CDE Detailed Report

Disease: Parkinson's Disease
Sub-Domain: Motor Function
CRF: Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS)

Displaying 1 - 50 of 83
CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C09980 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - hobby other activity score MDSUPDRSHobbieOthrActScore Score for the participant's/subject's ability to perform hobbies or other activities, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to perform hobbies or other activities, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) DOING HOBBIES AND OTHER ACTIVITES 0;1;2;3;4 Normal: Not at all (no problems);Slight: I am a bit slow but do these activities easily;Mild: I have some difficulty doing these activities;Moderate: I have major problems doing these activities, but still do most;Severe: I am unable to do most or all of these activities Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10012 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - global spontaneity of movement score MDSUPDRSGlblSpontntyMvmntScore Score for the participant's/subject's level of global spontaneity of movement observing the slowness, hesitancy, and small amplitude and poverty of movement in general Score for the participant's/subject's level of global spontaneity of movement observing the slowness, hesitancy, and small amplitude and poverty of movement in general GLOBAL SPONTANEITY OF MOVEMENT (BODY BRADYKINESIA) 0;1;2;3;4 Normal: No problems;Slight: Slight global slowness and poverty of spontaneous movements;Mild: Mild global slowness and poverty of spontaneous movements;Moderate: Moderate global slowness and poverty of spontaneous movements;Severe: Severe global slowness and poverty of spontaneous movements. Numeric Values

This assessment is based on the examiner's global impression after observing for spontaneous gestures while sitting, and the nature of arising and walking.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09991 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - facial expression score MDSUPDRSFacialExprScore Score for the participant's/subject's ability to make facial expressions observing the eye-blink frequency, masked faces or loss of facial expression, spontaneous smiling and parting of lips, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to make facial expressions, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) FACIAL EXPRESSION 0;1;2;3;4 Normal: Normal facial expression;Slight: Minimal masked faces manifested only by decreased frequency of blinking;Mild: In addition to decreased eye-blink frequency, Masked faces present in the lower face as well, namely fewer movements around the mouth, such as less spontaneous smiling, but lips not parted;Moderate: Masked faces with lips parted some of the time when the mouth is at rest;Severe: Masked faces with lips parted most of the time when the mouth is at rest Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10023 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - dyskinesia chorea or dystonia presence score MDSUPDRSDyskChreaDystnaPrsScr Indicator for whether the participant's/subject's had any dyskinesia (chorea or dystonia) present during examination, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Indicator for whether the participant's/subject's had any dyskinesia (chorea or dystonia) present during examination, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Were dyskinesias (chorea or dystonia) present during examination? No;Yes No;Yes Alphanumeric

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09959 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - recent cognitive impairment score MDSUPDRSRcntCogImprmntScore Score for the participant's/subject's cognitive impairment including the cognitive slowing, impaired reasoning, memory loss, deficits in attention and orientation and how it impacts the activities of daily living, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's cognitive impairment including the cognitive slowing, impaired reasoning, memory loss, deficits in attention and orientation and how it impacts the activities of daily living, as a part of Movement Disorder Society - COGNITIVE IMPAIRMENT 0;1;2;3;4 Normal: No cognitive impairment;Slight: Impairment appreciated by patient or caregiver with no concrete interference with the patient's ability to carry out normal activities and social interactions;Mild: Clinically evident cognitive dysfunction, but only minimal interference with the patient's ability to carry out normal activities and social interactions;Moderate: Cognitive deficits interfere with but do not preclude the patient's ability to carry out normal activities and social interactions;Severe: Cognitive dysfunction precludes the patient's ability to carry out normal activities and social interactions. Numeric Values

Instructions to examiner: Consider all types of altered level of cognitive function including cognitive slowing, impaired reasoning, memory loss, deficits in attention and orientation. Rate their impact on activities of daily living as perceived by the patient and/or caregiver. Instructions to patients [and caregiver]: Over the past week have you had problems remembering things, following conversations, paying attention, thinking clearly, or finding your way around the house or in town? [If yes, examiner asks patient or caregiver to elaborate and probes for information]

