CDE Detailed Report
Disease: Parkinson's Disease
Sub-Domain: Other Clinical Data
CRF: Neuropathology
Displaying 1 - 50 of 83
Sub-Domain: Other Clinical Data
CRF: Neuropathology
Displaying 1 - 50 of 83
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Additional Notes (Question Text) | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guideline) | Sub Domain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C08206 | Frontotemporal Lobar Degeneration (FTLD) - type indicator | FTLDTypInd | Whether the specific type of FTLD is present | Whether the specific type of FTLD is present | Is another type of FTLD present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Answered only if Question 39 (Is another type of FTLD present?) is answered YES. |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08171 | Diffuse plaques density category | DiffusePlaqDenstyCat | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Density of diffuse plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | Diffuse Plaques (plaques with non-compact amyloid and no apparent dystrophic neurites) | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | No plaques;Sparse plaques;Moderate plaques;Frequent plaques;Not assessed;Unknown | Alphanumeric |
Choose one |
MIRRA, S. S., HEYMAN, A., MCKEEL, D., SUMI, S. M., CRAIN, B. J., BROWNLEE, L. M., VOGEL, F. S., HUGHES, J. P., VAN BELLE, G. & BERG, L. 1991. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology, 41, 479-86. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08183 | Atherosclerotic vascular pathology severity scale | AthrsclrtcVasclrPthlgySvrtyScl | Whether or not atherosclerotic vascular pathology (of the circle of Willis) is present and if so, its severity | Whether or not atherosclerotic vascular pathology (of the circle of Willis) is present and if so, its severity | Is atherosclerotic vascular pathology (of the circle of Willis) present? | None;Mild;Moderate;Severe;Not assessed;Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | Alphanumeric |
Choose one |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17423 | Spinocerebellar degeneration type text | SpinDegTypTxt | Text area to describe the type of spinocerebellar degenerations | Text area to describe the type of spinocerebellar degenerations | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C08148 | Neuropath specimen identifier number | NeuropthSpecmnIDNum | Unique identification number given to the neuropathology specimen | Unique identification number given to the neuropathology specimen | Neuropath ID | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C08195 | Frontotemporal degeneration tau pathology indicator | FrntmprlDgnrtnTauPathlgyInd | Indicator of whether frontotemporal degeneration with tau pathology is present | Indicator of whether frontotemporal degeneration with tau pathology is present | Is frontotemporal degeneration with tau pathology present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
If no, skip to Question 35 |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18754 | Spinocerebellar degeneration specify text | SpinocrblrDegnrtnST | The free-text field related to 'Spinocerebellar degeneration indicator specify text'. Indicator of whether the participant/subject has spinocerebellar degenerations | The free-text field related to 'Spinocerebellar degeneration indicator specify text'. Indicator of whether the participant/subject has spinocerebellar degenerations | Yes, specify | Alphanumeric |
No instructions available |
GWINN-HARDY, K., CHEN, J. Y., LIU, H. C., LIU, T. Y., BOSS, M., SELTZER, W., ADAM, A., SINGLETON, A., KOROSHETZ, W., WATERS, C., HARDY, J. & FARRER, M. 2000. Spinocerebellar ataxia type 2 with parkinsonism in ethnic Chinese. Neurology, 55, 800-5. GWINN-HARDY, K., SINGLETON, A., O'SUILLEABHAIN, P., BOSS, M., NICHOLL, D., ADAM, A., HUSSEY, J., CRITCHLEY, P., HARDY, J. & FARRER, M. 2001. Spinocerebellar ataxia type 3 phenotypically resembling parkinson disease in a black family. Arch Neurol, 58, 296-9. | Adult | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C08161 | Hydrocephalus severity scale | HydrcephlsSevrtyScale | Scale of the severity of the hydrocephalus | Scale of the severity of the hydrocephalus | Hydrocephalus | None;Mild;Moderate;Severe;Not assessed;Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08172 | Beta-amyloidal plaque accumulation stage | BetaAmyldlPlaqAccmltnStage | Extent of beta-amyloidal plaque accumulation through the brain | Extent of beta-amyloidal plaque accumulation through the brain | Amyloid phase | Phase I (cortex);Phase 2 (cortex and hippocampus);Phase 3 (cortex, hippocampus, and basal ganglia);Phase 4 (cortex, hippocampus, basal ganglia, and brainstem);Phase 5 (cortex, hippocampus, basal ganglia, brainstem, and cerebellum);Amyloid plaques not present;Incompletely assessed;Not assessed;Unknown | Phase I (cortex);Phase 2 (cortex and hippocampus);Phase 3 (cortex, hippocampus, and basal ganglia);Phase 4 (cortex, hippocampus, basal ganglia, and brainstem);Phase 5 (cortex, hippocampus, basal ganglia, brainstem, and cerebellum);Amyloid plaques not present;Incompletely assessed;Not assessed;Unknown | Alphanumeric |
