CDE Detailed Report
Disease: system
Subdomain Name: Other Clinical Data
CRF: files
Displaying 1 - 50 of 175
Subdomain Name: Other Clinical Data
CRF: files
Displaying 1 - 50 of 175
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C08171 | Diffuse plaques density category | DiffusePlaqDenstyCat | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Immatue and diffuse type plaques (are plaques without the dense core of the neuritic plaques and are either with [immature] or without [diffuse] dystrophic neurites) | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | Alphanumeric |
Amyloid plaques |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18153 | Data unknown text | DataUnknwnTxt | The free-text field to Mark an "X" in to record if data are unknown or not available | The free-text field to Mark an "X" in to record if data are unknown or not availabl | CAG repeat HD-IT 15 CAG repeat expansion unknown | Alphanumeric |
If the size of the HD-IT 15 CAG expansion is unknown, record as Not Known in the next data element. |
Adult;Pediatric | Supplemental | 3.00 | 2013-07-17 09:26:36.973 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 20 |
Free-Form Entry |
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| C15085 | Silver staining methods type | SilverStainMethdsTyp | Silver staining methods used for identifying Alzheimer disease type changes | Silver staining methods used for identifying Alzheimer disease type changes | Silver methods | Bielschowsky;Other, specify;Not assessed;Missing/Unknown | Bielschowsky;Other, specify;Not assessed;Missing/Unknown | Alphanumeric |
Answer for each type of microscopic brain abnormality |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15021 | Brain atrophy substantia nigra appearance grade | BrAtSubstantiaNigraAppGrade | Grade of pigmentation of the substantia nigra | Grade of pigmentation of the substantia nigra | Substantia nigra | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17755 | Striatum atrophy claustrum atrophy status | StrAtrophyClaustrumAtrophyStat | Status of atrophy in the claustrum | Status of atrophy in the claustru | Claustrum atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15053 | Brain atrophy substantia nigra pars compacta neuronal loss indicator | BrAtSubNigraParsCompNeurLosInd | Indicator of neuronal loss in the pars compacta of the substantia nigra | Indicator of neuronal loss in the pars compacta of the substantia nigr | Pars compacta Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15064 | Brain atrophy nucleus coeruleus globosum neuronal tangles (GNT) severity result | BrAtNucCoerGloNeurTanSevReslt | Quantitative result of the severity of GNT in the nucleus coeruleus | Quantitative result of the severity of GNT in the nucleus coeruleu | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14972 | Macroscopical examination fixed brain source | MacroExamFixedBrainSource | The part(s) of the fixed brain used for macroscopical examination | The part(s) of the fixed brain used for macroscopical examination | Macroscopical examination Fixed | Whole brain;Left half brain;Right half brain;Not available;Other, specify | Whole brain;Left half brain;Right half brain;Not available;Other, specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15096 | Hemorrhages single or multiple vascular territories name | HemSingMultiVascTerrName | Name of the vascular territories where hemorrhages occur | Name of the vascular territories where hemorrhages occur | Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) | ACA;MCA;PCA;Combined | ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15032 | Brain atrophy hippocampal formation neuronal loss severity result | BrAtHippocFormNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the hippocampal formation | Quantitative result of the severity of neuronal loss in the hippocampal formation | Yes, neuronal loss | 1+/4+;2+/4+;3+/4+;4+/4+ | 1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if 'Yes, neuronal loss' is answered for 'Hippocampal formation neuronal loss' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C04802 | Death date and time | DeathDateTime | Date (and time, if known) of participant's/subject's death | Date (and time, if known) of participant's/subject's death | Date of Death; Time of Death | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
ISO 8601 - http://www.iso.org/iso/iso_catalogue.htm | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
2004152 | |||||||||
| C08157 | Photograph macroscopic indicator | PhotographsMacroscopicInd | Indicator of whether macroscopic photographs were taken | Indicator of whether macroscopic photographs were taken | Are macroscopic photographs available? | Yes;No | Yes;No | Alphanumeric |
