CDE Detailed Report
Disease: Huntington's Disease
Subdomain Name: Other Clinical Data
CRF: Neuropathology Data Form
Displaying 151 - 175 of 175
Subdomain Name: Other Clinical Data
CRF: Neuropathology Data Form
Displaying 151 - 175 of 175
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C15062 | Brain atrophy nucleus coeruleus Lewy body containing neurons and Lewy neurites severity result | BrAtNucCoerLeBodLeNeuSevReslt | Quantitative result of the severity of lewy-body containing neurons (LBCN) and lewy neurites (LN) in the nucleus coeruleus | Quantitative result of the severity of lewy-body containing neurons (LBCN) and lewy neurites (LN) in the nucleus coeruleu | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18741 | Other pathology ischemic vascular disease specify text | OthrPathlgyIschmcVasclrDisST | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | Other, specify | Alphanumeric |
If yes, specify other |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C14970 | Brain harvesting date and time | BrainHarvestingDateTime | Date and time, if known the brain was harvested | Date and time, if known the brain was harvested | Date of Harvesting; Time of Harvesting | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
ISO 8601 - http://www.iso.org/iso/iso_catalogue.htm | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
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| C15094 | Lacunes single or multiple description text | LacunesSingMultiDescriptTxt | The text description of the lacunes | The text description of the lacunes | Describe | Alphanumeric |
Answer for each vascular territory and event category |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15041 | Brain atrophy neuronal loss severity result | BrAtNeurLossSevReslt | Quantitative result of the severity of neuronal loss in each location of the caudate nucleus | Quantitative result of the severity of neuronal loss in each location of the caudate nucleus | Yes, neuronal loss | 0;1+/4+;2+/4+;3+/4+;4+/4+;NA | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available | Alphanumeric |
Answer for caudate nucleus, pontes griseum or gray matter caudo-lenticular bridges, putamen, and globus pallidus anatomic sites. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08155 | CSF postmortem indicator | CSFPstmortemInd | Indicator of whether banked postmortem cerebrospinal fluid (CSF) is accessible | Indicator of whether banked postmortem cerebrospinal fluid (CSF) is accessible | Is banked postmortem CSF available? | Yes;No | Yes;No | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15073 | Brain atrophy cerebellum cortical neuronal loss in associative layer indicator | BrAtCerebCortNeurLossAssocInd | Indicator of cortical neuronal loss in the associative layer (molecular) of the cerebellum | Indicator of cortical neuronal loss in the associative layer (molecular) of the cerebellum | Associative layer (molecular) | No, neuronal loss;Yes, neuronal loss | No, neuronal loss;Yes, neuronal loss | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14981 | Brain atrophy coronal sections hippocampal formation status | BrainAtrophyCorSecHipcamFrStat | Status of hippocampal formation atrophy of the coronal sections upon gross examination | Status of hippocampal formation atrophy of the coronal sections upon gross examinatio | Hippocampal formation atrophy | Absent;Present | Absent;Present | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15105 | Diagnosis concomitant main indicator | DiagnosConcomitantMainInd | Indicator of whether the participant/ subject been diagnosed with a concomitant disease | Indicator of whether the participant/ subject been diagnosed with a concomitant disease | CONCOMITANT MAIN DIAGNOSIS | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17754 | Microscopic examination brain text | MicroExamBrainTxt | Note regarding microscopic examination of blockage source | Note regarding microscopical examination of blockage source | Microscopical examination Note | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15052 | Brain atrophy cerebral white matter myelin loss severity result | BrAtCereWMMyelinLosSevReslt | Quantitative result of the cerebral white matter myelin loss | Quantitative result of the cerebral white matter myelin loss | Yes, myelin loss | 0;1+/4+;2+/4+;3+/4+;4+/4+ | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if "Yes, myelin loss" is answered for 'Cerebral white matter: myelin loss". This question is answered for each brain anatomic site. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08170 | Neuritic plaque density category | NeuriticPlaqDenstyCat | Density of neuritic plaques (plaques with argyrophilic dystrophic neurites with or without dense amyloid cores) | Density of neuritic plaques (plaques with argyrophilic dystrophic neurites with or without dense amyloid cores | Neuritic plaques (plaques with amyloid core surrounded by a halo with dystrophic neurites) | No plaques;Sparse plaques (Up to 2 per 100X field);Moderate plaques (Up to 6 per 100X field);Frequent plaques (>7 per 100X field);Not assessed;Unknown | No plaques;Sparse plaques (Up to 2 per 100X field);Moderate plaques (Up to 6 per 100X field);Frequent plaques (>7 per 100X field);Not assessed;Unknown | Alphanumeric |
