CDE Detailed Report

Disease: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Subdomain Name: Fatigue
CRF: Modified Fatigue Impact Scale (MFIS)

Displaying 1 - 30 of 30
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C11915 Modified Fatigue Impact Scale (MFIS) - less motivate physical effort score MFISLessMotivtePhysEffortScore Scale for having been less motivated to do anything that requires physical effort as part of Modified Fatigue Impact Scale form Scale for having been less motivated to do anything that requires physical effort as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been less motivated to do anything that requires physical effort 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11926 Modified Fatigue Impact Scale (MFIS) - think slow down score MFISThinkSlowDownScore Scale for slowed down thinking as part of Modified Fatigue Impact Scale form Scale for slowed down thinking as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, my thinking has been slowed down 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C17827 Modified Fatigue Impact Scale-5-Item Version (MFIS-5) - trouble concentrating scale MFIS5TroubConcntrScale Scale for having had trouble concentrating as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Scale for having had trouble concentrating as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Because of my fatigue during the past 4 weeks, I have had trouble concentrating 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11916 Modified Fatigue Impact Scale (MFIS) - less motivate social activity score MFISLessMotivateSocialActScore Scale for having been less motivated to participate in social activities as part of Modified Fatigue Impact Scale form Scale for having been less motivated to participate in social activities as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been less motivated to participate in social activities 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11927 Modified Fatigue Impact Scale (MFIS) - trouble concentrate score MFISTroubleConcentrateScore Scale for having had trouble concentrating as part of Modified Fatigue Impact Scale form Scale for having had trouble concentrating as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had trouble concentrating 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C17828 Modified Fatigue Impact Scale-5-Item Version (MFIS-5) - trouble maintaining long physical effort scale MFIS5TroubMaintLngPhyEffrtScl Scale for having had trouble maintaining physical effort for long periods as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Scale for having had trouble maintaining physical effort for long periods as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Because of my fatigue during the past 4 weeks, I have had trouble maintaining physical effort for long periods 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11917 Modified Fatigue Impact Scale (MFIS) - limit ability activity away from home score MFISLtdAbltyActAwayFrmHmScore Scale for having been limited in the ability to do things away from home as part of Modified Fatigue Impact Scale form Scale for having been limited in the ability to do things away from home as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been limited in my ability to do things away from home 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11928 Modified Fatigue Impact Scale (MFIS) - limit physical activity score MFISLimitPhysActsScore Scale for having limited physical activities as part of Modified Fatigue Impact Scale form Scale for having limited physical activities as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have limited my physical activities 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11918 Modified Fatigue Impact Scale (MFIS) - trouble maintain physical effort long time score MFISTblMaintnPhysEfrtLngTimScr Scale for having had trouble maintaining physical effort for long periods as part of Modified Fatigue Impact Scale form Scale for having had trouble maintaining physical effort for long periods as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had trouble maintaining physical effort for long periods 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11929 Modified Fatigue Impact Scale (MFIS) - rest more often longer score MFISRestMoreOftenLongerScore Scale for having needed to rest more often or for longer periods as part of Modified Fatigue Impact Scale form Scale for having needed to rest more often or for longer periods as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have needed to rest more often or for longer periods 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11919 Modified Fatigue Impact Scale (MFIS) - difficult make decision score MFISDifficultMakeDecisionScore Scale for having had difficulty making decisions as part of Modified Fatigue Impact Scale form Scale for having had difficulty making decisions as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had difficulty making decisions 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11930 Modified Fatigue Impact Scale (MFIS) - physical sub score MFISPhysSubScore Sum of MFIS Physical items (range: 0-36) Sum of MFIS Physical items (range: 0-36) Numeric Values

This scale can range from 0-36. It is computed by adding raw scores on the following items: 4+6+7+10+13+14+17+20+21.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Free-Form Entry

0 36
C11909 Modified Fatigue Impact Scale (MFIS) - less alert score MFISLessAlertScore Scale for being less alert as part of Modified Fatigue Impact Scale form Scale for being less alert as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been less alert 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11920 Modified Fatigue Impact Scale (MFIS) - less motivate activity require think score MFISLessMotivatActReqsThinkScr Scale for having been less motivated to do anything that requires thinking as part of Modified Fatigue Impact Scale form Scale for having been less motivated to do anything that requires thinking as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been less motivated to do anything that requires thinking 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11931 Modified Fatigue Impact Scale (MFIS) - cognitive score MFISCognitiveSubScore Sum of MFIS Cognitive items (range: 0-40) Sum of MFIS Cognitive items (range: 0-40) Numeric Values

This scale can range from 0-40. It is computed by adding raw scores on the following items: 1+2+3+5+11+12+15+16+18+19.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Free-Form Entry

0 40
C11910 Modified Fatigue Impact Scale (MFIS) - difficulty pay attention long period score MFISDffcltyPayAttnLngPerdScore Scale for having difficulty paying attention for long periods of time as part of Modified Fatigue Impact Scale form Scale for having difficulty paying attention for long periods of time as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had difficulty paying attention for long periods of time 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11921 Modified Fatigue Impact Scale (MFIS) - muscle weak score MFISMuScaleeWeakScore Scale for feeling weak in muscles as part of Modified Fatigue Impact Scale form Scale for feeling weak in muscles as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, my muscles have felt weak 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11932 Modified Fatigue Impact Scale (MFIS) - psychosocial score MFISPsychosocialSubScore Sum of MFIS Psychosocial items (range: 0-8) Sum of MFIS Psychosocial items (range: 0-8) Numeric Values

