CDE Detailed Report
Disease: Amyotrophic Lateral Sclerosis
Subdomain Name: Cognitive
CRF: Hamilton Depression Rating Scale (HDRS)
Displaying 1 - 19 of 19
Subdomain Name: Cognitive
CRF: Hamilton Depression Rating Scale (HDRS)
Displaying 1 - 19 of 19
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C09358 | Hamilton Depression Rating Scale (HDRS) - depressed mood indicator | HDRSDeprsdMdInd | Score for whether, how, and in what circumstances the participant/subject expresses feelings of depression (sadness, hopeless, helpless, worthless), as part of the Hamilton Depression Rating Scale (HDRS) | Score for whether, how, and in what circumstances the participant/subject expresses feelings of depression (sadness, hopeless, helpless, worthless), as part of the Hamilton Depression Rating Scale (HDRS) | Depressed mood (sadness, hopeless, helpless, worthless) | 0;1;2;3;4 | Absent;These feeling states indicated only on questioning;These feeling states spontaneously reported verbally;Communicates feeling states non-verbally, i.e. through facial expression, posture, voice and tendency to weep;Patient reports virtually only these feeling states in his/her spontaneous verbal and non-verbal communication | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09369 | Hamilton Depression Rating Scale (HDRS) - suicide indicator | HDRSucdInd | Score for the presence, qualities, and strength of the participant/subject's suicide-relevant thoughts and actions , if any, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the presence, qualities, and strength of the participant/subject's suicide-relevant thoughts and actions, if any, as part of the Hamilton Depression Rating Scale (HDRS) | Suicide | 0;1;2;3;4 | Absent;Feels life is not worth living;Wishes he/she were dead or any thoughts of possible death to self;Ideas or gestures of suicide;Attempts at suicide (any serious attempt rate 4) | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09359 | Hamilton Depression Rating Scale (HDRS) - anxiety psychic difficulty indicator | HDRSAnxPsycDifcltInd | Score for the participant/subject's degree of psychic anxiety, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's degree of psychic anxiety, as part of the Hamilton Depression Rating Scale (HDRS) | Anxiety psychic | 0;1;2;3;4 | No difficulty;Subjective tension and irritability;Worrying about minor matters;Apprehensive attitude apparent in face or speech;Fears expressed without questioning | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09370 | Hamilton Depression Rating Scale (HDRS) - early night insomnia indicator | HDRSErlyNgtInsmnInd | Score for the participant/subject's difficulty, if any, with early-night insomnia, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's difficulty, if any, with early-night insomnia, as part of the Hamilton Depression Rating Scale (HDRS) | Insomnia: early in the night | 0;1;2 | No difficulty falling asleep;Complains of occasional difficulty falling asleep, i.e. more than 1/2 hour;Complains of nightly difficulty falling asleep | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09360 | Hamilton Depression Rating Scale (HDRS) - anxiety somatic indicator | HDRSAnxSomtcInd | Score for the participant/subject's grade of symptoms of somatic anxiety, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's grade of symptoms of somatic anxiety, as part of the Hamilton Depression Rating Scale (HDRS) | Anxiety somatic (physiological concomitantsof anxiety) such as: gastro-intestinal - dry mouth, wind, indigestion, diarrhea, cramps, belching; cardio-vascular - palpitations, headaches; respiratory - hyperventilation, sighing; urinary frequency; sweating | 0;1;2;3;4 | Absent;Mild;Moderate;Severe;Incapacitating | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09371 | Hamilton Depression Rating Scale (HDRS) - middle night insomnia indicator | HDRSMddlNgtInsmnInd | Score for the participant/subject's difficulty, if any, with middle-night insomnia, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's difficulty, if any, with middle-night insomnia, as part of the Hamilton Depression Rating Scale (HDRS) | Insomnia: middle of the night | 0;1;2 | No difficulty;Complains of being restless and disturbed during the night;Waking during the night - any getting out of bed rates 2 (except for purposes of voiding) | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09361 | Hamilton Depression Rating Scale (HDRS) - somatic symptoms indicator | HDRSSomtcSymptmInd | Score for the intensity of the participant/subject's somatic gastrointestinal symptoms, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the intensity of the participant/subject's somatic gastrointestinal symptoms, as part of the Hamilton Depression Rating Scale (HDRS) | Somatic symptoms gastro-intestinal | 0;1;2 | None;Loss of appetite but eating without staff encouragement. Heavy feelings in abdomen;Difficulty eating without staff urging. Requests or requires laxatives or medication for bowels or medication for gastro-intestinal symptoms | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09372 | Hamilton Depression Rating Scale (HDRS) - early morning insomnia indicator | HDRSErlyMornInsmnInd | Score for the participant/subject's difficulty, if any, with insomnia in the early morning hours, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's difficulty, if any, with insomnia in the early morning hours, as part of the Hamilton Depression Rating Scale (HDRS) | Insomnia: early hours of the morning | 0;1;2 | No difficulty;Waking in early hours of the morning but goes back to sleep;Unable to fall asleep again if he/she gets out of bed | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09362 | Hamilton Depression Rating Scale (HDRS) - general somatic symptoms indicator | HDRSGenrlSomtcSymptmInd | Score for the intensity of the participant/subject's general somatic symptoms, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the intensity of the participant/subject's general somatic symptoms, as part of the Hamilton Depression Rating Scale (HDRS) | General somatic symptoms | 0;1;2 | None;Heaviness in limbs, back, or head. Backaches, headaches, muscle aches. Loss of energy and fatigability;Any clear-cut symptom rates 2 | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09373 | Hamilton Depression Rating Scale (HDRS) - work activities difficulty indicator | HDRSWrkActDifcltInd | Score for the participant/subject's difficulty, if any, with work and activities, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's difficulty, if any, with work and activities, as part of the Hamilton Depression Rating