If YES is answered explain what macroscopic photographs were taken |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15075 | Brain atrophy cerebellum cortical neuronal loss in receptive layer indicator | BrAtCerebCortNeurLossRecLayInd | Indicator of cortical neuronal loss in the receptive layer (granular) of the cerebellum | Indicator of cortical neuronal loss in the receptive layer (granular) of the cerebellum | Receptive layer (granular) | No, neuronal loss;Yes, neuronal loss | No, neuronal loss;Yes, neuronal loss | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14983 | Brain atrophy coronal sections amygdala status | BrAtCorSecAmygdalaStat | Status of amygdala atrophy of the coronal sections upon gross examination | Status of amygdala atrophy of the coronal sections upon gross examinatio | Amygdala atrophy | Absent;Present | Absent;Present | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15107 | Huntingtons Disease diagnosis grade | HDDiagnosGrade | The grade of severity of HD or amyloid angiopathy severity | The grade of severity of HD or amyloid angiopathy severity | Final Clinicopathological Diagnosis | Grade 1;Grade 2;Grade 3;Grade 4 | Grade 1;Grade 2;Grade 3;Grade 4 | Alphanumeric |
Only answered if "Huntington disease" or "Cerebral amyloid angiopathy" are answered for Final Clinicopathological diagnoses |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15043 | Brain atrophy thalamus neuronal loss indicator | BrAtThalamusNeurLossInd | Indicator of neuronal loss in the thalamus | Indicator of neuronal loss in the thalamu | Thalamus Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08173 | Ischemic hemorrhagic or vascular pathology indicator | IschHemVasclPathInd | Indicator of the presence of ischemic, hemorrhagic, or vascular pathology | Indicator of the presence of ischemic, hemorrhagic, or vascular pathology | Are there ischemic or hemorrhagic changes? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
If 'No' is answered for ischemic or hemorrhagic changes, skip to question 43. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18667 | Data source other text | DataSourcOTH | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15086 | Ischemic or hemorrhagic changes event category | IschHemChangesEventCat | Category of the ischemic or hemorrhagic changes | Category of the ischemic or hemorrhagic changes | Yes, present | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15022 | Brain atrophy nucleus coeruleus appearance grade | BrAtNucleusCoeruleusAppGrade | Grade of pigmentation of the nucleus coeruleus | Grade of pigmentation of the nucleus coeruleus | Nucleus coeruleus | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17756 | Striatum atrophy claustrum atrophy severity result | StrAtrophyClauAtrophySevReslt | Quantitative result of the severity of atrophy located in the claustrum | Quantitative result of the severity of atrophy located in the claustr | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15054 | Brain atrophy substantia nirgra pars compacta neuronal loss severity result | BrAtSubNiParsCoNeuLossSevReslt | Quantitative result of the severity of neuronal loss in the pars compacta | Quantitative result of the severity of neuronal loss in the pars compact | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15065 | Brain atrophy pons neuronal loss indicator | BrAtPonsNeurLossInd | Indicator of neuronal loss in the pons | Indicator of neuronal loss in the pon | Pons Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Pons: Neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14973 | Microscopical examination blocks source | MicroExamBlocksSource | The source of blockage based on microscopical examination of brain | The source of blockage based on microscopical examination of brain | Microscopical examination Source of blocks | Not available;Other, specify;Bilateral;Left half of brain;Right half of brain | Not available;Other, specify;Bilateral;Left half of brain;Right half of brain | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15097 | Single or multiple hemorrhages description text | SingMultiHemDescriptTxt | The text description of the hemorrhages | The text description of the hemorrhages | Describe | Alphanumeric |
Answer for each vascular territory and event category |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15033 | Brain atrophy amygdala neuronal loss indicator | BrAtAmygdalaNeurLossInd | Indicator of neuronal loss in the amygdala | Indicator of neuronal loss in the amygdal | Amygdala Neuronal Loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C06005 | Data collected date and time | DataCollDateTime | Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performed | Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performe | Date form completed | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