This scale can range from 0-8. It is computed by adding raw scores on the following items: 8+9

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Free-Form Entry

0 8
C11911 Modified Fatigue Impact Scale (MFIS) - unable think clearly score MFISUnableThinkClearlyScore Scale of having been unable to think clearly as part of Modified Fatigue Impact Scale form Scale of having been unable to think clearly as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been unable to think clearly 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11922 Modified Fatigue Impact Scale (MFIS) - physical uncomfort score MFISPhysUncomfortScore Scale for having been physically uncomfortable as part of Modified Fatigue Impact Scale form Scale for having been physically uncomfortable as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been physically uncomfortable 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11933 Modified Fatigue Impact Scale (MFIS) - total score MFISTotalScore Total MFIS score (range: 0-84) Total MFIS score (range: 0-84) Numeric Values

The Total MFIS score can range from 0-84. It is computed by adding scores on the Physical+Cognitive+Psychosocial subscales.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Free-Form Entry

0 84
C11912 Modified Fatigue Impact Scale (MFIS) - clumsy uncoordinated score MFIScaleumsyUncoordinatedScore Scale for having been clumsy and uncoordinated as part of Modified Fatigue Impact Scale form Scale for having been clumsy and uncoordinated as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been clumsy and uncoordinated as part of Modified Fatigue Impact Scale form 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11923 Modified Fatigue Impact Scale (MFIS) - trouble finish task require think score MFISTrblFinshTaskReqThinkScore Scale for having had trouble finishing tasks that require thinking as part of Modified Fatigue Impact Scale form Scale for having had trouble finishing tasks that require thinking as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had trouble finishing tasks that require thinking 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C17824 Modified Fatigue Impact Scale-5-Item Version (MFIS-5) - less able complete tasks requiring physical effort scale MFIS5LssAblCmpTskRqPhyEfrtScl Scale for having been less able to complete tasks that require physical effort as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Scale for having been less able to complete tasks that require physical effort as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Because of my fatigue during the past 4 weeks, I have been less able to complete tasks that require physical effort 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11913 Modified Fatigue Impact Scale (MFIS) - forgetful score MFISForgetfulScore Scale for having been forgetful as part of Modified Fatigue Impact Scale form Scale for having been forgetful as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been forgetful 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11924 Modified Fatigue Impact Scale (MFIS) - difficult organize thought home work score MFISDffcltOrgnizThoghtHmWrkScr Scale for having had difficulty organizing thoughts when doing things at home or at work as part of Modified Fatigue Impact Scale form Scale for having had difficulty organizing thoughts when doing things at home or at work as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had difficulty organizing my thoughts when doing things at home or at work 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C17825 Modified Fatigue Impact Scale-5-Item Version (MFIS-5) - less alert scale MFIS5LessAlertScale Scale for being less alert as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Scale for being less alert as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Because of my fatigue during the past 4 weeks, I have been less alert 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11914 Modified Fatigue Impact Scale (MFIS) - pace physical activity score MFISPacePhysActScore Scale for having paced self in the physical activities as part of Modified Fatigue Impact Scale form Scale for having paced self in the physical activities as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have had to pace myself in my physical activities 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C11925 Modified Fatigue Impact Scale (MFIS) - unable complete task physical effort score MFISUnablCmpletTaskPhysEfrtScr Scale for having been less able to complete tasks that require physical effort as part of Modified Fatigue Impact Scale form Scale for having been less able to complete tasks that require physical effort as part of Modified Fatigue Impact Scale form Because of my fatigue during the past 4 weeks, I have been less able to complete tasks that require physical effort 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values

Fatigue is a feeling of physical tiredness and lack of energy that many people experience from time to time. Choose the one number that best indicates how often fatigue has affected you in this way during the past 4 weeks. If you are not sure which answer to select, please choose the one answer that comes closest to describing you.

Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

C17826 Modified Fatigue Impact Scale-5-Item Version (MFIS-5) - limited ability away home scale MFIS5LimtAbilityAwyHomeScale Scale for having been limited in the ability to do things away from home as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Scale for having been limited in the ability to do things away from home as part of Modified Fatigue Impact Scale 5-Item Version (MFIS-5) form Because of my fatigue during the past 4 weeks, I have been limited in my ability to do things away from home 0;1;2;3;4 Never;Rarely;Sometimes;Often;Almost Always Numeric Values Fischer JS, Rudick RA, Cutter GR, Reingold SC. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult Scler. 1999 Aug;5(4):244-50. The consortium of multiple sclerosis centers health services research subcommittee. Multiple sclerosis quality of life inventory: a user's manual. National Multiple Sclerosis Society. 1997. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray TJ. The impact of fatigue on patients with multiple sclerosis. Can J Neurol Sci. 1994 Feb; 21(1): 9-14. Adult Exploratory 3.00 2013-07-22 16:57:17.79 Modified Fatigue Impact Scale (MFIS) Fatigue Outcomes and End Points

Single Pre-Defined Value Selected

CSV