CDE Detailed Report
Disease: content
Subdomain Name: Other Clinical Data
CRF: welcome
Displaying 51 - 100 of 175
Subdomain Name: Other Clinical Data
CRF: welcome
Displaying 51 - 100 of 175
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C15076 | Brain atrophy cerebellum cortical neuronal loss in receptive layer severity result | BrAtCerCortNeuLosRecLaSevReslt | Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum | Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14984 | Brain atrophy coronal sections amygdala severity result | BrAtCorSecAmygdalaSevReslt | Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain | Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15108 | Diagnoses final clinicopathological severity scale | DiagnosFinClinicopathSevScale | Scale of the severity or intensity of the diagnosis | Scale of the severity or intensity of the diagnosis | Final Clinicopathological Diagnosis | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
Only answered if "Encephalopathy of hypoxic-ischemic type, acute", "Alzheimer changes", or "Status cribrosus and lacunaris" are answered for Final Clinicopathological diagnoses |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15044 | Brain atrophy thalamus neuronal loss severity result | BrAtThalamusNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the thalamus | Quantitative result of the severity of neuronal loss in the thalamus | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
This question is answered if "Yes, neuronal loss" is answered for 'Thalamus: neuronal loss" |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08158 | Brain weight measurement | BrainWgtMeasr | Weight of the participant's/subject's brain in grams | Weight of the participant's/subject's brain in grams | Brain weight-Part weighed | Numeric Values |
This value should be recorded in grams (g) for all brain tissue weighed |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
gram | |||||||||
| C08175 | Cortical microinfarct indicator | CortclMicroinfarcInd | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Are there single or multiple cortical microinfarcts (each, <1.5cm in greatest dimension, including "granular atrophy")? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Cortical microinfarcts are defined as |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15087 | Ischemic or hemorrhagic vascular territories name | IschHemVasclTerritoriesName | Name of the vascular territories where ischemic or hemorrhagic changes occur | Name of the vascular territories where ischemic or hemorrhagic changes occur | Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) | ACA;MCA;PCA;Combined | ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15023 | Brain atrophy striatum brainstem status | BrAtStriatumBrainstemStat | Status of brainstem atrophy in the striatum | Status of brainstem atrophy in the striatu | Brainstem atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
Kemper TL. Neuroanatomical and Neuropathological changes during aging and dementia, Second edn., Oxford University Press, New York, 1994, 3-67. Esiri MM and Morris JH. Practical approach to pathological diagnosis. In: Esiri MM, Lee VM-Y, Trojanowski JQ, eds. The neuropathology of dementia. First ed. Cambridge CB2 2RU, UK: Cambridge University Press; 2004:48-74. | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17757 | Striatum atrophy hypothalamus atrophy status | StrAtrophyHypothAtrophyStat | Status of atrophy in the hypothalamus | Status of atrophy in the hypothalamu | Hypothalamus atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17766 | Striatum atrophy hydrocephalus third ventricle severity result | StrAtrophyHydroThVentSevReslt | Quantitative result of the severity of hydrocephalus located in the third ventricle | Quantitative result of the severity of hydrocephalus located in the third ventricl | Third ventricle | None;Mild;Moderate;Severe;Not assessed;Not available | None;Mild;Moderate;Severe;Not assessed;Not available | Alphanumeric |
Striatum atrophy; Hydrocephalus |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15055 | Brain atrophy substantia nigra pars reticulata neuronal loss indicator | BrAtSubNiParsReticNeurLosInd | Indicator of neuronal loss in the pars reticulata of the substantia nigra | Indicator of neuronal loss in the pars reticulata of the substantia nigr | Pars reticulata Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14974 | Brain atrophy surface status | BrainAtrophySurfStat | Status of cerebral atrophy on external surface of the brain upon gross examination | Status of cerebral atrophy on external surface of the brain upon gross examination | On gross examination of the external surface of the brain, cerebral atrophy | Absent;Present | Absent;Present | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15098 | Cortical laminar necrosis single or multiple event category | CortLaminNecSingMultiEvntCat | Category of the cortical laminar necrosis | Category of the