CDE Detailed Report

Disease: Amyotrophic Lateral Sclerosis
Sub-Domain: Non-Imaging Diagnostics
CRF: Electrophysiology

Displaying 1 - 31 of 31
CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C18810 Electrical impedance myography method used other text EIMMethodUsedOTH The free-text field related to 'Electrical impedance myography method used type' specifying other text. Type of technique/method used for electrical impedance myography (EIM) The free-text field related to 'Electrical impedance myography method used type' specifying other text. Type of technique/method used for electrical impedance myography (EIM) Other, specify Alphanumeric

Choose one for each muscle site studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 4000

Free-Form Entry

C10778 Electrophysiology motor unit number estimation muscle studied name ElctPhysMUNEMuscleStudiedName Name of the muscle studied using the MUNE (motor unit number estimation) technique Name of the muscle studied using the MUNE (motor unit number estimation) technique Muscle Studied Alphanumeric

Record the muscle studied. It is recommended that three different muscle sites be examined.

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C10791 Electrical impedance myography muscle studied name EIMMuscleStudiedName Name of the muscle studied using electrical impedance myography (EIM) Name of the muscle studied using electrical impedance myography (EIM) Muscle Studied Alphanumeric

Record the muscle studied. It is recommended that five different muscle sites are examined.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C10779 Motor unit number estimation area weak indicator MUNEAreaWeakInd Indicator whether there is clinical evidence of muscle weakness in the muscle studied using the MUNE (motor unit number estimation) technique Indicator whether there is clinical evidence of muscle weakness in the muscle studied using the MUNE (motor unit number estimation) technique Area Weak Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one for each muscle site studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10793 Electrical impedance myography muscle weak indicator EIMMuscleWeakInd Indicator whether there is clinical evidence of muscle weakness using electrical impedance myography (EIM) Indicator whether there is clinical evidence of muscle weakness using electrical impedance myography (EIM) Muscle Weak Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one for each muscle site studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C02411 Laterality type LatTyp Laterality type relative to the anatomic site of the body examined or affected Laterality type relative to the anatomic site of the body examined or affected Side Bilateral;Left;Right;Unknown;Midline Bilateral;Left;Right;Unknown;Midline Alphanumeric

Use this element for all of the "EMG area studied anatomic sites" except Face and Thoracic"; Record whether the EIM results were for the right and/or left side of the muscle site

Kendall. Muscles: Testing and Function with Posture and Pain, 5th ed. Florence JM, Pandya S, King WM et al. Intrarater reliability of manual muscle test (Medical Research Council Scale) grades in Duchenne's muscular dystrophy. Phys Ther 1992;72:115-126. Adult;Pediatric Supplemental 3.00 2013-08-28 16:08:00.453 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10782 Electrophysiology motor unit number estimation method used type ElctphysMUNEMethdUseTyp Type of method or technique used for MUNE (motor unit number estimation) Type of method or technique used for MUNE (motor unit number estimation) Method Used Incremental;Multipoint;Statistical;Other, specify Incremental;Multipoint;Statistical;Other, specify Alphanumeric

Choose one for each muscle studied

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10794 Electrical impedance myography method used type EIMMethodUsedTyp Type of technique/method used for electrical impedance myography (EIM) Technique/method used for electrical impedance myography (EIM) Method Used Single frequency;Multifrequency;Other, specify Single frequency;Multifrequency;Other, specify Alphanumeric

Choose one for each muscle site studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10761 Electromyography area studied anatomic site EMGAreaStudiedAntmicSite Anatomic site where electrical activity of voluntary (skeletal) muscles are measured at rest and during voluntary action using electromyography (EMG) Anatomic site where electrical activity of voluntary (skeletal) muscles are measured at rest and during voluntary action using electromyography (EMG) Anatomic Area Studied Arm;Leg;Face;Thoracic;Tongue;Masseter;Biceps;Triceps;Extensor digitorum communis;Abductor pollicis brevis;Abductor Digiti Minimi;First dorsal interosseus;Paraspinal;Vastuslateralis;Tibialis anterior;Gastrocnemius;Tibialis posterior;Other, specify Arm;Leg;Face;Thoracic;Tongue;Masseter;Biceps;Triceps;Extensor digitorum communis (EDC);Abductor pollicis brevis (APB);Abductor Digiti Minimi (ADM);First dorsal interosseus (FDI);Paraspinal;Vastuslateralis;Tibialis anterior;Gastrocnemius;Tibialis posterior;Other, specify Alphanumeric

Record the results of the electromyography (EMG)/ nerve conduction studies (NCS) for each anatomic site.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10783 Electrophysiology motor unit number estimation compound muscle action potential measurement ElctphysMUNECMAPMeasr Measurement in millivolts (mV) of the compound muscle action potential (CMAP) amplitude for the muscle on which MUNE (motor unit number estimation) is performed Measurement in millivolts (mV) of the compound muscle action potential (CMAP) amplitude for the muscle on which MUNE (motor unit number estimation) is performed Compound Motor Action Potential Numeric Values