Choose one |
ALAFUZOFF, I., THAL, D. R., ARZBERGER, T., BOGDANOVIC, N., AL-SARRAJ, S., BODI, I., BOLUDA, S., BUGIANI, O., DUYCKAERTS, C., GELPI, E., GENTLEMAN, S., GIACCONE, G., GRAEBER, M., HORTOBAGYI, T., HOFTBERGER, R., INCE, P., IRONSIDE, J. W., KAVANTZAS, N., KING, A., KORKOLOPOULOU, P., KOVACS, G. G., MEYRONET, D., MONORANU, C., NILSSON, T., PARCHI, P., PATSOURIS, E., PIKKARAINEN, M., REVESZ, T., ROZEMULLER, A., SEILHEAN, D., SCHULZ-SCHAEFFER, W., STREICHENBERGER, N., WHARTON, S. B. & KRETZSCHMAR, H. 2009b. Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium. Acta Neuropathol, 117, 309-20. THAL, D. R., RUB, U., ORANTES, M. & BRAAK, H. 2002. Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology, 58, 1791-800. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08207 | Transmissible spongiform encephalopathy indicator | TransmssblSpngfrmEncphlpthyInd | Whether or not pathology is consistent with transmissible spongiform encephalopathy | Whether or not pathology is consistent with transmissible spongiform encephalopathy | Is there a pathology consistent with transmissible spongiform encephalopathy | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
If no, skip to Question 41 |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08184 | Arteriosclerosis severity scale | ArtrScalersisSevScl | Whether or not arteriosclerosis (small parenchymal arteriolar disease) is present and if so, its severity | Whether or not arteriosclerosis (small parenchymal arteriolar disease) is present and if so, its severity | Is arteriosclerosis (small parenchymal arteriolar disease) present? | None;Mild;Moderate;Severe;Not assessed;Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | Alphanumeric |
Choose one |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18030 | Neuritic plaque brain region score anatomic site | NeurtcPlaqBrnRegnScoreAnatcSit | The anatomic site as it relates to the region in the brain where the neuritic plaques were scored | The anatomic site as it relates to the region in the brain where the neuritic plaques were scored | Region of brain neuritic plaques scored | Left;Right;Both;N/A | Left;Right;Both;N/A | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08149 | Diagnosis final clinical death type | DiagnosFinalClinDeathTyp | Physician's final clinical diagnosis for the participant/subject | Physician's final clinical diagnosis for the participant/subject | Final Clinical Diagnosis Before Death | Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Other, specify;Chorea gravidarum;Dentato-rubro-pallido-luysian atrophy (DRPLA), with genetically confirmed expansion of CAG repeats;Dentato-rubro-pallido-luysian atrophy (DRPLA), without genetically confirmed expansion of CAG repeats;Fragile X syndrome with genetically confirmed expansion of CGG repeats;Fragile X syndrome without genetically confirmed expansion of CGG repeats;Friedreich ataxia with genetically confirmed expansion of GAA repeats;Friedreich ataxia without genetically confirmed expansion of GAA repeats;Frontotemporal lobar degeneration;Hepatolenticular degeneration or Wilson disease;Huntington disease with genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease without genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease-like 2 genetically confirmed expansion of trinucleotide repeats;Huntington disease-like without genetically confirmed expansion of trinucleotide repeats;Kennedy disease with genetically confirmed expansion of CAG repeats;Kennedy disease without genetically confirmed expansion of CAG repeats;Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome);Senile chorea or vascular chorea;Spinocerebellar ataxia with genetically confirmed expansion of either CAG or CTG repeats;Spinocerebellar ataxia without genetically confirmed expansion of either CAG or CTG repeats;Subacute sclerosing panencephalitis;Sydenham chorea;Tardive dyskinesia;Neuroacanthocytosis;Pick disease | Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Other, specify;Chorea gravidarum;Dentato-rubro-pallido-luysian atrophy (DRPLA), with genetically confirmed expansion of CAG repeats;Dentato-rubro-pallido-luysian atrophy (DRPLA), without genetically confirmed expansion of CAG repeats;Fragile X syndrome with genetically confirmed expansion of CGG repeats;Fragile X syndrome without genetically confirmed expansion of CGG repeats;Friedreich ataxia with genetically confirmed expansion of GAA repeats;Friedreich ataxia without genetically confirmed expansion of GAA repeats;Frontotemporal lobar degeneration;Hepatolenticular