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| C08158 | Brain weight measurement | BrainWgtMeasr | Weight of the participant's/subject's brain in grams | Weight of the participant's/subject's brain in grams | Brain weight-Part weighed | Numeric Values |
This value should be recorded in grams (g) for all brain tissue weighed |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
gram | |||||||||
| C15076 | Brain atrophy cerebellum cortical neuronal loss in receptive layer severity result | BrAtCerCortNeuLosRecLaSevReslt | Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum | Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14984 | Brain atrophy coronal sections amygdala severity result | BrAtCorSecAmygdalaSevReslt | Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain | Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15108 | Diagnoses final clinicopathological severity scale | DiagnosFinClinicopathSevScale | Scale of the severity or intensity of the diagnosis | Scale of the severity or intensity of the diagnosis | Final Clinicopathological Diagnosis | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
Only answered if "Encephalopathy of hypoxic-ischemic type, acute", "Alzheimer changes", or "Status cribrosus and lacunaris" are answered for Final Clinicopathological diagnoses |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15044 | Brain atrophy thalamus neuronal loss severity result | BrAtThalamusNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the thalamus | Quantitative result of the severity of neuronal loss in the thalamus | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
This question is answered if "Yes, neuronal loss" is answered for 'Thalamus: neuronal loss" |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08175 | Cortical microinfarct indicator | CortclMicroinfarcInd | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Are there single or multiple cortical microinfarcts (each, <1.5cm in greatest dimension, including "granular atrophy")? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Cortical microinfarcts are defined as |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18669 | Diagnosis final clinical death other text | DiagnosFinalClinDeathOTH | The free-text field related to 'Diagnosis final clinical death type' specifying other text. Physician's final clinical diagnosis for the participant/subject | The free-text field related to 'Diagnosis final clinical death type' specifying other text. Physician's final clinical diagnosis for the participant/subject | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15087 | Ischemic or hemorrhagic vascular territories name | IschHemVasclTerritoriesName | Name of the vascular territories where ischemic or hemorrhagic changes occur | Name of the vascular territories where ischemic or hemorrhagic changes occur | Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) | ACA;MCA;PCA;Combined | ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15023 | Brain atrophy striatum brainstem status | BrAtStriatumBrainstemStat | Status of brainstem atrophy in the striatum | Status of brainstem atrophy in the striatu | Brainstem atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
Kemper TL. Neuroanatomical and Neuropathological changes during aging and dementia, Second edn., Oxford University Press, New York, 1994, 3-67. Esiri MM and Morris JH. Practical approach to pathological diagnosis. In: Esiri MM, Lee VM-Y, Trojanowski JQ, eds. The neuropathology of dementia. First ed. Cambridge CB2 2RU, UK: Cambridge University Press; 2004:48-74. | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17757 | Striatum atrophy hypothalamus atrophy status | StrAtrophyHypothAtrophyStat | Status of atrophy in the hypothalamus | Status of atrophy in the hypothalamu | Hypothalamus atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15055 | Brain atrophy substantia nigra pars reticulata neuronal loss indicator | BrAtSubNiParsReticNeurLosInd | Indicator of neuronal loss in the pars reticulata of the substantia nigra | Indicator of neuronal loss in the pars reticulata of the substantia nigr | Pars reticulata Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15066 | Brain atrophy pons neuronal loss severity result | BrAtPonsNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the pons | Quantitative result of the severity of neuronal loss in the pons | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Pons: Neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14974 | Brain atrophy surface status | BrainAtrophySurfStat | Status of cerebral atrophy on external surface of the brain upon gross examination | Status of cerebral atrophy on external surface of the brain upon gross examination | On gross examination of the external surface of the brain, cerebral atrophy | Absent;Present | Absent;Present | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15098 | Cortical laminar necrosis single or multiple event category | CortLaminNecSingMultiEvntCat | Category of the cortical laminar necrosis | Category of the cortical laminar necrosis | Yes | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15034 | Brain atrophy amygdala neuronal loss severity result | BrAtAmygdalaNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the amygdala | Quantitative result of the severity of neuronal loss in the amygdal | Yes, neuronal loss | 1+/4+;2+/4+;3+/4+;4+/4+ | 1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if 'Yes, neuronal loss' is answered for 'Amygdala neuronal loss' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08147 | Data source | DataSource | Source of the data provided on the case report form | Source of the data provided on the case report form | DATA SOURCE | Participant/subject;Mother;Father;Sister;Brother;Son;Daughter;Family, specify relation;Friend;Physician;Chart/Medical record;Other, specify;Unknown;Spouse | Participant/subject;Mother;Father;Sister;Brother;Son;Daughter;Family, specify relation;Friend;Physician;Chart/Medical record;Other, specify;Unknown;Spouse | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C08160 | Brain tissue weigh type | BrainTissWeighedTyp | Type of brain tissue weighed | Type of brain tissue weighed | Brain weight-Part weighed | Fresh whole brain;Fixed whole brain;Fixed not available;Other;Fixed left half;Fixed right half;Fresh left half;Fresh not available;Fresh right half | Fresh whole brain;Fixed whole brain;Fixed not available;Other;Fixed left half;Fixed right half;Fresh left half;Fresh not available;Fresh right half | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15077 | Brain atrophy cerebellum cortical neuronal loss in effective layer indicator | BrAtCerebCortNeurLossEffLayInd | Indicator of cortical neuronal loss in the effective layer (Purkinje cells) of the cerebellum | Indicator of cortical neuronal loss in the effective layer (Purkinje cells) of the cerebellum | Effective layer (Purknje cells) | No, neuronal loss;Yes, neuronal loss | No, neuronal loss;Yes, neuronal loss | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14985 | Brain atrophy striatum status | BrAtStriatumStat | Status of striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Status of striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15109 | Abnormality no diagnosis type | AbnrmlyNoDiagTyp | The diagnosis if there is no abnormality recognized | The diagnosis if there is no abnormality recognized | There is no diagnostic abnormality recognized | Control brain;Huntington disease, grade 0 | Control brain=If without neurological and psychiatric troubles, and without HD-IT15 CAG repeat expansion;Huntington disease, grade 0=If without neurological and psychiatric troubles, but with HD-IT15 CAG repeat expansion | Alphanumeric |
This question is answered only if "There is no diagnostic abnormality recognized" is answered for Final clinicopathological diagnosis. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15045 | Brain atrophy thalamus neuronal loss nuclei name | BrAtThalamusNeurLossNucName | Name of the nuclei in the thalamus involved in the neuronal loss | Name of the nuclei in the thalamus involved in the neuronal loss | If Yes, specify nuclei that are mainly involved | Motor nuclei ventral anterior;Motor nuclei ventral lateral;Centrum medianum;Limbic nuclei anterior;Limbic nuclei dorso-median;Other, specify | Motor nuclei ventral anterior;Motor nuclei ventral lateral;Centrum medianum;Limbic nuclei anterior;Limbic nuclei dorso-median;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C08176 | Lacunes single or multiple indicator | LacunesSingMultiInd | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels, most often in basal ganglia, thalamus, pons, cerebellum and cerebral white matter | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels, most often in basal ganglia, thalamus, pons, cerebellum and cerebral white matte | Are there single or multiple lacunes (each > 1,5cm, but = 2c, small artery infarcts | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Lacunes are defined as > 1.5cm each but = 2 cm small artery infarcts. |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18741 | Other pathology ischemic vascular disease specify text | OthrPathlgyIschmcVasclrDisST | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | Other, specify | Alphanumeric |
If yes, specify other |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
