CDE Detailed Report

Disease: Amyotrophic Lateral Sclerosis
Sub-Domain: Cognitive
CRF: Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA)

Displaying 1 - 8 of 8
CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C11623 Center for Neurologic Study-Lability Scale (CNS-LS) - fine tearful scale CNSLSFineTearfulScale Scale used to measure the degree to which the participant/subject felt he became tearful over something small or for no reason during this past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt he became tearful over something small or for no reason during this past week, as part of the CNS-LS for PBA questionnaire. There are times when I feel fine 1 minute, and then I'll become tearful the next over something small or for no reason at all. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11624 Center for Neurologic Study-Lability Scale (CNS-LS) - amused easily not funny scale CNSLSAmsdEslyNtFnnyScale Scale used to measure the degree to which the participant/subject felt he became amused easily or were amused by things that weren't really funny during this past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt he became amused easily or were amused by things that weren't really funny during this past week, as part of the CNS-LS for PBA questionnaire. Others have told me that I seem to become amused very easily or that I seem to become amused about things that really aren't funny. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11625 Center for Neurologic Study-Lability Scale (CNS-LS) - crying easily scale CNSLSCryngEslyScale Scale used to measure the degree to which the participant/subject felt he found himself crying very easliy during this past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt he found himself crying very easily during this past week, as part of the CNS-LS for PBA questionnaire. I find myself crying very easily. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11626 Center for Neurologic Study-Lability Scale (CNS-LS) - laughter control inability scale CNSLSLaughContInabilityScale Scale used to measure the degree to which the participant/subject felt he found himself unable to control his laughter during this past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt he found himself unable to control his laughter during this past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. I find that even when I try to control my laughter, I am often unable to do so. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11627 Center for Neurologic Study-Lability Scale (CNS-LS) - thought funny happy overcome scale CNSLSThougFunnyHappyOverScale Scale used to measure the degree to which the participant/subject felt there were many times he could not think of anything happy or funny at all, but was overcame by funny or happy thoughts during the past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant felt there were many times he could not think of anything happy or funny at all, but was overcame by funny or happy thoughts during the past week, as part of the CNS-LS for PBA questionnaire. There are times when I won't be thinking of anything happy or funny at all, but then I'll suddenly be overcome by funny or happy thoughts. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11628 Center for Neurologic Study-Lability Scale (CNS-LS) - crying control inability scale CNSLSCryControlInabilityScale Scale used to measure the degree to which the participant/subject felt that he could not control his crying during the past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt that he could not control his crying during the past week, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. I find that even when I try to control my crying, I am often unable to do so. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11629 Center for Neurologic Study-Lability Scale (CNS-LS) - laughter overcome scale CNSLSLaughterOvercomeScale Scale used to measure the degree to which the participant/subject felt that he was easily overcame by laughter, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Scale used to measure the degree to which the participant/subject felt that he was easily overcame by laughter, as part of the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. I find that I am easily overcome by laughter. 1;2;3;4;5 Applies never;Applies rarely;Applies occasionally;Applies frequently;Applies most of the time Numeric Values

Please write the number that describes the degree to which each item applies to you DURING THE PAST WEEK. Write only 1 number for each item.

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

Single Pre-Defined Value Selected

C11630 Center for Neurologic Study-Lability Scale (CNS-LS) - total score CNSLSTotalScore Score of the sum of all the scaled answers the participant/subject indicated on the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Score of the sum of all the scaled answers the participant/subject indicated on the Center for Neurologic Study-Lability Scale (CNS-LS) for pseudobulbar affect (PBA) questionnaire. Total Score Numeric Values

Sum of Q1 - Q7

Moore SR, Gresham L, Bromberg MB, Kasarkis E, Smith RA (1997). A self report measure of affective lability. J. Neurol Neurosurg Psychiatry 1997;63:89-93. Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, and Smith RA (2004) Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology 63(8):1364-70. Adult Supplemental 3.00 2013-07-22 16:57:17.79 Center for Neurologic Study - Lability Scale for pseudobulbar affect (PBA) Cognitive Outcomes and End Points

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