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University of Pennsylvania Smell Identification Test (UPSIT)
Availability
Please visit this website for more information about the instrument: http://sensonics.com/smell-identification-test-international-versions-available.html.
Classification
Supplemental for Parkinson's Disease (PD)
Short Description of Instrument
The Smell Identification Test (UPSIT) is a self-administered 40-item questionnaire. This test was developed over 25 years ago and has been used extensively in studies of olfactory dysfunction in diverse populations. It has been employed in numerous studies of PD patients. More recent modifications of this test have been developed, with fewer test items, but this test remains the standard test practical for evaluating olfaction in large groups of patients.
 
The test uses strips of paper impregnated with microencapsulated odors that are released upon scratching the strip with a pencil. The patient is given four choices from which to choose the correct odor. Forty different odors are presented in this test.
References
Bohnen NI, Gedela S, Herath P, Constantine GM, Moore RY. Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity. Neurosci Lett 2008;447:12-16.
 
Doty RL, Bromley SM, Stern MB. Olfactory testing as an aid in the diagnosis of Parkinson’s disease: development of optimal discrimination criteria.
Neurodegeneration 1995;4:93-97.
 
Doty RL, Shaman P, Kimmelman CP, Dann MS. University of Pennsylvania Smell identification Test: a rapid quantitative olfactory function test for the clinic. Laryngoscope 1984;94:176-178.
 
Hawkes CH, Shephard BC, Daniel SE. Olfactory dysfunction in Parkinson’s disease. J Neurol Neurosurg Psychiatry 1997;62:436-446.
 
Silveira-Moriyama L, Petrie A, Williams DR, et al. The use of a color coded probability scale to interpret smell tests in suspected parkinsonism. Mov Disord 2009;24:1144- 1153.
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