CDE Catalog

***Please contact NINDS CDE team (NINDSCDE@emmes.com) in case you encounter any search difficulties.***

The CDE Catalog is a directory of the available NINDS CDEs. Users can search the Catalog to isolate a subset of the CDEs (e.g., all stroke-specific CDEs, etc.), and to view and download details about the CDEs.

Select any filter below to search the CDE Catalog.

For best results, clear form between searches. In addition, when specifying NeuroRehab, Sport Related Concussion or Traumatic Brain Injury as the Disease, please select a Sub-Disease as well.

NeuroRehab Comprehensive includes all CDE recommendations.

NeuroRehab General includes all CDE recommendations that are not disease specific.

All other NeuroRehab Sub-Diseases include recommendations specific to existing NINDS CDE project disorders.

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Displaying 51 - 75 of 736
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The search results below can be downloaded by clicking the checkboxes on the far left side of the table. Select the header checkbox to select all CDEs listed on the first page. Then choose CDE Detailed Report from the Choose an operation dropdown menu.
CDE ID CDE Name Definition Classification CRF Name Copyrighted or trademarked Disease Name Sub Disease Name
C12265 Biopsy and autopsy diagnostic abnormalities severity grade

Severity of the diagnostic muscle abnormalities

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12256 Biopsy and autopsy eccentric nuclei estimated fibers percent value

Estimated percent of fibers in eccentric nuclei.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12238 Biopsy and autopsy epon embedded tissue abnormalities location type

Type of abnormality observed microscopically in epon-embedded tissue specimen

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12266 Biopsy and autopsy excessive intracellular lipid severity grade

Severe lipid storage pathology involves excess Oil Red O+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild lipid storage pathology is difficult to determine at the light microscopic level and may only be evident on Oil Red O stain or on electron microscopy.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12525 Biopsy and autopsy fiber abnormality type

Fiber type abnormalities on a muscle biopsy

Core Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12252 Biopsy and autopsy fiber size variation result type

Distribution of the atrophic fibers.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12249 Biopsy and Autopsy histochemical stains diagnostic abnormalities present type

The diagnostic abnormalities present on the histochenmical stains for the participant's/subject's tissue

Supplemental-Highly Recommended Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12269 Biopsy and autopsy immunohistochemical immunofluorescence assays performed

List of stains used

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12259 Biopsy and autopsy inflammation type

Perivascular inflammation is focused around blood vessels, whereas diffuse inflammation also spreads across the muscle tissue. Inflammatory cells identified include lymphocytes, neutrophils, macrophages, and eosinophils. At times, microorganisms can be identified and should be mentioned.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12261 Biopsy and autopsy inflammatory cell type

Type of inflammatory cells identified.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12267 Biopsy and autopsy liver biopsy autopsy results

The results of the liver biopsy

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12262 Biopsy and autopsy microorganisms name

Name of microorganisms identified in biopsy or autopsy specimen

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12276 Biopsy and autopsy mitochondria abnormality type

Type of mitochondria abnormality in muscle biopsy

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12254 Biopsy and autopsy myopathy-associated pathological structures type

The type of myopathy-associated pathological structures seen in the histology of the biopsy or autopsy specimen

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12257 Biopsy and autopsy nemaline rod type

Rod-shaped structures, visible at high magnification, which are most visible on Gomori trichrome stain and on EM preparations

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12528 Biopsy and autopsy nemaline rods restricted to one fiber text

Nemaline rods restricted to one fiber text

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12273 Biopsy and autopsy normal immunoreactivity assay name

Name of the normal immunoreactivity assay used

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C17904 Biopsy and autopsy pathological inclusions text

Text describing pathological inclusions (if any)

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12260 Biopsy and autopsy perivascular inflammation type

Evidence of vascular damage includes damaged vessels in association with perivascular inflammation and the presence of fibrin thrombi located within vascular spaces.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12529 Biopsy and autopsy ragged red fibers estimated count

Ragged red fibers estimated number

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12274 Biopsy and autopsy reduced immunoreactivity assay name

Reduced immunoreactivity that were noted on the immunohistochemical stains.

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12247 Biopsy and Autopsy tissue collection method type

The type of method used for collection of the tissue specimen

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12526 Biopsy and autopsy type 1 predominance fiber percentage value

Percentage of Type 1 predominance fiber present

Supplemental-Highly Recommended Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12527 Biopsy and autopsy type 2 predominance fiber percentage value

Percentage of Type 2 predominance fiber present

Supplemental-Highly Recommended Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
C12530 Biopsy autopsy COX-negative fibers estimated count

COX-negative fibers estimated number

Supplemental Muscle Biopsy and Autopsy Tissue Myotonic Muscular Dystrophy Myotonic Muscular Dystrophy
Displaying 51 - 75 of 736

The NINDS CDE Team does not post proprietary instruments/scales recommended by the CDE Working Groups on this website. This includes, but is not limited to, copyrighted or trademarked instruments/scales. Information about recommended instruments can be found in the Notice of Copyright (NOC) documents under ‘CRF Module/Guideline’ on each disorder’s data standards page. For any questions regarding these instruments/scales please contact the corresponding owner/author. The NINDS CDE Team is not responsible for the availability or content of these external sites, nor does the NINDS CDE Team endorse, warrant or guarantee the products, services or information described or offered at these other internet sites.