cortical laminar necrosis | Yes | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15034 | Brain atrophy amygdala neuronal loss severity result | BrAtAmygdalaNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the amygdala | Quantitative result of the severity of neuronal loss in the amygdal | Yes, neuronal loss | 1+/4+;2+/4+;3+/4+;4+/4+ | 1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if 'Yes, neuronal loss' is answered for 'Amygdala neuronal loss' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08147 | Data source | DataSource | Source of the data provided on the case report form | Source of the data provided on the case report form | DATA SOURCE | Participant/subject;Mother;Father;Sister;Brother;Son;Daughter;Family, specify relation;Friend;Physician;Chart/Medical record;Other, specify;Unknown;Spouse | Participant/subject;Mother;Father;Sister;Brother;Son;Daughter;Family, specify relation;Friend;Physician;Chart/Medical record;Other, specify;Unknown;Spouse | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C18997 | Clinicopathology diagnosis final other text | ClinicopathDiagnosFinalOTH | the free-text related to 'Clinicopathology diagnosis final type' specifying other text. The participant/subject's final clinicopathological diagnosis | the free-text related to 'Clinicopathology diagnosis final type' specifying other text. The participant/subject's final clinicopathological diagnosis | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C15066 | Brain atrophy pons neuronal loss severity result | BrAtPonsNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the pons | Quantitative result of the severity of neuronal loss in the pons | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Pons: Neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15077 | Brain atrophy cerebellum cortical neuronal loss in effective layer indicator | BrAtCerebCortNeurLossEffLayInd | Indicator of cortical neuronal loss in the effective layer (Purkinje cells) of the cerebellum | Indicator of cortical neuronal loss in the effective layer (Purkinje cells) of the cerebellum | Effective layer (Purknje cells) | No, neuronal loss;Yes, neuronal loss | No, neuronal loss;Yes, neuronal loss | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14985 | Brain atrophy striatum status | BrAtStriatumStat | Status of striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Status of striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum (caudate nucleus [CN], putamen, globus pallidus, and nucleus accumbens) atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15109 | Abnormality no diagnosis type | AbnrmlyNoDiagTyp | The diagnosis if there is no abnormality recognized | The diagnosis if there is no abnormality recognized | There is no diagnostic abnormality recognized | Control brain;Huntington disease, grade 0 | Control brain=If without neurological and psychiatric troubles, and without HD-IT15 CAG repeat expansion;Huntington disease, grade 0=If without neurological and psychiatric troubles, but with HD-IT15 CAG repeat expansion | Alphanumeric |
This question is answered only if "There is no diagnostic abnormality recognized" is answered for Final clinicopathological diagnosis. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15045 | Brain atrophy thalamus neuronal loss nuclei name | BrAtThalamusNeurLossNucName | Name of the nuclei in the thalamus involved in the neuronal loss | Name of the nuclei in the thalamus involved in the neuronal loss | If Yes, specify nuclei that are mainly involved | Motor nuclei ventral anterior;Motor nuclei ventral lateral;Centrum medianum;Limbic nuclei anterior;Limbic nuclei dorso-median;Other, specify | Motor nuclei ventral anterior;Motor nuclei ventral lateral;Centrum medianum;Limbic nuclei anterior;Limbic nuclei dorso-median;Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C08160 | Brain tissue weigh type | BrainTissWeighedTyp | Type of brain tissue weighed | Type of brain tissue weighed | Brain weight-Part weighed | Fresh whole brain;Fixed whole brain;Fixed not available;Other;Fixed left half;Fixed right half;Fresh left half;Fresh not available;Fresh right half | Fresh whole brain;Fixed whole brain;Fixed not available;Other;Fixed left half;Fixed right half;Fresh left half;Fresh not available;Fresh right half | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08176 | Lacunes single or multiple indicator | LacunesSingMultiInd | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels, most often in basal ganglia, thalamus, pons, cerebellum and cerebral white matter | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels, most often in basal ganglia, thalamus, pons, cerebellum and cerebral white matte | Are there single or multiple lacunes (each > 1,5cm, but = 2c, small artery infarcts | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Lacunes are defined as > 1.5cm each but = 2 cm small artery infarcts. |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15088 | Ischemic or hemorrhagic changes description text | IschHemChangesDescriptTxt | The text description of the ischemic or hemorrhagic changes | The text description of the ischemic or hemorrhagic changes | Describe | Alphanumeric |
