CDE Detailed Report
Disease: Myasthenia Gravis
Subdomain Name: History of Disease/Injury Event
CRF: Medical History of MG - MG
Displaying 1 - 14 of 14
Subdomain Name: History of Disease/Injury Event
CRF: Medical History of MG - MG
Displaying 1 - 14 of 14
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C08006 | Symptoms first appear date and time | SymptmFirstAppearDateTime | Date (and time if applicable and known) the symptoms for the disease or disorder first appeared as confirmed by the participant's/subject's medical history obtained by a physician | Date (and time if applicable and known) the symptoms for the disease or disorder first appeared as confirmed by the participant's/subject's medical history obtained by a physician | Date of first symptoms | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
No references available | Adult;Pediatric | Core | 3.10 | 2022-06-01 10:41:43.0 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
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| C12651 | Oosterhuis score | OosterhiusScore | Oosterhuis score for Myasthenia Gravis | Oosterhuis score for myasthenia gravis | Oosterhius score | 0;1;2;3;4;5 | Remission, no medication;Minimal signs and sympotms;Mildly disabled;Moderately disabled;Severely disabled;Respiratory supported needed | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Oosterhuis HJGH. The natural course of myasthenia gravis: a long-term followup study. J Neurol Neurosurg Psychiatry 1989;52:1121-1127. Oosterhuis HJ. Myasthenia gravis. A survey. Clin Neurol Neurosurg 1981;83:105-35. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Single Pre-Defined Value Selected |
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| C08007 | Diagnosis first given date and time | DiagnosFirstGivnDateTime | Date (and time if applicable and known) the participant/subject was initially diagnosed with the disease or disorder | Date (and time if applicable and known) the participant/subject was initially diagnosed with the disease or disorder | Date of diagnosis | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
No references available | Adult;Pediatric | Core | 3.00 | 2013-07-24 11:38:01.2 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
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| C18802 | Symptom first experienced other text | SymptmFirstExpOTH | The free-text field related to 'Symptom first experienced text' specifying other text. First symptom of the disease/disorder experienced by the participant/subject | The free-text field related to 'Symptom first experienced text' specifying other text. First symptom of the disease/disorder experienced by the participant/subject | What were the first symptoms | Alphanumeric |
Describe using free text the first symptom(s) that appeared |
No references available | Adult;Pediatric | Core | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events | 4000 |
Free-Form Entry |
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| C12642 | Symptom first experienced distribution category | SymptmFirstExpDistrCat | System or region of the body that exhibited the first symptoms of the disease/disorder | System or region of the body that exhibited the first symptoms of the disease/disorder | Initial distribution of symptoms | Ocular;Limb;Bulbar;Respiratory;Other, specify | Ocular;Limb;Bulbar;Respiratory;Other, specify | Alphanumeric |
Choose all that apply |
No references available | Adult;Pediatric | Core | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Multiple Pre-Defined Values Selected |
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| C18865 | Symptom first experienced distribution other text | SymptmFirstExpDistrOTH | The free-text field related to 'Symptom first experienced distribution category' specifying other text. System or region of the body that exhibited the first symptoms of the disease/disorder | The free-text field related to 'Symptom first experienced distribution category' specifying other text. System or region of the body that exhibited the first symptoms of the disease/disorder | Other, specify | Alphanumeric |
Choose all that apply |
No references available | Adult;Pediatric | Core | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events | 4000 |
Free-Form Entry |
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| C12643 | Myasthenia Gravis Foundation of America (MGFA) classification type | MGFAClassTyp | The Myasthenia Gravis Foundation of America (MGFA) classification of the maximum severity of Myasthenia Gravis symptoms | The Myasthenia Gravis Foundation of America (MGFA) classification of the maximum severity of Myasthenia Gravis symptoms | MGFA class | Class I;Class IIa;Class IIb;Class IIIa;Class IIIb;Class IVa;Class IVb;Class V | Class I;Class IIa;Class IIb;Class IIIa;Class IIIb;Class IVa;Class IVb;Class V | Alphanumeric |