degeneration or Wilson disease;Huntington disease with genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease without genetically confirmed expansion of HD-IT15 CAG repeats;Huntington disease-like 2 genetically confirmed expansion of trinucleotide repeats;Huntington disease-like without genetically confirmed expansion of trinucleotide repeats;Kennedy disease with genetically confirmed expansion of CAG repeats;Kennedy disease without genetically confirmed expansion of CAG repeats;Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome);Senile chorea or vascular chorea;Spinocerebellar ataxia with genetically confirmed expansion of either CAG or CTG repeats;Spinocerebellar ataxia without genetically confirmed expansion of either CAG or CTG repeats;Subacute sclerosing panencephalitis;Sydenham chorea;Tardive dyskinesia;Neuroacanthocytosis;Pick disease | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C08196 | Tauopathy disease type | TaupthyDisTyp | Presence of disease resulting from the pathological aggregation of tau protein | Presence of disease resulting from the pathological aggregation of tau protein | Tauopathies | Pick's Disease;Corticobasal degeneration;Progressive supranuclear palsy;Argyrophilic grain dementia (including diffuse AGD);Other 4R tauopathy (e.g., multisystem tauopathy);Tangle-predominant dementia (including Parkinson dementia complex) | Pick's Disease;Corticobasal degeneration;Progressive supranuclear palsy;Argyrophilic grain dementia (including diffuse AGD);Other 4R tauopathy (e.g., multisystem tauopathy);Tangle-predominant dementia (including Parkinson dementia complex) | Alphanumeric |
No instructions available |
DICKSON, D. W. 1998. Pick's disease: a modern approach. Brain Pathol, 8, 339-54. DICKSON, D. W., BERGERON, C., CHIN, S. S., DUYCKAERTS, C., HOROUPIAN, D., IKEDA, K., JELLINGER, K., LANTOS, P. L., LIPPA, C. F., MIRRA, S. S., TABATON, M., VONSATTEL, J. P., WAKABAYASHI, K. & LITVAN, I. 2002. Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol, 61, 935-46. LANTOS, P. L. 1994. The neuropathology of progressive supranuclear palsy. J Neural Transm Suppl, 42, 137-52. TOLNAY, M. & CLAVAGUERA, F. 2004. Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies. Neuropathology, 24, 269-83. BIGIO, E. H., LIPTON, A. M., YEN, S. H., HUTTON, M. L., BAKER, M., NACHARAJU, P., WHITE, C. L., 3RD, DAVIES, P., LIN, W. & DICKSON, D. W. 2001. Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. J Neuropathol Exp Neurol, 60, 328-41. KOVACS, G. G., MAJTENYI, K., SPINA, S., MURRELL, J. R., GELPI, E., HOFTBERGER, R., FRASER, G., CROWTHER, R. A., GOEDERT, M., BUDKA, H. & GHETTI, B. 2008. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J Neuropathol Exp Neurol, 67, 963-75. JELLINGER, K. A. & BANCHER, C. 1998. Senile dementia with tangles (tangle predominant form of senile dementia). Brain Pathol, 8, 367-76. HOF, P. R., PERL, D. P., LOERZEL, A. J. & MORRISON, J. H. 1991. Neurofibrillary tangle distribution in the cerebral cortex of parkinsonism-dementia cases from Guam: differences with Alzheimer's disease. Brain Res, 564, 306-13. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18766 | Tauopathy not specified incompletely characterized specify text | TpthyNtSpcfdIncmpltChrctrzdST | The free-text field related to 'Tauopathy not specified incompletely characterized indicator'. Whether or not there participant/subject has an tauopathy that is not specified or incompletely characterized | The free-text field related to 'Tauopathy not specified incompletely characterized indicator'. Whether or not there participant/subject has an tauopathy that is not specified or incompletely characterized | Yes, specify | Alphanumeric |
Choose one |
No references available | Adult | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C08162 | National Institute on Aging (NIA) or Reagan Institute neuropathological criteria scale | NIAReaganInNeuropathCritScale | National Institute on Aging (NIA)/Reagan Institute neuropathological criteria used to determine the likelihood of dementia being due to Alzheimer's disease. | National Institute on Aging (NIA)/Reagan Institute neuropathological criteria used to determine the likelihood of dementia being due to Alzheimer's disease. | NIA/Reagan Institute neuropathological criteria | Low likelihood of dementia being due to Alzheimer's disease;Intermediate likelihood of dementia being due to Alzheimer's disease;High likelihood of dementia being due to Alzheimer's disease;Criteria not met;Not assessed;Unknown | Low likelihood of dementia being due to Alzheimer's disease;Intermediate likelihood of dementia being due to Alzheimer's disease;High likelihood of dementia being due to Alzheimer's disease;Criteria not met;Not assessed;Unknown | Alphanumeric | HYMAN, B. T. & TROJANOWSKI, J. Q. 1997. Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08173 | Ischemic hemorrhagic or vascular pathology indicator | IschHemVasclPathInd | Indicator of the presence of ischemic, hemorrhagic, or vascular pathology | Indicator of the presence of ischemic, hemorrhagic, or vascular pathology | Is ischemic, hemorrhagic or vascular pathology present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