Answer for each vascular territory and event category |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15024 | Brain atrophy striatum brainstem severity result | BrAtStriatBrainstemSevReslt | Quantitative result of the severity of brainstem atrophy located in the striatum | Quantitative result of the severity of brainstem atrophy located in the striatu | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
This question is answered if 'Present' is answered for 'Brainstem atrophy' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17758 | Striatum atrophy hypothalamus atrophy severity result | StrAtrophyHypoAtrophySevReslt | Quantitative result of the severity of atrophy located in the hypothalamus | Quantitative result of the severity of atrophy located in the hypothalam | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17767 | Striatum atrophy hydrocephalus fourth ventricle severity result | StrAtrophyHydroFoVentSevReslt | Quantitative result of the severity of hydrocephalus located in the fourth ventricle | Quantitative result of the severity of hydrocephalus located in the fourth ventricl | Fourth ventricle | None;Mild;Moderate;Severe;Not assessed;Not available | None;Mild;Moderate;Severe;Not assessed;Not available | Alphanumeric |
Striatum atrophy; Hydrocephalus |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15056 | Brain atrophy substantia nigra pars reticulata neuronal loss severity result | BrAtSubNiParsRetNeuLosSevReslt | Quantitative result of the severity of neuronal loss in the pars reticulata | Quantitative result of the severity of neuronal loss in the pars reticulat | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14975 | Brain lobe examination anatomic site | BrainLobeAExamAntmicSite | Anatomic site examined in the brain | Anatomic site examined in the brain | If yes | Frontal;Parietal;Temporal;Occipital | Frontal;Parietal;Temporal;Occipital | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15099 | Cortical laminar necrosis single or multiple vascular territories name | CortLaNecSingMultiVasTerName | Name of the vascular territories where cortical laminar necrosis occurs | Name of the vascular territories where cortical laminar necrosis occurs | Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) | ACA;MCA;PCA;Combined | ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15035 | Brain atrophy neuronal loss fibrillary astrocytosis caudate nucleus anatomic site | BrAtNeLosFibAstCauNuAntmicSite | Anatomic site in the caudate nucleus (CN) where neuronal loss and/or fibrillary astrocytosis is/are present | Anatomic site in the caudate nucleus (CN) where neuronal loss and/or fibrillary astrocytosis is/are present | Is there evidence of neuronal loss and fibrillary astrocytosis? (caudate nucleus[CN], putamen, globus pallidus and nucleus accumbens | Head, rostral, medial half;Head, rostral, lateral half;Head, caudal;Body;Tail | Head, rostral, medial half;Head, rostral, lateral half;Head, caudal;Body;Tail | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08148 | Neuropath specimen identifier number | NeuropthSpecmnIDNum | Unique identification number given to the neuropathology specimen | Unique identification number given to the neuropathology specimen | Neuropath ID | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15067 | Brain atrophy pontine nuclei globosum neuronal tangles status | BrAtPontineNucGloNeurTanStat | Status of globosum neuronal tangles (GNT) in the pontine nuclei | Status of globosum neuronal tangles (GNT) in the pontine nucle | Pontine nuclei Globosum neuronal tangles (GNT) | Absent;Present | Absent;Present | Alphanumeric |
Pons: Neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15078 | Brain atrophy cerebellum cortical neuronal loss in effective layer severity result | BrAtCerCortNeuLosEffLaSevReslt | Quantitative result of the severity of cortical neuronal loss in the effective layer of the cerebellum | Quantitative result of the severity of cortical neuronal loss in the effective layer of the cerebellum | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14986 | Brain atrophy striatum head of caudate nucleus severity result | BrAtStrCauNucHeadSevReslt | Quantitative result of the severity of atrophy located in the head of the caudate nucleus (CN) (at the level where the anterior limb of the internal capsule [ALIC] joins with the basal white matter). | Quantitative result of the severity of atrophy located in the head of the caudate nucleus (CN) (at the level where the anterior limb of the internal capsule [ALIC] joins with the basal white matter). | Head of the CN | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Striatum atrophy: At the level where the anterior limb of the internal capsule (ALIC) joins with the basal white matter:atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15110 | Atherosclerotic luminal stenosis percentage range | AtheroLuminStenPercentRange | Range for the estimated luminal stenosis percentage if stenotic vascular changes (of the circle of Willis) | Range for the estimated luminal stenosis percentage if stenotic vascular changes (of the circle of Willis) | Yes, stentoic | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+=up to 30% stenosis;Moderate 2+=up to 50% stenosis;Severe 3+=up to 8-% stenosis;Very severe 4+=apparent occlusion | Alphanumeric |