URL: http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09970 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - constipation problem score MDSUPDRSConstipProbScore Score for the participant's/subject's level of constipation, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of constipation, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) CONSTIPATION PROBLEMS 0;1;2;3;4 Normal: No constipation;Slight: I have been constipated. I use extra effort to move my bowels. However, this problem does not disturb my activities or my being comfortable;Mild: Constipation causes me to have some troubles doing things or being comfortable;Moderate: Constipation causes me to have a lot of trouble doing things or being comfortable. However, it does not stop me from doing anything;Severe: I usually need physical help from someone else to empty my bowels. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10002 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - pronation supination left hand movement score PronatSupinLftHndMvmntScore Score for the participant's/subject's ability to pronate and supinate the left hand evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to pronate and supinate the left hand evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) PRONATION SUPINATION MOVEMENTS OF HANDS 0;1;2;3;4 Normal: No problems;Slight: Any of the following: a) the regular rhythm is broken with one or two interruptions or hesitations of the movement| b) slight slowing| c) the amplitude decrements near the end of the sequence;Mild: Any of the following: a) 3 to 5 interruptions during the movements, b) mild slowing, c) the amplitude decrements midway in the sequence;Moderate: Any of the following: a) more than 5 interruptions during the movement or at least one longer arrest (freeze) in ongoing movement, b) moderate slowing c) the amplitude decrements starting after the 1st supination-pronation sequence;Severe: Cannot or can only barely perform the task because of slowing, interruptions or decrements Numeric Values

Test each hand separately. Demonstrate the task, but do not continue to perform the task while the patient is being tested. Rate each side separately, evaluating speed, amplitude, hesitations, halts and decrementing amplitude.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10034 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - percent off value MDSUPDRSPrcntOffVal Value of the percent of time the participant/subject is OFF, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Value of the percent of time the participant/subject is OFF, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Percent OFF equals two over one times one hundred Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Free-Form Entry

C09981 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - turn bed score MDSUPDRSTurngBedScore Score for the participant's/subject's ability to turn in bed, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to turn in bed, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Turning in bed and adjusting bed clothes 0;1;2;3;4 Normal: Not at all (no problems);Slight: I have a bit of trouble turning, but I do not need any help;Mild I have a lot of trouble turning and need occasional help from someone else;Moderate: To turn over I often need help from someone else;Severe: I am unable to turn over without help from someone else Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10013 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - postural tremor right hand score MDSUPDRSPostrlTremorRtHndScore Score for the participant's/subject's level of postural tremor of the right hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of postural tremor of the right hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) POSTURAL TREMOR OF THE HANDS 0;1;2;3;4 Normal: No tremor;Slight: Tremor is present but less than 1 cm in amplitude;Mild: Tremor is at least 1 but less than 3 cm in amplitude;Moderate: Tremor is at least 3 but less than 10 cm in amplitude;Severe: Tremor is at least 10 cm in amplitude Numeric Values

Rate each hand separately. Rate the highest amplitude seen. Instruct the patient to stretch the arms out in front of the body with palms down. The wrist should be straight and the fingers comfortably separated so that they do not touch each other. Observe this posture for 10 seconds.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09960 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - hallucination psychosis score MDSUPDRSHallucPsychosScore Score of the participant's/subject's hallucination and psychosis considering both illusions and hallucinations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score of the participant's/subject's hallucination and psychosis considering both illusions and hallucinations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) HALLUCINATIONS AND PSYCHOSIS 0;1;2;3;4 Normal: No hallucinations or psychotic behavior;Slight: Illusions or non-formed hallucinations, but patient recognizes them without loss of insight;Mild: Formed hallucinations independent of environmental stimuli. No loss of insight;Moderate: Formed hallucinations with loss of insight;Severe: Patient has delusions or paranoia. Numeric Values

Instructions to examiner: Consider both illusions (misinterpretations of real stimuli) and hallucinations (spontaneous false sensations). Consider all major sensory domains (visual, auditory, tactile, olfactory and gustatory). Determine presence of unformed (for example sense of presence or fleeting false impressions) as well as formed (fully developed and detailed) sensations. Rate the patients insight into hallucinations and identify delusions and psychotic thinking. Instructions to patients [and caregiver]: Over the past week have you seen, heard, smelled or felt things that were not really there? [If yes, examiner asks patient or caregiver to elaborate and probes for information]

URL: http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09992 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - neck rigidity score MDSUPDRSNeckRigidScore Score for the participant's/subject's neck rigidity , as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's neck rigidity , as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) RIGIDTY 0;1;2;3;4 Normal: No rigidity;Slight: Rigidity only detected with activation maneuver;Mild: Rigidity detected without the activation maneuver, but full range of motion is easily achieved;Moderate: Rigidity detected without the activation maneuver| full range of motion is achieved with effort;Severe: Rigidity detected without the activation maneuver and full range of motion not achieved. Numeric Values

First, test without an activation maneuver. Test and rate neck and each limb separately. For arms, test the wrist and elbow joints simultaneously. For legs, test the hip and knee joints simultaneously. If no rigidity is detected, use an activation maneuver such as tapping fingers, fist opening/closing, or heel tapping in a limb not being tested. Explain to the patient to go as limp as possible as you test for rigidity.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10024 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - movement interference score MDSUPDRSMvmntIntrfrnceScore Indicator for whether the participant's/subject's movements interfered with the ratings because of the dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Indicator for whether the participant's/subject's movements interfered with the ratings because of the dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) If yes, did these movements interfere with your ratings? No;Yes No;Yes Alphanumeric