If no,skip to Question 24 |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08209 | Creutzfeldt-Jakob disease variant indicator | CrtzfldtJkbDisVarntInd | Whether or not Creutzfeldt-Jakob disease (CJD) or variant CJD is present | Whether or not Creutzfeldt-Jakob disease (CJD) or variant CJD is present | Is Creutzfeldt-Jakob disease or variant CJD present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Answered only if Question 40 (Is there pathology consistent with transmissible spongiform encephalopathy?) is answered YES. |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08185 | Amyloid angiopathy severity scale | AmyldAngpthySevScale | Whether or not amyloid deposits are present in the walls of the blood vessels of the central nervous system and if so, their severity. | Whether or not amyloid deposits are present in the walls of the blood vessels of the central nervous system and if so, their severity. | Is amyloid angiopathy present? | None;Mild;Moderate;Severe;Not assessed;Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | Alphanumeric |
Choose one |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18031 | Diffuse plaques brain region score anatomic site | DiffsePlaqBrainRgnScorAntmSite | The anatomic site as it relates to the region in the brain where the diffuse plaques were scored | The anatomic site as it relates to the region in the brain where the diffuse plaques were scored | Region of brain diffuse plaques scored | Left;Right;Both;N/A | Left;Right;Both;N/A | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08151 | Diagnosis final clinical death date | DiagnosFinalClinDeathDate | Date of participant's/subject's final clinical diagnosis | Date of participant's/subject's final clinical diagnosis | Date of final diagnosis | Date or Date & Time | ISO 8601 - http://www.iso.org/iso/iso_catalogue.htm | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
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| C08197 | Tauopathy degeneration indicator | TaupthyDegnrtnInd | Indicator of whether degeneration was assessed for the specific type of Tauopathy disease | Indicator of whether degeneration was assessed for the specific type of Tauopathy disease | Yes, No, Not assessed, Unknown | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Answer for each type of taupathy if Question 34 (Is frontotemporal degeneration with tau pathology present?) is answered YES |
DICKSON, D. W. 1998. Pick's disease: a modern approach. Brain Pathol, 8, 339-54. DICKSON, D. W., BERGERON, C., CHIN, S. S., DUYCKAERTS, C., HOROUPIAN, D., IKEDA, K., JELLINGER, K., LANTOS, P. L., LIPPA, C. F., MIRRA, S. S., TABATON, M., VONSATTEL, J. P., WAKABAYASHI, K. & LITVAN, I. 2002. Office of Rare Diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol, 61, 935-46. LANTOS, P. L. 1994. The neuropathology of progressive supranuclear palsy. J Neural Transm Suppl, 42, 137-52. TOLNAY, M. & CLAVAGUERA, F. 2004. Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies. Neuropathology, 24, 269-83. BIGIO, E. H., LIPTON, A. M., YEN, S. H., HUTTON, M. L., BAKER, M., NACHARAJU, P., WHITE, C. L., 3RD, DAVIES, P., LIN, W. & DICKSON, D. W. 2001. Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia. J Neuropathol Exp Neurol, 60, 328-41. KOVACS, G. G., MAJTENYI, K., SPINA, S., MURRELL, J. R., GELPI, E., HOFTBERGER, R., FRASER, G., CROWTHER, R. A., GOEDERT, M., BUDKA, H. & GHETTI, B. 2008. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J Neuropathol Exp Neurol, 67, 963-75. JELLINGER, K. A. & BANCHER, C. 1998. Senile dementia with tangles (tangle predominant form of senile dementia). Brain Pathol, 8, 367-76. HOF, P. R., PERL, D. P., LOERZEL, A. J. & MORRISON, J. H. 1991. Neurofibrillary tangle distribution in the cerebral cortex of parkinsonism-dementia cases from Guam: differences with Alzheimer's disease. Brain Res, 564, 306-13. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C19247 | Subject ID | SubIDNam | Subject identification ID | Subject identification ID | MDS/UDS Patient ID | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-06-05 13:10:49.