Amyloid plaques |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15084 | Brain atrophy Braak and Braak neurofibrillary stage indicator | BrAtBraakBraakNeurofibStageInd | Indicator of whether neuronal tangles are present | Indicator of whether neuronal tangles are present | Braak & Braak Neurofibrillary Tangle Stage | Absent;Present;Not assessed;Not available | Absent;Present;Not assessed;Not available | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14992 | Brain atrophy striatum status cribrosus or lacunaris severity result | BrAtStrStatusCribLacunSevReslt | Quantitative result of the severity of atrophy located in the status cribrosus or lacunaris, or both | Quantitative result of the severity of atrophy located in the status cribrosus or lacunaris, or bot | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15031 | Brain atrophy hippocampal formation neuronal loss indicator | BrAtHippocampFormNeurLossInd | Indicator of neuronal loss in the hippocampal formation | Indicator of neuronal loss in the hippocampal formatio | Hippocampal formation Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C02411 | Laterality type | LatTyp | Laterality type relative to the anatomic site of the body examined or affected | Laterality type relative to the anatomic site of the body examined or affected | Bilateral;Left;Right;Unknown | Bilateral;Left;Right;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-08-28 16:08:00.453 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15063 | Brain atrophy nucleus coeruleus globosum neuronal tangles status | BrAtNucCoerGloNeurTanglesStat | Status of globosum neuronal tangles (GNT) in the nucleus coeruleus | Status of globosum neuronal tangles (GNT) in the nucleus coeruleu | Globosum neuronal tangles (GNT) | Absent;Present | Absent;Present | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18992 | Macroscopical examination fresh brain other text | MacroExamFreshBrainOTH | The free-text field related to 'Macroscopical examination fresh brain source' specifying other text. The part(s) of the fresh brain used for macroscopical examination | The free-text field related to 'Macroscopical examination fresh brain source' specifying other text. The part(s) of the fresh brain used for macroscopical examination | Other, specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C14971 | Macroscopical examination fresh brain source | MacroExamFreshBrainSource | The part(s) of the fresh brain used for macroscopical examination | The part(s) of the fresh brain used for macroscopical examination | Macroscopical examination Fresh | Whole brain;Left half brain;Right half brain;Not available;Other specify | Whole brain;Left half brain;Right half brain;Not available;Other specify | Alphanumeric |
Indicate the parts selected for evaluation |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15095 | Hemorrhages single or multiple event category | HemorrhageSingMultiEvntCat | Category of the hemorrhages | Category of the hemorrhages | Yes | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15042 | Brain atrophy fibrillary astrocytosis severity result | BrAtFibAstroSevReslt | Quantitative result of the severity of fibrillary astrocytosis in each location of the caudate nucleus | Quantitative result of the severity of fibrillary astrocytosis in each location of the caudate nucleus | Yes, neuronal loss | 0;1+/4+;2+/4+;3+/4+;4+/4+;NA | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available | Alphanumeric |
Answer for caudate nucleus, pontes griseum or gray matter caudo-lenticular bridges, putamen, and globus pallidus anatomic sites. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08156 | Specimen other postmortem indicator | SpecmnOtherPstmortemInd | Indicator whether other banked postmortem specimens (e.g., blood, spinal cord, nerve, muscle) exist | Indicator whether other banked postmortem specimens (e.g., blood, spinal cord, nerve, muscle) exist | Are other banked postmortem specimens available? (e.g. blood, spinal cord, nerve, muscle) | Yes;No | Yes;No | Alphanumeric |
If YES is answered then explain what other type(s) of postmortem samples exist |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15074 | Brain atrophy cerebellum cortical neuronal loss in associative layer severity result | BrAtCerCortNeurLosAsocSevReslt | Quantitative result of the severity of cortical neuronal loss in the associative layer of the cerebellum | Quantitative result of the severity of cortical neuronal loss in the associative layer of the cerebellum | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14982 | Brain atrophy coronal sections hippocampal formation severity result | BrAtCorSecHippFormSevReslt | Quantitative result of the severity of hippocampal formation atrophy in the coronal sections of the brain | Quantitative result of the severity of hippocampal formation atrophy in the coronal sections of the brain | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15106 | Clinicopathology diagnosis final type | ClinicopathDiagnosFinalTyp | The participant/subject's final clinicopathological diagnosis | The participant/subject's final clinicopathological diagnosis | Yes | Huntington's disease;Encephalopathy of hypoxic-ischemic type, acute;Alzheimer changes;Status cribrosus and lucanaris;There is no diagnostic abnormality recognized;Other, specify | Huntington's disease;Encephalopathy of hypoxic-ischemic type, acute;Alzheimer changes;Status cribrosus and lucanaris;There is no diagnostic abnormality recognized;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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