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09971 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - light headedness on stand score MDSUPDRSLiteHeadStndngScore Score for the participant's/subject's level of light headedness when standing, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of light headedness when standing, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) LIGHT HEADEDNESS ON STANDING 0;1;2;3;4 Normal: No dizzy or foggy feelings;Slight: Dizzy or foggy feelings occur. However, they do not cause me troubles doing things;Mild: Dizzy or foggy feelings cause me to hold on to something, but I do not need to sit or lie back down;Moderate: Dizzy or foggy feelings cause me to sit or lie down to avoid fainting or falling;Severe: Dizzy or foggy feelings cause me to fall or faint. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10003 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - right foot toe tap score RteFtToeTppngScore Score for the participant's/subject's ability to tap the right foot toes evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to tap the right foot toes evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) TOE TAPPING 0;1;2;3;4 Normal: No problem;Slight: Any of the following: a) the regular rhythm is broken with one or two interruptions, or hesitations of the tapping movement, b) slight slowing| c) amplitude decrements near the end of the ten taps;Mild: Any of the following: a) 3 to 5 interruptions during the tapping movements, b) mild slowing, c) amplitude decrements midway in the task;Moderate: Any of the following: a) more than 5 interruptions during the tapping movements or at least one longer arrest (freeze) in ongoing movement, b) moderate slowing, c) amplitude decrements after the first tap;Severe: Cannot or can only barely perform the task because of slowing, interruptions or decrements Numeric Values

Have the patient sit in a straight-backed chair with arms, both feet on the floor. Test each foot separately. Demonstrate the task, but do not continue to perform the task while the patient is being tested. Rate each side separately, evaluating speed, amplitude, hesitations, halts and decrementing amplitude.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10035 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - impact fluctuation score MDSUPDRSFuncImpactFluctScore Score for the participant's/subject's level of functional impact of fluctuations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of functional impact of fluctuations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) FUNCTIONAL IMPACT OF FLUCTUATIONS 0;1;2;3;4 Normal: No fluctuations or No impact by fluctuations on performance of activities or social interactions;Slight: Fluctuations impact on a few activities, but during OFF, the patient usually performs all activities and participates in all social interactions that typically occur during the ON state;Mild: Fluctuations impact many activities, but during OFF, the patient still usually performs all activities and participates in all social interactions that typically occur during the ON state;Moderate: Fluctuations impact on the performance of activities during OFF to the point that the patient usually does not perform some activities or participate in some social interactions that are performed during ON periods;Severe: Fluctuations impact on function to the point that, during OFF, the patient usually does not perform most activities or participate in most social interactions that are performed during ON periods Numeric Values

Determine the degree to which motor fluctuations impact on the patient's daily function in terms of activities and social interactions. This question concentrates on the difference between the ON state and the OFF state. If the patient has no OFF time, the rating must be 0, but if patients have very mild fluctuations, it is still possible to be rated 0 on this item if no impact on activities occurs. Refer to instrument for additional instructions.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09982 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - tremor score MDSUPDRSTremorScore Score for the participant's/subject's level of shaking or tremor, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of shaking or tremor, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) TREMOR 0;1;2;3;4 Normal: Not at all. I have no shaking or tremor;Slight: Shaking or tremor occurs but does not cause problems with any activities;Mild: Shaking or tremor causes problems with only a few activities;Moderate: Shaking or tremor causes problems with many of my daily activities;Severe: Shaking or tremor causes problems with most or all activities Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10014 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - postural tremor left hand score MDSUPDRSPostrlTremrLftHndScore Score for the participant's/subject's level of postural tremor of the left hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of postural tremor of the left hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) POSTURAL TREMOR OF THE HANDS 0;1;2;3;4 Normal: No tremor;Slight: Tremor is present but less than 1 cm in amplitude;Mild: Tremor is at least 1 but less than 3 cm in amplitude;Moderate: Tremor is at least 3 but less than 10 cm in amplitude;Severe: Tremor is at least 10 cm in amplitude Numeric Values

Rate each hand separately. Rate the highest amplitude seen. Instruct the patient to stretch the arms out in front of the body with palms down. The wrist should be straight and the fingers comfortably separated so that they do not touch each other. Observe this posture for 10 seconds.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09961 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - depress mood score MDSUPDRSDrpssMoodScore Score of the participant's/subject's depressed mood considering low mood, sadness, hopelessness, feelings of emptiness or loss of enjoyment, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score of the participant's/subject's depressed mood considering low mood, sadness, hopelessness, feelings of emptiness or loss of enjoyment, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) DEPRESSED MOOD 0;1;2;3;4 0= Normal: No depressed mood;Slight: Episodes of depressed mood that are not sustained for more than one day at a time. No interference with patient's ability to carry out normal activities;Mild: Depressed mood that is sustained over days, but without interference with normal activities and social interactions.;Moderate: Depressed mood that interferes with, but does not preclude, the patient's ability to carry out normal activities and social interactions.;Severe: Depressed mood precludes patient's ability to carry out normal activities and social interactions. Numeric Values