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C08163 | CERAD neuropathological criteria scale | CERADNeuropathCritScale | CERAD neuropathological criteria used to determine the probability of the participant/subject having Alzheimer's disease | Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropathological criteria used to determine the probability of the participant/subject having Alzheimer's disease | CERAD neuropathological criteria | Possible Alzheimer's disease;Probable Alzheimer's disease;Definite Alzheimer's disease;Criteria not met;Not assessed;Unknown | Possible Alzheimer's disease;Probable Alzheimer's disease;Definite Alzheimer's disease;Criteria not met;Not assessed;Unknown | Alphanumeric | MIRRA, S. S., HEYMAN, A., MCKEEL, D., SUMI, S. M., CRAIN, B. J., BROWNLEE, L. M., VOGEL, F. S., HUGHES, J. P., VAN BELLE, G. & BERG, L. 1991. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropath | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08174 | Large artery cerebral infarct indicator | LrgArtryCerbrlInfarcInd | Indicator of the presence of one or more infarcts larger than 1 cm in diameter in the distribution of large and medium sized meningocerebral vessels rather than small parenchymal vessels | Indicator of the presence of one or more infarcts larger than 1 cm in diameter in the distribution of large and medium sized meningocerebral vessels rather than small parenchymal vessels | Are on ore more large artery cerebral infarcts present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Infarcts meeting these criteria are included regardless of the histologic age and include acute lesions as well as chronic cystic lesions 'Only answered if Question 23 (Is ischemic, hemorrhagic or vascular pathology present?) was answered YES |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08210 | Prion disease other indicator | PrionDisOthrInd | Whether or not another prion disease (besides Creutzfeldt-Jakob disease or variant CJD) is present | Whether or not another prion disease (besides Creutzfeldt-Jakob disease or variant CJD) is present | Are other prion diseases present (e.g., Gerstmann-Straussler syndrome)? | Yes, specify;No;Not assessed;Unknown | Yes, specify;No;Not assessed;Unknown | Alphanumeric |
Answered only if Question 40 (Is there pathology consistent with transmissible spongiform encephalopathy?) is answered YES. Choose one. If YES is answered then specify the other prion disease. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08186 | Other angiopathy type indicator | OthrAngpthyTypInd | Whether or not another type of angiopathy (e.g., CADASIL or arteritis) is present | Whether or not another type of angiopathy (e.g., CADASIL or arteritis) is present | Is another type of angiopathy (e.g., CADASIL or arteritis) present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Choose one |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18032 | Other major pathologic disorder name | OthrMjrPathlgcDisordrNam | Names of the other major pathologic disorders present. | Names of the other major pathologic disorders present. | List other disorders | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-20 10:46:24.96 | Neuropathology | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C08152 | Brain tissue frozen indicator | BrainTissFrozenInd | Indicator of whether banked frozen brain tissue is accessible | Indicator of whether banked frozen brain tissue is accessible | Is banked frozen brain tissue accessible? | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08198 | Tauopathy not specified incompletely characterized indicator | TpthyNtSpcfdIncmpltChrctrzdInd | Whether or not there participant/subject has an tauopathy that is not specified or incompletely characterized | Whether or not there participant/subject has an tauopathy that is not specified or incompletely characterized | Other Tauopathies | Yes, specify;No;Not assessed;Unknown | Yes, specify;No;Not assessed;Unknown | Alphanumeric |
Choose one |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08164 | ADRDA Khachaturian neuropathological criteria result | ADRDAKhachtrnNeuropthCritrRes | ADRDA/Khachaturian neuropathological criteria used to determine whether or not the participant/subject has Alzheimer's disease | ADRDA/Khachaturian neuropathological criteria used to determine whether or not the participant/subject has Alzheimer's disease | ADRDA/Khachaturian neuropathological critera | Alzheimer's disease;Criteria not met;Not assessed;Unknown | Alzheimer's disease;Criteria not met;Not assessed;Unknown | Alphanumeric | KHACHATURIAN, Z. S. 1985. Diagnosis of Alzheimer's disease. Arch Neurol, 42, 1097-105. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08175 | Cortical microinfarct indicator | CortclMicroinfarcInd | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Indicator of the presence of one or more infarcts that are detected microscopically (including "granular atrophy") and may not be grossly visible, or may appear to the naked eye as cortical granularity | Are one or more cortical microinfarcts (including "granular atrophy") present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Infarcts meeting these criteria are included regardless of the histologic age and include acute lesions as well as chronic cystic lesions. 'Microinfarcts in non-cortical areas should not be included in this category. 'Only answered if Question 23 (Is ischemic, hemorrhagic or vascular pathology present?) was answered YES |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08211 | Pathologic disorder other indicator | PatholgcDisordrOthrInd | Whether or not there are other major pathologic disorders that are present | Whether or not there are other major pathologic disorders that are present | Are other major pathologic disorders present (not addressed)? | Yes, specify;No;Not assessed;Unknown | Yes, specify;No;Not assessed;Unknown | Alphanumeric |