Scale (HDRS) | Work and activities | 0;1;2;3;4 | No difficulty;Thoughts and feelings of incapacity, fatigue or weakness related to activities, work or hobbies;Loss of interest in activity, hobbies, or work - either directly reported by the patient or indirect in listlessness, indecision and vacillation (feels he/she has to push self to work or activities);Decrease in actual time spent in activities or decrease in productivity. Rate 3 if the patient does not spend at least three hours a day in activities (job or hobbies) excluding routine chores;Stopped working because of present illness. Rate 4 if patient engages in no activities except routine chores, or if patient fails to perform routine chores unassisted. | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09363 | Hamilton Depression Rating Scale (HDRS) - genital symptoms indicator | HDRSGentlSymptmInd | Score for the intensity of the participant/subject's genital symptoms such as loss of libido or menstrual disturbances, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the intensity of the participant/subject's genital symptoms such as loss of libido or menstrual disturbances, as part of the Hamilton Depression Rating Scale (HDRS) | Genital symptoms(symptoms such as loss of libido, menstrual disturbances) | 0;1;2 | Absent;Mild;Severe | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09374 | Hamilton Depression Rating Scale (HDRS) - retardation indicator | HDRSRetrdtnInd | Score for any retardation in the participant/subject's mental or physical behavior, as part of the Hamilton Depression Rating Scale (HDRS) | Score for any retardation in the participant/subject's mental or physical behavior, as part of the Hamilton Depression Rating Scale (HDRS) | Retardation (slowness of thought and speech, impaired ability to concentrate, decreased motor activity) | 0;1;2;3;4 | Normal speech and thought;Slight retardation during the interview;Obvious retardation during the interview;Interview difficult;Complete stupor | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09364 | Hamilton Depression Rating Scale (HDRS) - hypochondriasis indicator | HDRSHypchdssInd | Score for the intensity of the participant/subject's hypochondriasis, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the intensity of the participant/subject's hypochondriasis, as part of the Hamilton Depression Rating Scale (HDRS) | Hypochondriasis | 0;1;2;3;4 | Not present;Self-absorption (bodily);Preoccupation with health;Frequent complaints, requests for help, etc;Hypochondriacal delusions | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09375 | Hamilton Depression Rating Scale (HDRS) - agitation indicator | HDRSAgttnInd | Score for the extent of agitated behaviors the participant/subject displays, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the extent of agitated behaviors the participant/subject displays, as part of the Hamilton Depression Rating Scale (HDRS) | Agitation | 0;1;2;3;4 | None;Fidgetiness;Playing with hands, hair, etc;Moving about, can't sit still;Hand wringing, nail biting, hair-pulling, biting of lips | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09365 | Hamilton Depression Rating Scale (HDRS) - weight loss patient indicator | HDRSWgtLosPatInd | Score for the amount of weight loss reported by the participant/subject, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the amount of weight loss reported by the participant/subject, as part of the Hamilton Depression Rating Scale (HDRS) | Loss of weight according to the patient | 0;1;2;3 | No weight loss;Probable weight loss associated with present illness;Definite (according to patient) weight loss;Not assessed | Numeric Values |
Rate either HDRS Q16a or HDRSQ16b |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09376 | Hamilton Depression Rating Scale (HDRS) - total score | HDRSTotScore | Value of the sum of all scores recorded, as part of the Hamilton Depression Rating Scale (HDRS) | Value of the sum of all scores recorded, as part of the Hamilton Depression Rating Scale (HDRS) | Total Score | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Free-Form Entry |
0 | 53 | ||||||||
| C09366 | Hamilton Depression Rating Scale (HDRS) - weight loss measurement indicator | HDRSWgtLosMeasrInd | Score for the amount of the participant/subject's weight loss according to weekly measurements, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the amount of the participant/subject's weight loss according to weekly measurements, as part of the Hamilton Depression Rating Scale (HDRS) | Loss of weight according to weekly measurements | 0;1;2;3 | Less than 1 lb weight loss in week;Greater than 1 lb weight loss in week;Greater than 2 lb weight loss in week;Not assessed | Numeric Values |
Rate either HDRS Q16a or HDRSQ16b |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09367 | Hamilton Depression Rating Scale (HDRS) - insight indicator | HDRSInsgtInd | Score for the participant/subject's acknowledgement of depression and illness, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the participant/subject's acknowledgement of depression and illness, as part of the Hamilton Depression Rating Scale (HDRS) | Insight | 0;1;2 | Acknowledges being depressed and ill;Acknowledges illness but attributes cause to bad food, climate, overwork, virus, need for rest, etc;Denies being ill at all | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
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| C09368 | Hamilton Depression Rating Scale (HDRS) - guilty mind indicator | HDRSGltMndInd | Score for the presence, qualities, and strength of the participant/subject's guilty feelings, if any, as part of the Hamilton Depression Rating Scale (HDRS) | Score for the presence, qualities, and strength of the participant/subject's guilty feelings, if any, as part of the Hamilton Depression Rating Scale (HDRS) | Feelings of guilt | 0;1;2;3;4 | Absent;Self reproach, feels he/she has let people down;Ideas of guilt or rumination over past errors or sinful deeds;Present illness is a punishment. Delusions of guilt;Hears accusatory or denunciatory voices and/or experiences threatening visual hallucinations | Numeric Values |
for each item select the one "cue" which best characterizes the patient. Be sure to record the answers in the appropriate spaces (positions 0 through 4). |
Hamilton, M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62 The HDRS is in the public domain. | Adult | Exploratory | 3.00 | 2013-07-22 16:57:17.79 | Hamilton Depression Rating Scale (HDRS) | Cognitive | Outcomes and End Points |
Single Pre-Defined Value Selected |