Choose one |
No references available | Adult;Pediatric | Core | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Single Pre-Defined Value Selected |
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| C12644 | Institute of Neurology Carlo Besta (INNCB) Myasthenia Gravis scale - total score | INNCBMGScaleTotalScore | Participant/Subject's total score for the Fondazione Istituto Neurologico "Carlo Besta" (INNCB) Myasthenia Gravis Scale | Participant/Subject's total score for the Fondazione Istituto Neurologico "Carlo Besta" (INNCB) Myasthenia Gravis Scale | INNCB MG scale | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
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| C12645 | Institute of Neurology Carlo Besta (INNCB) Myasthenia Gravis scale - muscle fatigue score | INNCBMGScalMuScaleFatigScore | Participant/Subject's Muscle fatigability score for the Fondazione Istituto Neurologico "Carlo Besta" (INNCB) Myasthenia Gravis Scale | Participant/Subject's Muscle fatigability score for the Fondazione Istituto Neurologico "Carlo Besta" (INNCB) Myasthenia Gravis Scale | Muscle fatigability score | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
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| C12646 | Quantitative Myasthenia Gravis (QMG) - score | QMGScore | Participant/Subject's Quantitative Myasthenia Gravis (QMG) score (0-39) | Participant/Subject's Quantitative Myasthenia Gravis (QMG) score (0-39) | QMG score | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Jaretzki A, III, Barohn RB, Ernstoff RM, Kaminski HJ, Keesey JC, Penn AS, et al. Myasthenia gravis: recommendations for clinical research standards. Neurology 2000; vol 55:16-23. Wolfe GI, Herbelin LL, Nations SP, et al. Myasthenia gravis activity of daily living profile. Neurology 1999; 52:1487-1489. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
0 | 39 | ||||||||
| C12647 | Myasthenia gravis muscle manual testing (MG-MMT) - score | MGMMTScore | Participant/subject's score on the Myasthenia gravis muscle manual testing (MG-MMT) | Participant/subject's score on the Myasthenia gravis muscle manual testing (MG-MMT) | MG-MMT Score | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Sanders DB, Tucker-Lipscomb B, Massey JM. A simple manual muscle test for myasthenia gravis: validation and comparison with the QMG score. Ann N Y Acad Sci. 2003 Sep;998:440-4. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
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| C12648 | Myasthenia gravis composite score | MGCompositeScore | Participant/Subject's Myasthenia Gravis (MG) Composite score (0-50) | Participant/Subject's Myasthenia Gravis (MG) Composite score (0-50) | MG composite | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Burns TM, Conaway M, Sanders DB; MG Composite and MG-QOL15 Study Group. The MG Composite: A valid and reliable outcome measure for myasthenia gravis. Neurology. 2010 May 4;74(18):1434-40. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
0 | 50 | ||||||||
| C12649 | Myasthenia Gravis Activities of Daily Living (MG-ADL) - score | MGADLScore | Participant/Subject's Myasthenia Gravis Activities of Daily Living (MG-ADL) score (0-24) | Participant/Subject's Myasthenia Gravis Activities of Daily Living (MG-ADL) score (0-24) | MG ADL score | Numeric Values |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Muppidi S, Wolfe GI, Conaway M, Burns TM; MG-ADL: still a relevant outcome measure.; Muscle Nerve; 2011 Nov; 44(5); 727-731 | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Free-Form Entry |
0 | 24 | ||||||||
| C12650 | Osserman classification type | OssermanClassTyp | Osserman classification of Myasthenia Gravis | Osserman classification of myasthenia gravis | Osserman classification | I;IIA;IIB;drug response less than satisfactory;III;IV | Ocular myasthenia;Mild generalized myasthenia with slow progression: no crises, responsive to drugs;Moderately severe generalized myasthenia : severe skeletal and bulbar involvement but no crises;;Acute fulminating myasthenia, rapid progression of severe symptoms, with respiratory crises and poor drug response;Late severe myasthenia, same as III but progression over 2 years from class I to II | Alphanumeric |
Taken at the maximum severity of Myasthenia Gravis symptoms |
Ossermann KE. Myasthenia gravis. New York: Grune and Stratton; 1958. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 21:00:23.88 | Medical History of MG - MG | History of Disease/Injury Event | Disease/Injury Related Events |
Single Pre-Defined Value Selected |