Choose one. If YES is answered then specify the other major pathologic disorder. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08187 | Lewy body pathology indicator | LewyBdyPathlgyInd | Whether or not Lewy body pathology is present | Whether or not Lewy body pathology is present | Is Lewy body pathology present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
If no,skip to Question 31 |
BEACH, T. G., WHITE, C. L., HAMILTON, R. L., DUDA, J. E., IWATSUBO, T., DICKSON, D. W., LEVERENZ, J. B., RONCAROLI, F., BUTTINI, M., HLADIK, C. L., SUE, L. I., NOORIGIAN, J. V. & ADLER, C. H. 2008. Evaluation of alpha-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol, 116, 277-88. ALAFUZOFF, I., PARKKINEN, L., AL-SARRAJ, S., ARZBERGER, T., BELL, J., BODI, I., BOGDANOVIC, N., BUDKA, H., FERRER, I., GELPI, E., GENTLEMAN, S., GIACCONE, G., KAMPHORST, W., KING, A., KORKOLOPOULOU, P., KOVACS, G. G., LARIONOV, S., MEYRONET, D., MONORANU, C., MORRIS, J., PARCHI, P., PATSOURIS, E., ROGGENDORF, W., SEILHEAN, D., STREICHENBERGER, N., THAL, D. R. & KRETZSCHMAR, H. 2008. Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol, 67, 125-43. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18667 | Data source other text | DataSourcOTH | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | Other, specify | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C08153 | Brain tissue formalin-fixed indicator | BrainTissFormalinFixedInd | Indicator of whether formalin-fixed brain tissue is accessible | Indicator of whether formalin-fixed brain tissue is accessible | Is formalin-fixed brain tissue accessible? | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08200 | Abnormal TPD-43 pathology indicator | AbnrmlTPD43PathlgyInd | Whether or not abnormal TPD-43 pathology is present | Whether or not abnormal TPD-43 pathology is present | Is abnormal TDP-43 pathology present | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Choose one |
CAIRNS, N. J., BIGIO, E. H., MACKENZIE, I. R., NEUMANN, M., LEE, V. M., HATANPAA, K. J., WHITE, C. L., 3RD, SCHNEIDER, J. A., GRINBERG, L. T., HALLIDAY, G., DUYCKAERTS, C., LOWE, J. S., HOLM, I. E., TOLNAY, M., OKAMOTO, K., YOKOO, H., MURAYAMA, S., WOULFE, J., MUNOZ, D. G., DICKSON, D. W., INCE, P. G., TROJANOWSKI, J. Q. & MANN, D. M. 2007. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (Berl), 114, 5-22. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08165 | Other unspecific neuropathological criteria result | OthrUnspcfcNeuropthCritrReslt | Other or unspecified neuropathological criteria used to determine whether or not the participant/subject has Alzheimer's disease | Other or unspecified neuropathological criteria used to determine whether or not the participant/subject has Alzheimer's disease | Other or unspecified criteria | Alzheimer's disease, unspecified;Criteria not met;Not assessed;Unknown | Alzheimer's disease, unspecified;Criteria not met;Not assessed;Unknown | Alphanumeric | No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08176 | Lacunes single or multiple indicator | LacunesSingMultiInd | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels, most often in basal ganglia, thalamus, pons, cerebellum and cerebral white matter | Indicator of the presence of one or more cystic/old infarcts or hemorrhages 1-cm or less in diameter that are usually grossly identified and in the distribution of small parenchymal vessels. | Are one or more lacunes (small artery infarcts and/or hemorrhages) present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Only answered if Question 23 (Is ischemic, hemorrhagic or vascular pathology present?) was answered YES |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08213 | Pathologic diagnosis responsible cognitive status type | PthgcDgnsisRspCgntvStatTyp | Type of pathologic diagnosis or feature which is assessed for its relationship to the participant's/subject's cognitive status | Type of pathologic diagnosis or feature which is assessed for its relationship to the participant's/subject's cognitive status | What are the primary and contributing pathologic diagnoses or features which you judge to be responsible for the subject's cognitive status? | No significant pathology;AD pathology present but insufficient for AD diagnosis;Alzheimer disease (AD);Lewy body disease;Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Vascular disease;FTLD-TDP;FTLD-Taupathies;Hydrocephalus;Prion-associated disease;Huntington's disease (HD);Neurodegeneration with brain iron accumulation;Other, specify | No significant pathology;AD pathology present but insufficient for AD diagnosis;Alzheimer disease (AD);Lewy body disease;Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;Vascular disease;FTLD-TDP;FTLD-Taupathies;Hydrocephalus;Prion-associated disease;Huntington's disease (HD);Neurodegeneration with brain iron accumulation;Other, specify | Alphanumeric |
