CDE Detailed Report | NINDS Common Data Elements

Disease: Epilepsy
Subdomain Name: Classification
CRF: Classification of Seizures

Displaying 1 - 25 of 25

CDE ID	CDE Name	Variable Name	Definition	Short Description	Question Text	Permissible Values	Description	Data Type	Disease Specific Instructions	Disease Specific Reference	Population	Classification (e.g., Core)	Version Number	Version Date	CRF Name (CRF Module / Guidance)	Subdomain Name	Domain Name	Input Restrictions
C58607	Seizure epilepsy generalized subtype status	SeizEpilGenSubtypStat	The element related to the degree to which a generalized seizure is present	The element related to the degree to which a generalized seizure is present	Generalized Seizure Subtypes	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58583	Seizure epilepsy focal classification type	SeizEpilepsyFocClassTyp	The type of focal epileptic seizures, considered to originate within networks limited to one hemisphere, which may be discretely localized or more widely distributed, and may originate in subcortical structures, experience by the participant/subject	The type of focal epileptic seizures, considered to originate within networks limited to one hemisphere, which may be discretely localized or more widely distributed, and may originate in subcortical structures, experience by the participant/subjec	Focal Seizure Subtypes	Focal aware;Focal Impaired Awareness;Focal to bilateral, tonic clonic seizure;Focal, unknown awareness;Focal onset Clonic;Focal onset Tonic;Focal onset Atonic;Focal onset Epileptic spasm	Focal aware (without impairment of awareness);Focal Impaired Awareness (with impairment of awareness (roughly corresponds to the the concept of ''complex partial seizure''));Focal to bilateral, tonic clonic seizure (involving tonic, folowed by clonic movements, replaces the term ''secondarily generalized seizure'');Focal, unknown awareness;Focal onset Clonic;Focal onset Tonic;Focal onset Atonic;Focal onset Epileptic spasm	Alphanumeric	Per degree of impairment Tonic, clonic, atonic and epileptic spasm: When these seizure types occur in patients with combined focal and generalized epilepsy, it is often difficult to determine whether their onset is focal or generalized. Please use the Unknown Onset box in these cases. (e.g., Lennox Gastaut Syndrome). It is possible for a participant/subject to have more than one seizure type. For each seizure type, ictal onset is consistent from one seizure to another with preferential propagation patterns, which can involve the contralateral hemisphere. In some cases, however, there is more than one epileptogenic network, and more than one seizure type, but each individual seizure type has a consistent site of onset. Focal seizures do not fall into any recognized set of natural classes based on any current understanding of the mechanisms involved.	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522-530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531-542.	Adult;Pediatric	Supplemental-Highly Recommended	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Multiple Pre-Defined Values Selected
C58595	Seizure focal onset clonic present status	SeizFocOnsetClonicPresStat	The status indicating the degree to which a focal onset clonic seizure is present	The status indicating the degree to which a focal onset clonic seizure is present	Focal onset Clonic	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58584	Seizure focal aware present status	SeizFocAwarePresentStat	The status indicating the degree to which a focal aware seizure is present	The status indicating the degree to which a focal aware seizure is present	Focal aware	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	Without impairment of awareness No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58596	Seizure focal onset tonic present status	SeizFocOnsetTonicPresStat	The status indicating the degree to which a focal onset tonic seizure is present	The status indicating the degree to which a focal onset tonic seizure is present	Focal onset Tonic	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58585	Seizure focal aware motor present status	SeizFocAwareMotorPresentStat	The status indicating the degree to which a motor/observable focal aware seizure is present	The status indicating the degree to which a motor/observable focal aware seizure is present	Focal aware-motor/observable	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	With observable motor or autonomic components No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design With observable motor or autonomic components	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58597	Seizure focal onset atonic present status	SeizFocOnsetAtonicPresStat	The status indicating the degree to which a focal onset atonic seizure is present	The status indicating the degree to which a focal onset atonic seizure is present	Focal onset Atonic	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58586	Seizure focal aware non-motor present status	SeizFocAwareNonMotorPresStat	The status indicating the degree to which a non-motor focal aware seizure is present	The status indicating the degree to which a non-motor focal aware seizure is present	Focal aware-non-motor	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	Involving subjective sensory or psychic phenomena only No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58598	Seizure focal onset epileptic spasm present status	SeizFocOnsetEpilepSpasmPrsStat	The status indicating the degree to which a focal onset epileptic spasm seizure is present	The status indicating the degree to which a focal onset epileptic spasm seizure is present	Focal onset Epileptic spasm	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58588	