CDE Detailed Report

Disease: Mitochondrial Disease
Sub-Domain: Emotional/Behavioral
CRF: Hamilton Anxiety Rating Scale (HAM-A)

Displaying 1 - 14 of 14
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C09352 Hamilton Anxiety Rating Scale (HAM-A) - cardiovascular symptom score HAMACardiovascularSymptomScore The score of the participant's/subject's cardiovascular symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's cardiovascular symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Cardiovascular symptoms Tachycardia palpitations pain in chest throbbing of vessels fainting feelings missing beat. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09353 Hamilton Anxiety Rating Scale (HAM-A) - respiratory symptom score HAMARespiratorySymptomScore The score of the participant's/subject's respiratory symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's respiratory symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Respiratory symptoms Pressure or constriction in chest choking feelings sighing dyspnea. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09354 Hamilton Anxiety Rating Scale (HAM-A) - gastrointestinal symptom score HAMAGastrointestinalSymptomScr The score of the participant's/subject's gastrointestinal symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's gastrointestinal symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Gastronintestinal symptoms Difficulty in swallowing wind abdominal pain burning sensations abdominal fullness nausea vomiting borborygmi looseness of bowels loss of weight constipation. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09344 Hamilton Anxiety Rating Scale (HAM-A) - anxious mood score HAMAAnxiousMoodScore The score of the participant's/subject's anxious mood, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's anxious mood, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Anxious Mood Worries anticipation of the worst fearful anticipation irritability. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09355 Hamilton Anxiety Rating Scale (HAM-A) - genitourinary symptom score HAMAGenitourinarySymptomScore The score of the participant's/subject's genitourinary symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's genitourinary symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Genitourinary symptoms Frequency of micturition urgency of micturition amenorrhea menorrhagia development of frigidity premature ejaculation loss of libido impotence. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09345 Hamilton Anxiety Rating Scale (HAM-A) - fear score HAMAFearScore The score of the participant's/subject's fears, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's fears, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Fears Of dark of strangers of being left alone of animals of traffic or crowds. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09356 Hamilton Anxiety Rating Scale (HAM-A) - autonomic symptom score HAMAAutonomicSymptomScore The score of the participant's/subject's autonomic symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's autonomic symptoms, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Autonomic symptoms Dry mouth flushing pallor tendency to sweat giddiness tension headache raising of hair. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09346 Hamilton Anxiety Rating Scale (HAM-A) - insomnia score HAMAInsomniaScore The score of the participant's/subject's insomnia, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's insomnia, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Insomnia Difficulty in falling asleep broken sleep unsatisfying sleep and fatigue on waking dreams nightmares night terrors. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09357 Hamilton Anxiety Rating Scale (HAM-A) - behavior interview score HAMABehaviorInterviewScore The score of the participant's/subject's behavior at interview, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's behavior at interview, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Behavior at interview Fidgeting, restlessness or pacing tremor of hands furrowed brow strained face sighing or rapid respiration facial pallor swallowing, etc. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09347 Hamilton Anxiety Rating Scale (HAM-A) - intellectual score HAMAIntellectualScore The score of the participant's/subject's intellectual trouble, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's intellectual trouble, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Intellectual Difficulty in concentration poor memory. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09348 Hamilton Anxiety Rating Scale (HAM-A) - depressed mood score HAMADepressedMoodScore The score of the participant's/subject's depressed mood, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's depressed mood, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Depressed mood. Loss of interest lack of pleasure in hobbies depression early waking diurnal swing. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09349 Hamilton Anxiety Rating Scale (HAM-A) - somatic muscular score HAMASomaticMuscularScore The score of the participant's/subject's somatic (muscular) levels, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's somatic (muscular) levels, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Somatic muscular Pains and aches twitching stiffness myoclonic jerks grinding of teeth unsteady voice increased muscular tone. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09350 Hamilton Anxiety Rating Scale (HAM-A) - tension score HAMATensionScore The score of the participant's/subject's tension, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's tension, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Tension Feelings of tension fatigability startle response moved to tears easily trembling feelings of restlessness inability to relax. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

C09351 Hamilton Anxiety Rating Scale (HAM-A) - somatic sensory score HAMASomaticSensoryScore The score of the participant's/subject's somatic (sensory) levels, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. The score of the participant's/subject's somatic (sensory) levels, as part of the Hamilton Anxiety Rating Scale (HAM-A) form. Somatic sensory Tinnitus blurring of vision hot and cold flushes feelings of weakness pricking sensation. 0;1;2;3;4 Not present;Mild;Moderate;Severe;Very severe Numeric Values

Rate the patients by finding the answer which best describes the extent to which he/she has these conditions. Select one of the five responses for each of the fourteen questions.

The HAM-A is in the public domain. Hamilton M. The assessment of anxiety states by rating. Br J Medical Psychology 1959; 32: 50-55. Leentjens AFG et al. Anxiety rating scales in Parkinson's disease: a validation study of the Hamilton Anxiety Scale, the Beck Anxiety Inventory and the Hospital Anxiety and Depression Scale. In review. Shear MK, Vander BJ, Rucci P, Endicott J, Lydiard B, Otto MW et al (2001): Reliability and validity of a structured interview guide for the Hamilton Anxiety Rating Scale (SIGH-A). Depress.Anxiety. 13: 166-178. Leentjens AFG et al. Anxiety Rating Scales in Parkinson's Disease: Critique and Recommendations, Mov Disord 2008; 23 (14): 2015-2025. Adult Supplemental-Highly Recommended 3.00 2013-07-22 09:34:41.527 Hamilton Anxiety Rating Scale (HAM-A) Emotional/Behavioral Outcomes and End Points

Single Pre-Defined Value Selected

CSV