Code the primary diagnoses or features with a 1. Code the contributing diagnoses or features with a 2. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C08188 | Lewy related pathology anatomic site | LewyReltPathlgyAntmicSite | Brain region where Lewy body pathology was assessed | Brain region where Lewy body pathology was assessed | Density of "Lewy related pathology present" by regions | Sympathetic ganglia (paravertebral);Parasympathetic ganglia (GI, GU);Spinal Cord;Olfactory bulb;Dorsal motor nucleus/glossopharyngeal;Locus ceruleus;Raphe;Substantia nigra;pars compacta;Amygdala;Basal nucleus/diagonal band;Hypothalamus;Caudate/putamen;Entorhinal cortex;Cingulate cortex;Hippocampus;Temporal cortex;Frontal cortex;Parietal cortex;Primary cortex (motor and/or visual) | Sympathetic ganglia (paravertebral);Parasympathetic ganglia (GI, GU);Spinal Cord;Olfactory bulb;Dorsal motor nucleus/glossopharyngeal;Locus ceruleus;Raphe;Substantia nigra;pars compacta;Amygdala;Basal nucleus/diagonal band;Hypothalamus;Caudate/putamen;Entorhinal cortex;Cingulate cortex;Hippocampus;Temporal cortex;Frontal cortex;Parietal cortex;Primary cortex (motor and/or visual) | Alphanumeric |
No instructions available |
BEACH, T. G., WHITE, C. L., HAMILTON, R. L., DUDA, J. E., IWATSUBO, T., DICKSON, D. W., LEVERENZ, J. B., RONCAROLI, F., BUTTINI, M., HLADIK, C. L., SUE, L. I., NOORIGIAN, J. V. & ADLER, C. H. 2008. Evaluation of alpha-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol, 116, 277-88. ALAFUZOFF, I., PARKKINEN, L., AL-SARRAJ, S., ARZBERGER, T., BELL, J., BODI, I., BOGDANOVIC, N., BUDKA, H., FERRER, I., GELPI, E., GENTLEMAN, S., GIACCONE, G., KAMPHORST, W., KING, A., KORKOLOPOULOU, P., KOVACS, G. G., LARIONOV, S., MEYRONET, D., MONORANU, C., MORRIS, J., PARCHI, P., PATSOURIS, E., ROGGENDORF, W., SEILHEAN, D., STREICHENBERGER, N., THAL, D. R. & KRETZSCHMAR, H. 2008. Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol, 67, 125-43. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18669 | Diagnosis final clinical death other text | DiagnosFinalClinDeathOTH | The free-text field related to 'Diagnosis final clinical death type' specifying other text. Physician's final clinical diagnosis for the participant/subject | The free-text field related to 'Diagnosis final clinical death type' specifying other text. Physician's final clinical diagnosis for the participant/subject | Other, specify | Alphanumeric | No references available | Adult | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C08154 | Brain tissue paraffin-embedded indicator | BrainTissParaffinEmbeddedInd | Indicator of whether paraffin-embedded blocks of brain tissue are accessible | Indicator of whether paraffin-embedded blocks of brain tissue are accessible | Are paraffin-embedded blocks of brain tissue accessible? | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08201 | Hippocampal sclerosis indicator | HippcmplSclrsisInd | Whether or not the participant/subject has hippocampal sclerosis of the elderly associated with TDP-43 pathology | Whether or not the participant/subject has hippocampal sclerosis of the elderly associated with TDP-43 pathology | Hippocampal sclerosis of the elderly associated with TDP-43 pathology | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Choose one |
AMADOR-ORTIZ, C., LIN, W. L., AHMED, Z., PERSONETT, D., DAVIES, P., DUARA, R., GRAFF-RADFORD, N. R., HUTTON, M. L. & DICKSON, D. W. 2007. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol, 61, 435-45. | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08166 | Brain atrophy Braak and Braak neurofibrillary stage | BrAtBraakBraakNeurofibStage | Stages I and II correspond to NFT limited to the transentorhinal/entorhinal region; Stages III and IV to limbic stages; and Stages V and VI to neocortical stages. Stage VI implies involvement of primary cortices. | Stages I and II correspond to NFT limited to the transentorhinal/entorhinal region; Stages III and IV to limbic stages; and Stages V and VI to neocortical stages. Stage VI implies involvement of primary cortices. | Braak and Braak Neurofibrillary Stage | Stage I;Stage II;Stage III;Stage IV;Stage V;Stage VI;Neurofibrillary degeneration not present;Not assessed;Unknown | Stage I;Stage II;Stage III;Stage IV;Stage V;Stage VI;Neurofibrillary degeneration not present;Not assessed;Unknown | Alphanumeric |