Instructions to examiner: Consider low mood, sadness, hopelessness, feelings of emptiness or loss of enjoyment. Determine their presence and duration over the past week and rate their interference with the patient's ability to carry out daily routines and engage in social interactions. Instruction to the patient (and caregiver): Over the past week have you felt low, sad, hopeless or unable to enjoy things? If yes, was this feeling for longer than one day at a time? Did it make it difficult for you carry out your usual activities or to be with people? If yes, examiner asks patient or caregiver to elaborate and probes for information]

URL: http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09993 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - right upper extremity rigid score MDSUPDRSRUERigidScore Score for the participant's/subject's right upper extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's right upper extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) RIGIDTY 0;1;2;3;4 Normal: No rigidity;Slight: Rigidity only detected with activation maneuver;Mild: Rigidity detected without the activation maneuver, but full range of motion is easily achieved;Moderate: Rigidity detected without the activation maneuver| full range of motion is achieved with effort;Severe: Rigidity detected without the activation maneuver and full range of motion not achieved. Numeric Values

First, test without an activation maneuver. Test and rate neck and each limb separately. For arms, test the wrist and elbow joints simultaneously. For legs, test the hip and knee joints simultaneously. If no rigidity is detected, use an activation maneuver such as tapping fingers, fist opening/closing, or heel tapping in a limb not being tested. Explain to the patient to go as limp as possible as you test for rigidity.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10025 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - Hoehn and Yahr stage score MDSUPDRSHoehnYahrStageScore Score for the participant's/subject's symptoms progression on the Hoehn and Yahr stage scale, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's symptoms progression on the Hoehn and Yahr stage scale, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) HOEHN AND YAHR STAGE 0;1;2;3;4;5 Asymptomatic;Unilateral involvement only;Bilateral involvement without impairment of balance;Mild to moderate involvement, some postural instability but physically independent, needs assistance to recover from pull test;Severe disability, still able to walk or stand unassisted;Wheelchair bound or bedridden unless aided Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09972 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - fatigue score MDSUPDRSFatigueScore Score for the participant's/subject's level of fatigue, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of fatigue, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) FATIGUE 0;1;2;3;4 Normal: No fatigue;Slight: Fatigue occurs. However it does not cause me troubles doing things or being with people;Mild: Fatigue causes me some troubles doing things or being with people;Moderate: Fatigue causes me a lot of troubles doing things or being with people. However, it does not stop me from doing anything;Severe: Fatigue stops me from doing things or being with people. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10004 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - left foot toe tap score MDSUPDRSLftFtToeTppngScore Score for the participant's/subject's ability to tap the left foot toes evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to tap the left foot toes evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) TOE TAPPING 0;1;2;3;4 Normal: No problem;Slight: Any of the following: a) the regular rhythm is broken with one or two interruptions, or hesitations of the tapping movement, b) slight slowing| c) amplitude decrements near the end of the ten taps;Mild: Any of the following: a) 3 to 5 interruptions during the tapping movements, b) mild slowing, c) amplitude decrements midway in the task;Moderate: Any of the following: a) more than 5 interruptions during the tapping movements or at least one longer arrest (freeze) in ongoing movement, b) moderate slowing, c) amplitude decrements after the first tap;Severe: Cannot or can only barely perform the task because of slowing, interruptions or decrements Numeric Values

Have the patient sit in a straight-backed chair with arms, both feet on the floor. Test each foot separately. Demonstrate the task, but do not continue to perform the task while the patient is being tested. Rate each side separately, evaluating speed, amplitude, hesitations, halts and decrementing amplitude.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10036 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - complexity motor fluctuation score MDSUPDRSComplxtyMtrFluctScore Score for the participant's/subject's level of complex motor fluctuations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of complex motor fluctuations, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) COMPLEXITY OF MOTOR FLUCTUATIONS 0;1;2;3;4 Normal: No motor fluctuations;Slight: OFF times are predictable all or almost all of the time (greater than 75 percent);Mild: OFF times are predictable most of the time (51-75 percent);Moderate: OFF times are predictable some of the time (26-50 percent);Severe: OFF episodes are rarely predictable (less than 25 percent) Numeric Values