This question is answered only if "Yes stenotic" is answered for "Are there atherosclerotic, either non-stenotic or stenotic vascular changes (of the circle of Willis)?" |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15046 | Brain atrophy thalamus neuronal loss nuclei severity result | BrAtThalamusNeurLosNucSevReslt | Quantitative result of the severity of neuronal loss in thalamic nuclei | Quantitative result of the severity of neuronal loss in thalamic nuclei | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
To be answered for each nuclei name |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08162 | National Institute on Aging (NIA) or Reagan Institute neuropathological criteria scale | NIAReaganInNeuropathCritScale | National Institute on Aging (NIA)/Reagan Institute neuropathological criteria used to determine the likelihood of dementia being due to Alzheimer's disease. | National Institute on Aging (NIA)/Reagan Institute neuropathological criteria used to determine the likelihood of dementia being due to Alzheimer's disease. | NIA/Reagan Institute neuropathological criteria likelihood of dementia being due to Alzheimer disease (AD) | Low likelihood of dementia being due to Alzheimer's disease;Intermediate likelihood of dementia being due to Alzheimer's disease;High likelihood of dementia being due to Alzheimer's disease;Criteria not met;Not assessed;Not available | Low likelihood of dementia being due to Alzheimer's disease;Intermediate likelihood of dementia being due to Alzheimer's disease;High likelihood of dementia being due to Alzheimer's disease;Criteria not met;Not assessed;Not available | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08177 | Hemorrhage indicator | HemrrhgInd | Indicator of the presence of cerebral hemorrhages, regardless of size in any region of the brain | Indicator of the presence of cerebral hemorrhages, regardless of size in any region of the brain | Are there single or multiple hemorrhages? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15089 | Cortical infarcts single or multiple event category | CorInfarcSingMultiEventCat | Category of the cortical microinfarcts | Category of the cortical microinfarcts | If yes | Single;Multiple | Single;Multiple | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15025 | Brain atrophy striatum cerebellum status | BrAtStriatumCerebellumStat | Status of cerebellum atrophy in the striatum | Status of cerebellum atrophy in the striatu | Cerebellum atrophy | Absent;Present | Absent;Present | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17759 | Striatum atrophy thalamus atrophy status | StrAtrophyThalamusAtrophyStat | Status of atrophy in the thalamus | Status of atrophy in the thalamu | Thalamus atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18153 | Data unknown text | DataUnknwnTxt | The free-text field to Mark an "X" in to record if data are unknown or not available | The free-text field to Mark an "X" in to record if data are unknown or not availabl | CAG repeat HD-IT 15 CAG repeat expansion unknown | Alphanumeric |
If the size of the HD-IT 15 CAG expansion is unknown, record as Not Known in the next data element. |
Adult;Pediatric | Supplemental | 3.00 | 2013-07-17 09:26:36.973 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 20 |
Free-Form Entry |
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| C15057 | Brain atrophy substantia nigra Lewy body containing neurons and Lewy neurites status | BrAtSubNigraLeBodyLeNeurStat | Status of lewy-body containing neurons (LBCN) and lewy neurites (LN) in the substantia nigra | Status of lewy-body containing neurons (LBCN) and lewy neurites (LN) in the substantia nigr | Lewy body containing neurons (LBCN) and Lewy neurites (LN) | Absent;Present | Absent;Present | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14976 | Brain atrophy surface severity result | BrainAtrophySurfSevReslt | Quantitative result of the severity of cerebral atrophy on external brain surface | Quantitative result of the severity of cerebral atrophy on external brain surface | Present | 0;1+/4+;2+/4+;3+/4+;4+/4+ | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
This question is answered if "Present" is answered for "On gross examination of the external surface of the brain, cerebral atrophy". This question is answered for each of the brain anatomic sites. |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15100 | Cortical laminar necrosis single or multiple text | CortLaminarNecSingMultiTxt | The text description of the cortical laminar necrosis | The text description of the cortical laminar necrosis | Describe | Alphanumeric |