Record in millivolts (mV) for each muscle studied

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Free-Form Entry

milliVolt
C17781 Electrical impedance myography comment text EIMCommentTxt Text field for comments on the electrical impedance myography (EIM) performed Text field for comments on the electrical impedance myography (EIM) performed Comments Alphanumeric No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C10762 Electromyography area weak indicator EMGAreaWeakInd Indicator whether there is clinical evidence from electromyography (EMG) of muscle weakness in anatomical region studied Indicator whether there is clinical evidence from electromyography (EMG) of muscle weakness in anatomical region studied Area Weak Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer only for Right Arm, Left Arm, Right Leg, Left Leg and Face.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10784 Motor unit number estimation single motor unit potential measurement MUNESMUPMeasr Measurement in microvolts (?V) of the single motor unit potential (SMUP) amplitude, estimated using the designated MUNE (motor unit number estimation) technique Measurement in microvolts (?V) of the single motor unit potential (SMUP) amplitude, estimated using the designated MUNE (motor unit number estimation) technique Single Motor Unit Potential Amplitude Estimate (microV) Numeric Values

Record in microvolts (?V) for each muscle studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Free-Form Entry

microVolt
C17782 Electromyography comment text EMGCommentTxt Text field for comments on electromyography (EMG) on the specific anatomic site and side Text field for comments on electromyography (EMG) on the specific anatomic site and side Comments Alphanumeric No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C10763 Electromyography conduction block evidence indicator EMGConductionBlockEvidenceInd Indicator whether there are areas of focal conduction slowing or loss of compound motor action potential amplitude unexplained by nerve compression found by nerve conduction study (NCS) Indicator whether there are areas of focal conduction slowing or loss of compound motor action potential amplitude unexplained by nerve compression found by nerve conduction study (NCS) Evidence of Conduction Block Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer only for Right Arm, Left Arm, Right Leg and Left Leg.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10785 Electrophysiology motor unit number estimation value ElctphysMUNEVal Value of the motor unit number estimate (MUNE), derived by dividing compound muscle action potential (CMAP) amplitude by single motor unit potential (SMUP) amplitude Value of the motor unit number estimate (MUNE), derived by dividing compound muscle action potential (CMAP) amplitude by single motor unit potential (SMUP) amplitude Motor Unit Number Estimate Numeric Values

Record the calculated MUNE value for each muscle studied

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

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C17829 Motor unit number estimation site single motor unit potential value MUNESiteSMUPVal Value in microvolts of MUNE (motor unit number estimation) SMUP (single motor unit potential) for the muscle site studied Value in microvolts of MUNE (motor unit number estimation) SMUP (single motor unit potential) for the muscle site studied Site x SMUP Numeric Values

Equal to (=) 3rd amplitude / 3

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Free-Form Entry

microVolt
C10764 Electromyography fasciculations presence indicator EMGFasciculationsPresenceInd Indicator whether there are fasciculations present at rest in at least one muscle of the limb studied with electromyography (EMG) Indicator whether there are fasciculations present at rest in at least one muscle of the limb studied with electromyography (EMG) Presence of Fasciculations Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer for all areas studied.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10786 Electrophysiology motor unit number estimation nerve type ElctphysMUNENervTyp Type of nerve where an electrical signal is measured with the MUNE (motor unit number estimation) technique Type of nerve where an electrical signal is measured with the MUNE (motor unit number estimation) technique Axillary;Facial;Femoral;Mandibular;Maxillary;Median;Perineal;Radial;Sciatic;Tibial;Ulnar;Other, specify Axillary;Facial;Femoral;Mandibular;Maxillary;Median;Perineal;Radial;Sciatic;Tibial;Ulnar;Other, specify Alphanumeric

Record the CMAP and SMUP measurements for each nerve and side (right or left)

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C17865 Transcranial magnetic stimulation comments text TMSCommentsTxt Text field for comments on the transcranial magnetic stimulation (TMS) performed Text field for comments on the transcranial magnetic stimulation (TMS) performed Comments Alphanumeric No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C10765 Electromyography fibrillation positive waves presence indicator EMGFibPosWavesPresenceInd Indicator whether there are fibrillation potentials on electromyography (EMG) examination in at least one muscle of the limb studied Indicator whether there are fibrillation potentials on electromyography (EMG) examination in at least one muscle of the limb studied Presence of Fibrillation/Positive Waves Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer for all areas studied.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10787 MUNE area studied laterality type MUNEAreaStudLatTyp Side of the section of the body studied using the MUNE (motor unit number estimation) technique Side of the section of the body studied using the MUNE (motor unit number estimation) technique Alphanumeric