Determine the usual predictability of OFF function whether due to dose, time of day, food intake or other factors. Use the information provided by the patients and caregiver and supplement with your own observations. You will ask if the patient can count on them always coming at a special time, mostly coming at a special time (in which case you will probe further to separate slight from mild), only sometimes coming at a special time or are they totally unpredictable? Narrowing down the percentage will allow you to find the correct answer

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09983 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - get out bed car deep chair score MDSUPDRSGttngOutBedScore Score for the participant's/subject's ability to get out of bed, a car, or a deep chair, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to get out of bed, a car, or a deep chair, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) GETTING OUT OF BED A CAR OR A DEEP CHAIR 0;1;2;3;4 Normal: Not at all (no problems);Slight: I am slow or awkward, but I usually can do it on my first try;Mild: I need more than one try to get up or need occasional help;Moderate: I sometimes need help to get up, but most times I can still do it on my own;Severe: I need help most or all of the time Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10015 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - kinetic tremor right hand score MDSUPDRSKineticTremrRtHndScore Score for the participant's/subject's level of kinetic tremor of the right hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of kinetic tremor of the right hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) KINETIC TREMOR OF THE HANDS 0;1;2;3;4 Normal: No tremor;Slight: Tremor is present but less than 1 cm in amplitude;Mild: Tremor is at least 1 but less than 3 cm in amplitude;Moderate: Tremor is at least 3 but less than 10 cm in amplitude;Severe: Tremor is at least 10 cm in amplitude. Numeric Values

The finger-to-nose maneuver should be performed slowly enough not to hide any tremor that could occur with very fast arm movements. Repeat with the other hand, rating each hand separately. The tremor can be present throughout the movement or as the tremor reaches either target (nose or finger). Rate the highest amplitude seen.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09962 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - anxious mood score MDSUPDRSAnxsMoodScore Score for the participant's/subject's anxious mood over the past week determining if he or she felt nervous, tense, worried or anxious, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's anxious mood over the past week determining if he or she felt nervous, tense, worried or anxious, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) ANXIOUS MOOD 0;1;2;3;4 Normal: No anxious feelings;Slight: Anxious feelings present but not sustained for more than one day at a time. No interference with patient's ability to carry out normal activities and social interactions;Mild: Anxious feelings are sustained over more than one day at a time, but without interference with patient's ability to carry out normal activities and social interactions;Moderate: Anxious feelings interfere with, but do not preclude, the patient's ability to carry out normal activities and social interactions;Severe: Anxious feelings preclude patient's ability to carry out normal activities and social interactions. Numeric Values

Instructions to examiner: Determine nervous, tense, worried or anxious feelings (including panic attacks) over the past week and rate their duration and interference with the patient's ability to carry out daily routines and engage in social interactions. Instructions to patients [and caregiver]: Over the past week have you felt nervous, worried or tense? If yes, was this feeling for longer than one day at a time? Did it make it difficult for you to follow your usual activities or to be with other people? [If yes, examiner asks patient or caregiver to elaborate and probes for information.]

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09994 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - left upper extremity rigid score MDSUPDRSLUERigidScore Score for the participant's/subject's left upper extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's left upper extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) RIGIDTY 0;1;2;3;4 Normal: No rigidity;Slight: Rigidity only detected with activation maneuver;Mild: Rigidity detected without the activation maneuver, but full range of motion is easily achieved;Moderate: Rigidity detected without the activation maneuver| full range of motion is achieved with effort;Severe: Rigidity detected without the activation maneuver and full range of motion not achieved. Numeric Values

First, test without an activation maneuver. Test and rate neck and each limb separately. For arms, test the wrist and elbow joints simultaneously. For legs, test the hip and knee joints simultaneously. If no rigidity is detected, use an activation maneuver such as tapping fingers, fist opening/closing, or heel tapping in a limb not being tested. Explain to the patient to go as limp as possible as you test for rigidity.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10026 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - time spent with dyskinesia score MDSUPDRSTmSpntDyskScore Score for the participant's/subject's time spent with dyskinesia calculated from the total hours awake, total hours with dyskinesia, and percent dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's time spent with dyskinesia calculated from the total hours awake, total hours with dyskinesia, and percent dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) TIME SPENT WITH DYSKINESIAS 0;1;2;3;4 Normal: no dyskinesias;Slight:=25perecent of waking day;Mild: 26-50 percent of waking day;Moderate: 51-75 percent of waking day;Severe: > 75 percent of waking day Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09973 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - speech score MDSUPDRSSpeechScore Score for the participant's/subject's level of speech, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of speech, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) SPEECH 0;1;2;3;4 Normal: Not at all (no problems);Slight: My speech is soft, slurred or uneven, but it does not cause others to ask me to repeat myself;Mild: My speech causes people to ask me to occasionally repeat myself, but not everyday;Moderate: My speech is unclear enough that others ask me to repeat myself every day even though most of my speech is understood;Severe: Most or all of my speech cannot be understood. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10005 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - leg agility right leg score MDSUPDRSLegAgiltyRteLegScore Score for the participant's/subject's right leg agility evaluating speed, amplitude, hesitations, halts and decrementing amplitude Score for the participant's/subject's right leg agility evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as part of the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS). LEG AGILITY 0;1;2;3;4 Normal: No problems;Slight: Any of the following: a) the regular rhythm is broken with one or two interruptions or hesitations of the movement, b) slight slowing, c) amplitude decrements near the end of the task;Mild: Any of the following: a) 3 to 5 interruptions during the movements, b) mild slowness, c) amplitude decrements midway in the task;Moderate: Any of the following: a) more than 5 interruptions during the movement or at least one longer arrest (freeze) in ongoing movement, b) moderate slowing in speed, c) amplitude decrements after the first tap;Severe: Cannot or can only barely perform the task because of slowing, interruptions or decrements Numeric Values

