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CDE Detailed Report
This report contains detailed information about the selected CDEs.
Note: If at least one CDE was selected from a copyright- or trademark-protected instrument/scale then all of the CDEs from that instrument/scale are included in this report.
Disease: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Sub-Domain: History of Disease/Injury Event
CRF: Neuroendocrine/Hypothalamic Symptoms
Item count: 46 (46 distinct CDEs)
CDE ID
CDE Name
Variable Name
Definition / Description
Question Text
Permissible Value
Description
Data Type
Instructions
References
Population
Classification (e.g., Core)
Version #
Version Date
Aliases for Variable Name
CRF Module / Guideline
© or TM
Sub-Domain
Domain
Previous Title
Size
Input Restrictions
Min Value
Max Value
Measurement Type
LOINC ID
SNOMED
caDSR ID
CDISC ID
C17402
Site name
SiteName
The name of the site for the study
Site name
  
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
3.0
6/21/2013
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
Site name
255
Free-Form Entry
       
C19247
Subject ID
SubIDNam
Subject identification ID
Subject ID
  
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
6/5/2014
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
 
255
Free-Form Entry
       
C57194
Subnormal body temperature indicator
SubBodyTempInd
The indicator relating to whether the subject has a subnormal body temperature.
Subnormal body temperature
Yes;No;
Yes;No;
Alphanumeric
Data looking at body temperature vary substantially in terms of conclusions regarding average body temperatures or what constitutes normal versus abnormal temperatures. It is suggested that it would be reasonable to mark “yes” if a participant tends, on measurements on different occasions, to exhibit oral temperatures less than 97.0 F (36.1 C). It is recommended that participants avoid drinking or eating hot or cold foods or fluids for at least fifteen minutes prior to temperature measurement.
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57195
Marked diurnal fluctuation temperature indicator
MarkDiuFlucTempInd
The indicator relating to whether the subject has marked diurnal fluctuations in which his/her measured temperatures vary significantly throughout the day.
Marked diurnal fluctuations: measured temperatures vary significantly through the day
Yes;No;
Yes;No;
Alphanumeric
The evidence for this appears to be very limited and is not
sufficient to support a definition of what constitutes marked diurnal variation. Further research is needed to validate this symptom and the appropriate threshold
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57196
Feel hot cold alternate indicator
FeelHotColdAltInd
The indicator relating to whether the subject has alternating feelings of hot and cold.
Alternating feelings of hot and cold (or, one part of the body feels hot while another feels cold)?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57197
Feel hot cold alternate severity status
FeelHotColdAltSevStat
The status of the severity of the subject's alternating feelings of hot and cold.
If yes, indicate severity:
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57198
Feel hot cold alternate frequency type
FeelHotColdAltFreqTyp
The type of frequency that the subject is experiencing alternating feelings of hot and cold.
If yes, indicate frequency:
Daily;Monthly;Occasionally;
Daily;Monthly;Occasionally;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57199
Recurrent fever feeling indicator
RecurFevFeelInd
The indicator relating to whether the subject has recurrent feelings of feverishness.
Recurrent feelings of feverishness?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57200
Cold limb indicator
ColdLimbInd
The indicator relating to whether the subject has cold limbs (arms/legs/hands/feet).
Cold limbs (arms/legs/hands/feet)?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57201
Abnormal sweating episode indicator
AbnSweatEpiInd
The indicator relating to whether the subject has abnormal sweating episodes.
Abnormal sweating episodes?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57202
Abnormal sweating episode severity status
AbnSweatEpiSevStat
The status of the severity of the subject's abnormal sweating episodes.
If yes, indicate severity:
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57203
Abnormal sweating episode frequency type
AbnSweatEpiFreqTyp
The type of frequency pertaining to the subject's abnormal sweating episodes.
If yes, indicate frequency:
Daily;Monthly;Occasionally;
Daily;Monthly;Occasionally;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57204
Significant heat intolerance indicator
SigHeatIntolInd
The indicator relating to whether the subject has a significant intolerance of heat.
Significant intolerance of heat?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57205
Significant heat intolerance severity status
SigHeatIntolSevStat
The status of the severity of the subject's intolerance to heat.
If yes, indicate severity
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57206
Significant cold intolerance indicator
SigColdIntolInd
The indicator relating to whether the subject has a significant intolerance of cold.
Significant intolerance to cold?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57207
Significant cold intolerance severity status
SigColdIntolSevStat
The status of the severity of the subject's intolerance to cold.
If yes, indicate severity:
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57208
Marked weight increase loss indicator
MarkWtIncLossInd
The indicator relating to whether the subject had a marked increase or loss in weight.
Marked weight increase or loss?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57209
Weight gain value
WtGainVal
The value of the amount of weight the subject gained.
If weight gain, indicate how much weight gain
  
Numeric Values
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Free-Form Entry
  
kilogram
    
C57210
Weight gain duration
WtGainDur
The time duration in which the subject experienced his/her marked weight gain.
Over what time period?
  
Numeric Values
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Free-Form Entry
       
C57211
Weight loss value
WtLossVal
The value of the amount of weight the subject lost.
If weight loss, indicate how much weight loss
  
Numeric Values
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Free-Form Entry
  
kilogram
    
C57212
Weight loss duration
WtLossDur
The time duration in which the subject experienced his/her marked weight loss.
Over what time period?
  
Numeric Values
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Free-Form Entry
       
C57213
Significant appetite loss indicator
SigAppLossInd
The indicator relating to whether the subject experienced significant appetite loss.
Significant loss of appetite?
Yes;No;
Yes;No;
Alphanumeric
do not mark yes if loss of appetite seems to be
due primarily to a gastrointestinal issue – ie, significant, ongoing nausea
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57214
Significant appetite loss severity status
SigAppLossSevStat
The status of the severity of the subject's significant appetite loss.
If yes, indicate severity:
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57215
Significant appetite gain indicator
SigAppGainInd
The indicator relating to whether the subject experienced significant appetite gain.
Significant gain of appetite?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57216
Significant appetite gain severity status
SigAppGainSevStat
The status of the severity of the subject's significant appetite gain.
If yes, indicate severity:
Mild;Moderate;Severe;
Mild;Moderate;Severe;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
C57217
Illness symptom worsen stress indicator
IllSymptmWorsStressInd
The indicator relating to whether the subject's symptoms of illness worsen with stress.
Symptoms of illness worsen with stress?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
Carruthers BM et al. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition,
Diagnostic and Treatment Protocols. A Consensus Document. Journal of Chronic Fatigue Syndrome.
2003;11(1):7-115.

Hamilos DL, Nutter D, Gershtenson J, Redmond DP, Clementi JD, Schmaling KB, Make BJ, Jones JF. Core
body temperature is normal in chronic fatigue syndrome. Biol Psychiatry. 1998; 43(4):293-302.
Adult;Pediatric
Supplemental
1.0
1/3/2018
Aliases for variable name not defined
Neuroendocrine/Hypothalamic Symptoms
History of Disease/Injury Event
Disease/Injury Related Events
  
Single Pre-Defined Value Selected
       
07-19-2019
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