Record the CMAP and SMUP measurements for each nerve and side (right or left)

No references available Adult Supplemental 1.00 2012-08-31 00:00:00.0 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

Free-Form Entry

C18807 Electromyography area studied anatomic other text EMGAreaStudiedAntmicOTH The free-text field related to 'Electromyography area studied anatomic site' specifying other text. Anatomic site where electrical activity of voluntary (skeletal) muscles are measured at rest and during voluntary action using electromyography (EMG) The free-text field related to 'Electromyography area studied anatomic site' specifying other text. Anatomic site where electrical activity of voluntary (skeletal) muscles are measured at rest and during voluntary action using electromyography (EMG) Other, specify Alphanumeric

Record the results of the electromyography (EMG)/ nerve conduction studies (NCS) for each anatomic site.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 4000

Free-Form Entry

C10766 Electromyography neurogenic motor units evidence indicator EMGNeuroMotorUnitsEvidenceInd Indicator whether there are enlarged and prolonged motor units on electromyography (EMG) examination in at least one muscle of the limb studied Indicator whether there are enlarged and prolonged motor units on electromyography (EMG) examination in at least one muscle of the limb studied Evidence of Neurogenic Motor Units Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer for all areas studied.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10788 Motor unit number estimation average single motor unit potential value MUNEAvgSMUPVal Value of the average single motor unit potential (SMUP) amplitude, estimated using the designated MUNE (motor unit number estimation) technique Value of the average single motor unit potential (SMUP) amplitude, estimated using the designated MUNE (motor unit number estimation) technique Average SMUP Numeric Values

Calculate for a specific site by averaging three SMUP measurements. Calculate for a specific nerve by then averaging the average SMUP.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Free-Form Entry

C18808 Electrophysiology motor unit number estimation method used other text ElctphysMUNEMethdUseOTH The free-text field related to 'Electrophysiology motor unit number estimation method used type' specifying other text. Type of method or technique used for MUNE (motor unit number estimation) The free-text field related to 'Electrophysiology motor unit number estimation method used type' specifying other text. Type of method or technique used for MUNE (motor unit number estimation) Other, specify Alphanumeric

Choose one for each muscle studied

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 4000

Free-Form Entry

C10774 Electromyography normal results indicator EMGNormalResltsInd Indicator whether the electromyography (EMG) results are normal for the anatomic site and side studied Indicator whether the electromyography (EMG) results are normal for the anatomic site and side studied Normal Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer for the following anatomic sites on both sides (right and left): Tongue; Masseter; Cranial other, specify; Biceps; Triceps; EDC; APB; ADM; FDI; Cervical other, specify; Paraspinal; Thoracic other, specify; Vastuslateralis; Tibialis anterior; Gastrocnemius; Tibialis posterior; Lumbosacral other, specify.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10789 Transcranial magnetic stimulation muscle studied name TMSMuscleStudiedName Name of the muscle studied using transcranial magnetic stimulation (TMS) Name of the muscle studied using transcranial magnetic stimulation (TMS) MuscleRecorded Form (Free Text) Alphanumeric

Record the muscle studied. It is recommended that three different muscle sites be examined.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 255

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C18809 Electrophysiology motor unit number estimation nerve other text ElctphysMUNENervOTH The free-text field related to 'Electrophysiology motor unit number estimation nerve type' specifying other text. Type of nerve where an electrical signal is measured with the MUNE (motor unit number estimation) technique The free-text field related to 'Electrophysiology motor unit number estimation nerve type' specifying other text. Type of nerve where an electrical signal is measured with the MUNE (motor unit number estimation) technique Other, specify Alphanumeric

Record the CMAP and SMUP measurements for each nerve and side (right or left)

No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations 4000

Free-Form Entry

C10775 Electromyography not assessed indicator EMGNotAssessedInd Indicator whether the electromyography (EMG) was not performed on the specific anatomic site and side Indicator whether the electromyography (EMG) was not performed on the specific anatomic site and side Not Assessed Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. Answer for the following anatomic sites on both sides (right and left): Tongue; Masseter; Cranial other, specify; Biceps; Triceps; EDC; APB; ADM; FDI; Cervical other, specify; Paraspinal; Thoracic other, specify; Vastuslateralis; Tibialis anterior; Gastrocnemius; Tibialis posterior; Lumbosacral other, specify.

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

C10790 Transcranial magnetic stimulation muscle weak indicator TMSMuscleWeakInd Indicator whether there is clinical evidence of muscle weakness from the transcranial magnetic stimulation (TMS) Indicator whether there is clinical evidence of muscle weakness from the transcranial magnetic stimulation (TMS) Muscle Weak Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one for each muscle site studied

No references available Adult Supplemental 3.00 2013-07-22 16:57:17.79 Electrophysiology Non-Imaging Diagnostics Assessments and Examinations

Single Pre-Defined Value Selected

CSV