Answer for each vascular territory and event category |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15036 | Brain atrophy neuronal loss and fibrillary astrocytosis pontes griseum or gray matter caudo-lenticular bridges anatomic site | BrAtNeLosFibAstroPonAntmicSite | Anatomic site in the pontes griseum or gray matter caudo-lenticular bridges where neuronal loss and/or fibrillary astrocytosis is/are present | Anatomic site in the pontes griseum or gray matter caudo-lenticular bridges where neuronal loss and/or fibrillary astrocytosis is/are present | Pontes griseum or gray matter caudo-lenticular bridges | Dorsal half;Ventral half | Dorsal half;Ventral half | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08149 | Diagnosis final clinical death type | DiagnosFinalClinDeathTyp | Physician's final clinical diagnosis for the participant/subject | Physician's final clinical diagnosis for the participant/subject | FINAL CLINICAL DIAGNOSIS BEFORE DETAH | Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Other, specify;Chorea gravidarum;Dentato-rubro-pallido-luysian atrophy (DRPLA), with genetically confirmed expansion of CAG repeats;Dentato-rubro-pallido-luysian atrophy (DRPLA), without genetically confirmed expansion of CAG repeats;Fragile X syndrome with genetically confirmed expansion of CGG repeats;Fragile X syndrome without genetically confirmed expansion of CGG repeats;Friedreich ataxia with genetically confirmed expansion of GAA repeats;Friedreich ataxia without genetically confirmed expansion of GAA repeats;Frontotemporal lobar degeneration;Hepatolenticular degeneration or Wilson disease;Huntington disease with genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease without genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease-like 2 genetically confirmed expansion of trinucleotide repeats;Huntington disease-like without genetically confirmed expansion of trinucleotide repeats;Kennedy disease with genetically confirmed expansion of CAG repeats;Kennedy disease without genetically confirmed expansion of CAG repeats;Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome);Senile chorea or vascular chorea;Spinocerebellar ataxia with genetically confirmed expansion of either CAG or CTG repeats;Spinocerebellar ataxia without genetically confirmed expansion of either CAG or CTG repeats;Subacute sclerosing panencephalitis;Sydenham chorea;Tardive dyskinesia;Neuroacanthocytosis;Pick disease | Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Other, specify;Chorea gravidarum;Dentato-rubro-pallido-luysian atrophy (DRPLA), with genetically confirmed expansion of CAG repeats;Dentato-rubro-pallido-luysian atrophy (DRPLA), without genetically confirmed expansion of CAG repeats;Fragile X syndrome with genetically confirmed expansion of CGG repeats;Fragile X syndrome without genetically confirmed expansion of CGG repeats;Friedreich ataxia with genetically confirmed expansion of GAA repeats;Friedreich ataxia without genetically confirmed expansion of GAA repeats;Frontotemporal lobar degeneration;Hepatolenticular degeneration or Wilson disease;Huntington disease with genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease without genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease-like 2 genetically confirmed expansion of trinucleotide repeats;Huntington disease-like without genetically confirmed expansion of trinucleotide repeats;Kennedy disease with genetically confirmed expansion of CAG repeats;Kennedy disease without genetically confirmed expansion of CAG repeats;Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome);Senile chorea or vascular chorea;Spinocerebellar ataxia with genetically confirmed expansion of either CAG or CTG repeats;Spinocerebellar ataxia without genetically confirmed expansion of either CAG or CTG repeats;Subacute sclerosing panencephalitis;Sydenham chorea;Tardive dyskinesia;Neuroacanthocytosis;Pick disease | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C15068 | Brain atrophy pontine nuclei globosum neuronal tangles (GNT) severity result | BrAtPontNucGloNeurTanSevReslt | Quantitative result of the severity of globosum neuronal tangles in the pontine nuclei | Quantitative result of the severity of globosum neuronal tangles in the pontine nucle | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Pons: Neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15079 | Brain atrophy cerebellum cortical neuronal loss in bergman gliosis status | BrAtCerebCortNeurLosBerGliStat | Status of cortical neuronal loss in the Bergman gliosis (BG) of the cerebellum | Status of cortical neuronal loss in the Bergman gliosis (BG) of the cerebellum | Bergman gliosis | Absent;Present | Absent;Present | Alphanumeric |
Cerebellum; Cortical neuronal loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
