nucleus neuronal loss severity result BrAtRedNucneurLossSevReslt Quantitative result of the severity of neuronal loss in the red nucleus Quantitative result of the severity of neuronal loss in the red nucleus Yes, neuronal loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

This question is answered if "Yes, neuronal loss" is answered for 'Red nucleus: neuronal loss"

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C08168 Immunohistochemistry stain method name ImmunhistchmstryStainMethdName Name of staining method used for immunohistochemistry Name of staining method used for immunohistochemistry Immunochemistry Alphanumeric

Answer for each type of microscopic brain abnormality

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C15082 Brain atrophy cerebellum dentate nucleus neuronal loss indicator BrAtCerebDenNucNeurLosInd Indicator of neuronal loss in the dentate nucleus of the cerebellum Indicator of neuronal loss in the dentate nucleus of the cerebellum Dentate nucleus Neuronal loss No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

Cerebellum; Dentate nucleus: Neuronal loss

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CSV