Seizure focal impaired awareness present status	SeizFocImpairAwarePresentStat	The status indicating the degree to which a focal impaired awareness seizure is present	The status indicating the degree to which a focal impaired awareness seizure is present	Focal Impaired Awareness	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	With impairment of awareness (roughly corresponds to the concept of "complex partial seizure") Focal Impaired Awareness: This categorization should be used if a subject has focal seizure and they have confusion or difficulty understanding their environment or difficulty remembering what has occurred even in the absence of an altered level of consciousness. No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58599	Seizure epilepsy generalized classification type	SeizEpilepsyGenClassTyp	The type of generalized epileptic seizures, considered to originate at some point within, and rapidly engage, bilaterally distributed networks and may include such bilateral networks as cortical and subcortical structures, but do not necessarily include the entire cortex, experienced by the participant/subject	The type of generalized epileptic seizures, considered to originate at some point within, and rapidly engage, bilaterally distributed networks and may include such bilateral networks	Generalized Seizure Subtypes	Motor;Non-motor	Motor;Non-motor (absence)	Alphanumeric	Answer all. If a seizure cannot be adequately classified, it should not be fit into a category to which it does not belong. Specify type below It is possible for a participant/subject to have more than one seizure type. Although individual seizure onsets can appear localized, the location and lateralization are not consistent from one seizure to another. Generalized seizures can be asymmetric.	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522-530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531-542.	Adult;Pediatric	Supplemental-Highly Recommended	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58589	Seizure focal impaired awareness motor present status	SeizFocImpairAwareMtrPresStat	The status indicating the degree to which a motor/observable focal impaired awareness seizure is present	The status indicating the degree to which a motor/observable focal impaired awareness seizure is present	Focal impaired awareness-motor/observable	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	With observable motor or autonomic components Focal Impaired Awareness: This categorization should be used if a subject has focal seizure and they have confusion or difficulty understanding their environment or difficulty remembering what has occurred even in the absence of an altered level of consciousness. No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58600	Seizure epilepsy generalized motor subtype type	SeizEpilepsyGenMotorSubtypTyp	The element related to type of motor generalized seizures the participant/subject is experiencing	The element related to type of motor generalized seizures the participant/subject is experiencing	Motor:	Myoclonic-tonic-clonic;Clonic;Myoclonic;Tonic;Atonic;Generalized tonic-clonic;Epileptic spasms;Not otherwise specified	Myoclonic-tonic-clonic;Clonic;Myoclonic (not otherwise specified);Tonic;Atonic;Generalized tonic-clonic;Epileptic spasms;Not otherwise specified	Alphanumeric	Specify type. Tonic, clonic, atonic and epileptic spasm: When these seizure types occur in patients with combined focal and generalized epilepsy, it is often difficult to determine whether their onset is focal or generalized. Please use the Unknown Onset box in these cases. (e.g., Lennox Gastaut Syndrome).	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58590	Seizure focal impaired awareness non-motor present status	SeizFocImpAwareNonMtrPresStat	The status indicating the degree to which a non-motor focal impaired awareness seizure is present	The status indicating the degree to which a non-motor focal impaired awareness seizure is present	Focal Impaired Awareness-non-motor	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	Without observable motor or autonomic components Focal Impaired Awareness: This categorization should be used if a subject has focal seizure and they have confusion or difficulty understanding their environment or difficulty remembering what has occurred even in the absence of an altered level of consciousness. No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58601	Seizure epilepsy generalized non-motor subtype type	SeizEpilepsyGenNonMtrSubtypTyp	The element related to type of non-motor generalized seizures the participant/subject is experiencing	The element related to type of non-motor generalized seizures the participant/subject is experiencing	Non-motor	Absence NOS;Typical absence;Atypical absence;Myoclonic absence;Absence with eyelid myoclonia	Absence NOS (Not otherwise specified);Typical absence;Atypical absence;Myoclonic absence;Absence with eyelid myoclonia	Alphanumeric	(Absence) Specify type	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58591	Seizure focal bilateral tonic clonic present status	SeizFocBilatTonClonPresStat	The status indicating the degree to which a focal to bilateral, tonic clonic seizure is present	The status indicating the degree to which a focal to bilateral, tonic clonic seizure is present	Focal to bilateral, tonic clonic seizure	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	Involving tonic, followed by clonic movements, replaces the term "secondarily generalized seizure" No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58602	Seizure epilepsy unknown onset subtype status	SeizEpilUnknOnsetSubtypStat	The element related to the degree to which a seizure of unknown onset is present	The element related to the degree to which a seizure of unknown onset is present	Seizure subtypes of Unknown onset	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	Unknown if focal or generalized	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C06005	Data collected date and time	DataCollDateTime	Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performed	Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performe	Date form completed			Date or Date & Time	Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522-530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531-542.	Adult;Pediatric	Supplemental-Highly Recommended	3.00	2013-07-24 21:00:23.88	Classification of Seizures	Classification	Disease/Injury Related Events	Free-Form Entry
