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NINDS CDE Notice of Copyright
Addenbrooke’s Cognitive Examination-III (ACE-III)
Availability
This instrument is not currently available on the NINDS CDE website; however, copyright permission has been granted. A copy of the instrument can be obtained from: Neuroscience Research Australia
Classification
Supplemental: Parkinson’s Disease (PD)
Short Description of Instrument
Construct measured: global cognitive function (specific on 5 domains: attention and orientation, memory, verbal fluency, language and visuospatial skills).
Generic vs. disease specific: Generic.
Means of administration: Examiner administered, six pages, requiring pen and paper.
Intended respondent (e.g., patient, caregiver, etc.): Patient.
Scoring
Scoring: 18 points attention and orientation; 26 points memory; 14 points verbal fluency; 26 points language; 16 points visuospatial skills. Maximum = 100. Higher = better cognition. Scoring and administration guidelines can be accessed at: Neuroscience Research Australia
Comments/Special Instructions
N/A
References
Hsieh, S., McGrory, S., Leslie, F., Dawson, K., Ahmed, S., Butler, C. R., . . . Hodges, J. R. (2015). The Mini Addenbrooke's Cognitive Examination: a new assessment tool for dementia. Dement Geriatr Cogn Disord, 39(1-2), 1–11
 
Hsieh, S., Schubert, S., Hoon, C., Mioshi, E., & Hodges, J. R. (2013). Validation of the Addenbrooke's Cognitive Examination III in frontotemporal dementia and Alzheimer's disease. Dement Geriatr Cogn Disord, 36(3-4), 242–250.
 
Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology, 55(11), 1613–1620.
 
Matias-Guiu, J. A., Fernandez de Bobadilla, R., Escudero, G., Perez-Perez, J., Cortes, A., Morenas-Rodriguez, E., . . . Matias-Guiu, J. (2014). Validation of the Spanish version of Addenbrooke's Cognitive Examination III for diagnosing dementia. Neurologia, Jul 4. pii: S0213-4853(14), 130–133.
 
Reyes, M. A., Perez-Lloret, S., Roldan Gerschcovich, E., Martin, M. E., Leiguarda, R., & Merello, M. (2009). Addenbrooke's Cognitive Examination validation in Parkinson's disease. Eur J Neurol, 16(1), 142–147.
 
Velayudhan, L., Ryu, S. H., Raczek, M., Philpot, M., Lindesay, J., Critchfield, M., & Livingston, G. (2014). Review of brief cognitive tests for patients with suspected dementia. Int Psychogeriatr, 26(8), 1247–1262.
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