Have the patient sit in a straight-backed chair with arms. The patient should have both feet comfortably on the floor. Test each leg separately. Demonstrate the task, but do not continue to perform the task while the patient is being tested. Rate each side separately, evaluating speed, amplitude, hesitations, halts and decrementing amplitude.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10037 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - painful off state dystonia score MDSUPDRSPainflOffStatDystnaScr Score for the participant's/subject's level of painful off-state dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of painful off-state dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) PAINFUL OFF STATE DYSTONIA 0;1;2;3;4 Normal: No dystonia OR NO OFF TIME;Slight: < 25% of time in OFF state;Mild: 26-50% of time in OFF state;Moderate: 51-75% of time in OFF state;Severe: > 75% of time in OFF state. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09984 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - walk balance score MDSUPDRSWlkngBalanceScore Score for the participant's/subject's ability to walk and balance on his or her own, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to walk and balance on his or her own, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) WALKING AND BALANCE 0;1;2;3;4 Normal: Not at all (no problems);Slight: I am slightly slow or may drag a leg. I never use a walking aid;Mild: I occasionally use a walking aid, but I do not need any help from another person;Moderate: I usually use a walking aid (cane, walker) to walk safely without falling. However, I do not usually need the support of another person;Severe: I usually use the support of another persons to walk safely without falling Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10016 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - kinetic tremor left hand score MDSUPDRSKineticTremrLftHndScr Score for the participant's/subject's level of kinetic tremor of the left hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's level of kinetic tremor of the left hand observing the highest amplitude seen, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) KINETIC TREMOR OF THE HANDS 0;1;2;3;4 Normal: No tremor;Slight: Tremor is present but less than 1 cm in amplitude;Mild: Tremor is at least 1 but less than 3 cm in amplitude;Moderate: Tremor is at least 3 but less than 10 cm in amplitude;Severe: Tremor is at least 10 cm in amplitude. Numeric Values

The finger-to-nose maneuver should be performed slowly enough not to hide any tremor that could occur with very fast arm movements. Repeat with the other hand, rating each hand separately. The tremor can be present throughout the movement or as the tremor reaches either target (nose or finger). Rate the highest amplitude seen.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09963 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - apathy score MDSUPDRSApathyScore Score for the participant's/subject's apathy, considering the level of spontaneous activity, assertiveness, motivation and initiative and how it affects the performance of daily routines, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's apathy, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) APATHY 0;1;2;3;4 Normal: No apathy;Slight: Apathy appreciated by patient and/or caregiver, but no interference with daily activities and social interactions;Mild: Apathy interferes with isolated activities and social interactions;Moderate: Apathy interferes with most activities and social interactions;Severe: Passive and withdrawn, complete loss of initiative. Numeric Values

Instructions to examiner: Consider level of spontaneous activity, assertiveness, motivation and initiative and rate the impact of reduced levels on performance of daily routines and social interactions. Here the examiner should attempt to distinguish between apathy and similar symptoms that are best explained by depression. Instructions to patients (and caregiver): Over the past week, have you felt indifferent to doing activities or being with people? If yes, examiner asks patient or caregiver to elaborate and probes for information.]