C58592	Seizure focal unknown aware present status	SeizFocUnknwnAwarePresStat	The status indicating the degree to which a focal, unknown awareness seizure is present	The status indicating the degree to which a focal, unknown awareness seizure is present	Focal, unknown awareness	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	If a seizure is definitely focal, but awareness is unknown, please use the Focal Unknown Awareness categorization No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58603	Seizure epilepsy unknown onset subtype type	SeizEpilepsyUnknOnsSubtypTyp	The element related to type of unknown onset seizures the participant/subject is experiencing	The element related to type of unknown onset seizures the participant/subject is experiencing	Seizure subtypes of Unknown onset	Generalized tonic-clonic;Motor NOS;Clonic;Tonic;Myoclonic;Atonic;Epileptic spasms;Non-motor NOS	Generalized tonic-clonic;Motor NOS (not otherwise specified);Clonic;Tonic;Myoclonic;Atonic;Epileptic spasms;Non-motor NOS (not otherwise specified)	Alphanumeric	Unknown if focal or generalized Tonic, clonic, atonic and epileptic spasm: When these seizure types occur in patients with combined focal and generalized epilepsy, it is often difficult to determine whether their onset is focal or generalized. Please use the Unknown Onset box in these cases. (e.g., Lennox Gastaut Syndrome).	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C14134	Data valid through date and time	DataValidThroughDateTime	Date (and time, if applicable and known) the data collected are valid through	Date the data collected are valid through	Information complete up to			Date or Date & Time	Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).		Adult;Pediatric	Supplemental-Highly Recommended	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Free-Form Entry
C58593	Seizure focal unknown awareness observable motor present status	SeizFocUnkAwarObsvMtrPresStat	The status indicating the degree to which a focal, unknown awareness seizure with observable motor is present	The status indicating the degree to which a focal, unknown awareness seizure with observable motor is present	With observable motor	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58604	Seizure unclassified classification status	SeizUnclassClassStat	The element related to the degree to which unclassified seizures are present	The element related to the degree to which unclassified seizures are present	Seizure type is unclassified:	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522-530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531-542.	Adult;Pediatric	Supplemental-Highly Recommended	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected
C58581	Seizure epilepsy classification type	SeizEpilepsyClassTyp	The type of epileptic seizure(s) the participant/subject experiences	The type of epileptic seizure(s) the participant/subject experiences	Classification of seizures	Generalized;Focal;Unclassified;Unknown if generalized or focal	Generalized;Focal;Unclassified seizures are considered unidentifiable due to lack of data and do not fit in to the aforementioned categories for Generalized and Focal Seizures;Unknown if generalized or focal	Alphanumeric	Check all that apply. It is possible for a participant/subject to have more than one seizure type. Focal - complete questions for focal seizure subtypes Generalized - complete questions for Generalized seizure subtypes Unclassified - complete questions for Unclassified seizure subtype	https://www.ilae.org/<br />Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Core	3.00	2013-08-28 16:08:00.453	Classification of Seizures	Classification	Disease/Injury Related Events	Multiple Pre-Defined Values Selected
C58594	Seizure focal unknown awareness no observable motor present status	SeizFocUnkAwarNoObsvMtrPrsStat	The status indicating the degree to which a focal, unknown awareness seizure without observable motor is present	The status indicating the degree to which a focal, unknown awareness seizure without observable motor is present	Without observable motor	No;Possible;Definite;Unknown;N/A;Probably	No;Possible;Definite;Unknown;N/A;Probably	Alphanumeric	No = Not present Possible = The summary of evidence suggests less than 50% confidence level Probable = The summary of evidence suggests greater than 50% confidence level Definite = The summary of evidence suggests 100% confidence level Unknown = The summary of evidence is not sufficient to support a finding N/A = Not Applicable; to be used at the discretion of the Principal Investigator based on study design	Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia 2017;58(4):522–530. <br />Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, MoshÉ SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–542.	Adult;Pediatric	Supplemental	3.00	2013-07-30 14:29:49.047	Classification of Seizures	Classification	Disease/Injury Related Events	Single Pre-Defined Value Selected