Answer 'Not Assessed' if topographic staging has not been done. |
BRAAK, H. & BRAAK, E. 1991. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol (Berl), 82, 239-59. BRAAK, H. & BRAAK, E. 1997. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging, 18, 351-7. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08177 | Hemorrhage indicator | HemrrhgInd | Indicator of the presence of cerebral hemorrhages, regardless of size in any region of the brain | Indicator of the presence of cerebral hemorrhages, regardless of size in any region of the brain | Are single or multiple hemorrhages present? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
Only answered if Question 23 (Is ischemic, hemorrhagic or vascular pathology present?) was answered YES |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08214 | Pathologic diagnosis extrapyramidal movement type | PthlgcDgnsisExtrpyrmdlMvmntTyp | Type of pathologic diagnosis or feature which is assessed for its relationship to the participant's/subject's extrapyrimidal movement disorders | Type of pathologic diagnosis or feature which is assessed for its relationship to the participant's/subject's extrapyrimidal movement disorders | What are the primary and contributing pathologic diagnoses or features which you judge to be responsible for the subject's extrapyramidal movement disorders, if present? | No significant pathology;AD pathology present but insufficient for AD diagnosis;Alzheimer disease (AD);Lewy body disease;Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;FTLD-TDP;FTLD-Taupathies;Hydrocephalus;Prion-associated disease;Huntington's disease (HD);Neurodegeneration with brain iron accumulation;Vascular Parkinsonism;Idiopathic nigral degeneration;Hippocampal sclerosis;Other, specify | No significant pathology;AD pathology present but insufficient for AD diagnosis;Alzheimer disease (AD);Lewy body disease;Multiple system atrophy;Progressive supranuclear palsy;Corticobasal degeneration;FTLD-TDP;FTLD-Taupathies;Hydrocephalus;Prion-associated disease;Huntington's disease (HD);Neurodegeneration with brain iron accumulation;Vascular Parkinsonism;Idiopathic nigral degeneration;Hippocampal sclerosis;Other, specify | Alphanumeric |
Code the primary diagnoses or features with a 1. Code the contributing diagnoses or features with a 2. |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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| C00035 | Gender type | GenderTyp | Self-reported gender of the participant/subject. | Self-reported gender of the participant/subject.. | Gender | Alphanumeric |
Choose one. Response is obtained by report of the participant/subject or caretaker. |
The NIH Guidelines on Inclusion of Women and Minorities as Subjects in Clinical Research: The Office of Management and Budget (OMB) Directive No. 15 - http://grants.nih.gov/grants/funding/women_min/women_min.htm | Adult;Pediatric | Core | 3.00 | 2013-08-28 16:08:00.453 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
2200604 | |||||||||
| C08189 | Lewy related pathology severity scale | LewyReltPathlgySevrtyScale | Severity of the density of "Lewy related pathology" by region | Severity of the density of "Lewy related pathology" by region | None, Mild, Moderate, Severe, Not assessed, Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | None;Mild;Moderate;Severe;Not assessed;Unknown | Alphanumeric |
No instructions available |
BEACH, T. G., WHITE, C. L., HAMILTON, R. L., DUDA, J. E., IWATSUBO, T., DICKSON, D. W., LEVERENZ, J. B., RONCAROLI, F., BUTTINI, M., HLADIK, C. L., SUE, L. I., NOORIGIAN, J. V. & ADLER, C. H. 2008. Evaluation of alpha-synuclein immunohistochemical methods used by invited experts. Acta Neuropathol, 116, 277-88. ALAFUZOFF, I., PARKKINEN, L., AL-SARRAJ, S., ARZBERGER, T., BELL, J., BODI, I., BOGDANOVIC, N., BUDKA, H., FERRER, I., GELPI, E., GENTLEMAN, S., GIACCONE, G., KAMPHORST, W., KING, A., KORKOLOPOULOU, P., KOVACS, G. G., LARIONOV, S., MEYRONET, D., MONORANU, C., MORRIS, J., PARCHI, P., PATSOURIS, E., ROGGENDORF, W., SEILHEAN, D., STREICHENBERGER, N., THAL, D. R. & KRETZSCHMAR, H. 2008. Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol, 67, 125-43. | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18741 | Other pathology ischemic vascular disease specify text | OthrPathlgyIschmcVasclrDisST | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | The free-text field related to 'Other pathology ischemic vascular disease indicator'. Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | Other, specify | Alphanumeric |
Only answered if Question 23 (Is ischemic, hemorrhagic or vascular pathology present?) was answered YES |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