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09995 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - right lower extremity rigid score MDSUPDRSRLERigidScore Score for the participant's/subject's right lower extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's right lower extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) RIGIDTY 0;1;2;3;4 Normal: No rigidity;Slight: Rigidity only detected with activation maneuver;Mild: Rigidity detected without the activation maneuver, but full range of motion is easily achieved;Moderate: Rigidity detected without the activation maneuver| full range of motion is achieved with effort;Severe: Rigidity detected without the activation maneuver and full range of motion not achieved. Numeric Values

First, test without an activation maneuver. Test and rate neck and each limb separately. For arms, test the wrist and elbow joints simultaneously. For legs, test the hip and knee joints simultaneously. If no rigidity is detected, use an activation maneuver such as tapping fingers, fist opening/closing, or heel tapping in a limb not being tested. Explain to the patient to go as limp as possible as you test for rigidity.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10027 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - total hours awake number MDSUPDRSTtlHrAwkDyskNum Number of total number of hours the participant/subject stays awake, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Number of total number of hours the participant/subject stays awake, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Total Hours Awake Numeric Values

Value should be recorded between 0-24 hours

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Free-Form Entry

C09974 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - saliva and drool score MDSUPDRSSlivaDroolScore Score for the participant's/subject's ability to control saliva and drool, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to control saliva and drool, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) SALIVA AND DROOLING 0;1;2;3;4 Normal: Not at all (no problems);Slight: I have too much saliva, but do not drool;Mild: I have some drooling during sleep, but none when I am awake;Moderate: I have some drooling when I am awake, but I usually do not need tissues or a handkerchief;Severe: I have so much drooling that I regularly need to use tissues or a handkerchief to protect my clothes. Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10006 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - leg agility left leg score MDSUPDRSLegAgiltyLftLegScore Score for the participant's/subject's left leg agility evaluating speed, amplitude, hesitations, halts and decrementing amplitude Score for the participant's/subject's left leg agility evaluating speed, amplitude, hesitations, halts and decrementing amplitude, as part of the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS). LEG AGILITY 0;1;2;3;4 Normal: No problems;Slight: Any of the following: a) the regular rhythm is broken with one or two interruptions or hesitations of the movement, b) slight slowing, c) amplitude decrements near the end of the task;Mild: Any of the following: a) 3 to 5 interruptions during the movements, b) mild slowness, c) amplitude decrements midway in the task;Moderate: Any of the following: a) more than 5 interruptions during the movement or at least one longer arrest (freeze) in ongoing movement, b) moderate slowing in speed, c) amplitude decrements after the first tap;Severe: Cannot or can only barely perform the task because of slowing, interruptions or decrements Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10038 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - total hour off denominator dystonia number MDSUPDRSTtlHrOffDemnDystniaNum Number of total hours in the off-state that the examiner records to use as the denominator to calculate proportion of Off hours affected by dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Number of total hours in the off-state that the examiner records to use as the denominator to calculate proportion of Off hours affected by dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Total Hours Off Numeric Values

Value should be recorded between 0-24 hours

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Free-Form Entry

C09985 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - freeze score MDSUPDRSFreezingScore Score for the participant's/subject's inability to move because he or she cannot suddenly move the feet, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's inability to move because he or she cannot suddenly move the feet, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Freezing when walking 0;1;2;3;4 Normal: Not at all (no problems);Slight: I briefly freeze but I can easily start walking again. I do not need help from someone else or a walking aid (cane or walker) because of freezing;Mild: I freeze and have trouble starting to walk again, but I do not need someone's help or a walking aid (cane or walker) because of freezing;Moderate: When I freeze I have a lot of trouble starting to walk again and, because of freezing, I sometimes need to use a walking aid or need someone else's help;Severe: Because of freezing, most or all of the time, I need to use a walking aid or someone's help Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10017 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - rest tremor amplitude right upper extremity score MDSUPDRSRestTremorAmpRUEScore Score for the participant's/subject's right upper extremities rest tremor amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's right upper extremities rest tremor amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) REST TREMOR AMPLITUDE 0;1;2;3;4 Normal: No tremor;Slight.: < 1 cm in maximal amplitude;Mild: > 1 cm but < 3 cm in maximal amplitude;Moderate: 3 - 10 cm in maximal amplitude;Severe: > 10 cm in maximal amplitude Numeric Values

Refer to instrument for additional instructions

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09964 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - dopamine dysregulation syndrome score MDSUPDRSDopmnDysregSyndScore Score for the participant's/subject's features of dopamine dysregulation syndrome considering involvement in a variety of activities including atypical or excessive gambling (e.g. casinos or lottery tickets), atypical or excessive sexual drive or interests (e.g., unusual interest in pornography, masturbation, sexual demands on partner), other repetitive activities (e.g. hobbies, dismantling objects, sorting or organizing), or taking extra non-prescribed medication for non-physical reasons (i.e., addictive behavior), as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS). Score for the participant's/subject's features of dopamine dysregulation syndrome considering involvement in a variety of activities, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS). FEATURES OF DOPAMINE DYSREGULATION SYNDROME 0;1;2;3;4 Normal: No problems present;Slight: Problems are present but usually do not cause any difficulties for the patient or family/caregiver;Mild: Problems are present and usually cause a few difficulties in the patient's personal and family life;Moderate: Problems are present and usually cause a lot of difficulties in the patient's personal and family life;Severe: Problems are present and preclude the patient's ability to carry out normal activities or social interactions or to maintain previous standards in personal and family life. Numeric Values

Give patient examples such as gambling, cleaning, using the computer, taking extra medicine, obsessing about food or sex, all depending on the patients.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C09996 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - left lower extremity rigid score MDSUPDRSLLERigidScore Score for the participant's/subject's lower left extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's lower left extremities rigidity, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) RIGIDTY 0;1;2;3;4 Normal: No rigidity;Slight: Rigidity only detected with activation maneuver;Mild: Rigidity detected without the activation maneuver, but full range of motion is easily achieved;Moderate: Rigidity detected without the activation maneuver| full range of motion is achieved with effort;Severe: Rigidity detected without the activation maneuver and full range of motion not achieved. Numeric Values

First, test without an activation maneuver. Test and rate neck and each limb separately. For arms, test the wrist and elbow joints simultaneously. For legs, test the hip and knee joints simultaneously. If no rigidity is detected, use an activation maneuver such as tapping fingers, fist opening/closing, or heel tapping in a limb not being tested. Explain to the patient to go as limp as possible as you test for rigidity.

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10028 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - total hours with dyskinesia number MDSUPDRSTtlHrDyskNum Number of total number of hours the participant/subject has dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Number of total number of hours the participant/subject has dyskinesia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Total Hours with Dyskinesia Numeric Values

Value should be recorded between 0-24 hours

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

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C09975 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - chew swallow score MDSUPDRSChwngSwllwngScore Score for the participant's/subject's ability to chew and swallow food, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to chew and swallow food, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) CHEWING AND SWALLOWING 0;1;2;3;4 Normal: No problems;Slight: I am aware of slowness in my chewing or increased effort at swallowing, but I do not choke or need to have my food specially prepared;Mild: I need to have my pills cut or my food specially prepared because of chewing or swallowing problems, but I have not choked over the past week;Moderate. I choked at least once in the past week;Severe: Because of chewing and swallowing problems, I need a feeding tube. Numeric Values

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URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10007 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - arise from chair score MDSUPDRSArisingFrmChrScore Score for the participant's/subject's ability to arise from a chair observing the posture, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's ability to arise from a chair observing the posture, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) ARISING FROM CHAIR 0;1;2;3;4 Normal: No problems. Able to arise quickly without hesitation;Slight: Arising is slower than normal, or may need more than one attempt, or may need to move forward in the chair to arise. No need to use the arms of the chair;Mild: Pushes self up from arms of chair without difficulty.;Moderate: Needs to push off, but tends to fall back or may have to try more than one time using arms of chair, but can get up without help.;Severe: Unable to arise without help. Numeric Values

Have the patient sit in a straight-backed chair with arms, with both feet on the floor and sitting back in the chair (if the patient is not too short). Allow only one attempt in this situation. If unsuccessful, allow the patient to push off using his/her hands on the arms of the chair. Allow a maximum of three trials of pushing off. If still not successful, assist the patient to arise. After the patient stands up, observe the posture for item 3.13

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10039 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - total hour off with dystonia number MDSUPDRSTtlHrOffWDystniaNum Number of total hours that the participant/subject is Off with dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Number of total hours that the participant/subject is Off with dystonia, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Total Off Hours with Dystonia Numeric Values

You have already determined the number of hours of "OFF" time (4.3). Of these hours, determine how many are associated with dystonia. If there is no OFF time, mark 0. Value should be recorded between 0-24 hours

URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Free-Form Entry

C09986 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - patient on medication for Parkinson indicator MDSUPDRSPtntPrknsnMedInd Indicator for whether the participant/subject is on medication for treating the symptoms of Parkinson's Disease, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Indicator for whether the participant/subject is on medication for treating the symptoms of Parkinson's Disease, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Is the patient on medication for treating the symptoms of Parkinson's Disease? No;Yes No;Yes Alphanumeric

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URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

C10018 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) - rest tremor amplitude left upper extremity score MDSUPDRSRestTremorAmpLUEScore Score for the participant's/subject's left upper extremities rest tremor amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) Score for the participant's/subject's left upper extremities rest tremor amplitude, as a part of Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS UPDRS) REST TREMOR AMPLITUDE 0;1;2;3;4 Normal: No tremor;Slight.: < 1 cm in maximal amplitude;Mild: > 1 cm but < 3 cm in maximal amplitude;Moderate: 3 - 10 cm in maximal amplitude;Severe: > 10 cm in maximal amplitude Numeric Values

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URL:http://www.movementdisorders.org/MDS-Files1/Resources/PDFs/MDS-UPDRS.pdf Adult Core 3.00 2013-07-22 09:34:41.527 Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Motor Function Outcomes and End Points

Single Pre-Defined Value Selected

CSV