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CDE Detailed Report
This report contains detailed information about the selected CDEs.
Note: If at least one CDE was selected from a copyright- or trademark-protected instrument/scale then all of the CDEs from that instrument/scale are included in this report.
Disease:
Sub-Domain: Laboratory Tests and Biospecimens/Biomarkers
CRF: Peripheral Nerves - Biopsies and Autopsies
Item count: 28 (28 distinct CDEs)
CDE ID
CDE Name
Variable Name
Definition / Description
Question Text
Permissible Value
Description
Data Type
Instructions
References
Population
Classification (e.g., Core)
Version #
Version Date
Aliases for Variable Name
CRF Module / Guideline
© or TM
Sub-Domain
Domain
Previous Title
Size
Input Restrictions
Min Value
Max Value
Measurement Type
LOINC ID
SNOMED
caDSR ID
CDISC ID
C12226
Specimen source type
SpecmnSourcTyp
Type of specimen collection source
Specimen type?
Biopsy;Autopsy;
Biopsy;Autopsy;
Alphanumeric
Supplemental - Highly Recommended
No references available
Adult;Pediatric
Supplemental–Highly Recommended
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Specimen source type
 
Single Pre-Defined Value Selected
       
C12227
Postmortem interval for autopsy specimen value
PstmrtmIntrvlApSpecmnVal
Interval in hours of time elapsed between death and the autopsy at which the tissue specimen was collected
If this is an autopsy specimen, what is the approximate postmortem interval?
  
Numeric Values
Only answered if "Autopsy" is answered for "Is this a biopsy or autopsy specimen?"
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Postmortem interval for autopsy specimen value
 
Free-Form Entry
  
hour
    
C12230
Tissue specimen collection date and time
TissSpecmnCollctnDateTime
Date (and time if applicable and known) when the tissue specimen was collected
Date of tissue collection
  
Date or Date & Time
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).
No references available
Adult;Pediatric
Core
3.0
7/25/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Tissue specimen collection date and time
 
Free-Form Entry
       
C12277
Biospecimen fragment collect count
BiospecmnFragCollctCt
Count of fragments collected in the tissue specimen
Number of fragments collected
  
Numeric Values
No instructions available
No references available
Adult;Pediatric
Core
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy number of fragments collected
 
Free-Form Entry
       
C12229
Tissue specimen size measurement
TissSpecmnSizeMeasr
Measurement of the size of the tissue specimen collected
Size of fragments
  
Numeric Values
Answer should be recorded as a dimension (AAxAAxAA) in centimeters (cm).
No references available
Adult;Pediatric
Core
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Tissue specimen measurement
 
Free-Form Entry
  
centimeter
    
C12231
Laboratory name
LabName
Name of laboratory where assessment was performed
Name of Laboratory where pathology was performed
  
Alphanumeric
Record the laboratory name where pathology was performed
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Laboratory name
255
Free-Form Entry
       
C12232
Laboratory director name
LabDirectorName
Name of laboratory director where assessment was performed
Name of Laboratory Director
  
Alphanumeric
No instructions available
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Laboratory director name
255
Free-Form Entry
       
C12233
Preservation technique used type
PresrvtnTechnqUseTyp
Type of preservation technique used to preserve the specimen
Processing?
Frozen;Formalin-fixed/ Paraffin-embedded;Glutaraldehyde-fixed/ Epon-embedded;Glutaraldehyde-fixed/ Teased fibers;
Frozen;Formalin-fixed/ Paraffin-embedded;Glutaraldehyde-fixed/ Epon-embedded;Glutaraldehyde-fixed/ Teased fibers;
Alphanumeric
Choose only one
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Preservation technique used type
 
Single Pre-Defined Value Selected
       
C12234
Preservation technique used amount value
PresrvtnTechnqUseAmntVal
Value of the amount of preservation solution or material used to preserve the specimen
Amount
  
Alphanumeric
Answer for the freezing or fixation technique used. Answer should be recorded in milligrams (mg). If amount used is not known, select Not known.
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Preservation technique used amount value
255
Free-Form Entry
  
milligram
    
C12239
Electron microscopy performed indicator
ElectrnMicroPerfInd
Indicator of whether electron microscopy was performed
Was electron microscopy performed?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Electron microscopy performed indicator
 
Single Pre-Defined Value Selected
       
C12240
Biochemical or genetic test performed indicator
BiochemGenTestPerfInd
Indicator of whether subsequent biochemical or genetic testing was performed
Was subsequent biochemical or genetic testing performed?
Yes;No;
Yes;No;
Alphanumeric
No instructions available
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biochemical or genetic test performed indicator
 
Single Pre-Defined Value Selected
       
C12241
Biochemical or genetic test name
BiochemGenTestName
Name of the biochemical or genetic test as performed on the specimen
Test name
  
Alphanumeric
No instructions available
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biochemical or genetic test type
255
Free-Form Entry
       
C12242
Biochemical or genetic test result value
BiochemGenTestResltVal
Results of the biochemical or genetic test performed on the specimen
Results (including units)
  
Alphanumeric
Only answered if "Yes" is answered for "Was subsequent biochemical or genetic testing performed?" Include units with results, if applicable.
No references available
Adult;Pediatric
Supplemental
3.0
7/25/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biochemical or genetic test result
255
Free-Form Entry
       
C12235
Histochemical stains used type
HistchmclStainUseTyp
Type of standard histochemical stains used on the tissue specimen
Which standard histochemical stains were used?
H and E;Masson trichrome;Congo red;Myelin stain, specify;Microorganism stains, specify;
H and E;Masson trichrome;Congo red;Myelin stain, specify;Microorganism stains, specify;
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens ֠Choose all that apply.
Supplemental - Highly Recommended
No references available
Adult;Pediatric
Supplemental–Highly Recommended
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Histochemical stains used type
 
Multiple Pre-Defined Values Selected
       
C18828
Histochemical stains used other text
HistchmclStainUseOTH
The free-text field related to 'Histochemical stains used type' specifying other text. Type of standard histochemical stains used on the tissue specimen
Other, specify
  
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens ֠Choose all that apply.
Supplemental - Highly Recommended
No references available
Adult;Pediatric
Supplemental–Highly Recommended
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
 
4000
Free-Form Entry
       
C12278
Specimen histochemical stain diagnostic abnormality type
SpcmnHistStainDiagnsAbnrmlyTyp
Types of diagnostic abnormalities noted on the histochemical stains performed on the tissue specimen
Which of the following abnormalities were noted on histochemical stains?
Decreased fiber density;Decreased myelination;Atherosclerosis;Amyloid deposits;Myelin ovoids;Abnormal storage material;Granulomas;Microorganisms;Thrombi in blood vessels;Lymphatic inflammation;Vasculitis;
Decreased fiber density;Decreased myelination;Atherosclerosis;Amyloid deposits;Myelin ovoids;Abnormal storage material;Granulomas;Microorganisms;Thrombi in blood vessels;Lymphatic inflammation;Vasculitis;
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens ֠Choose all that apply and provide details below.
No references available
Adult;Pediatric
Core
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy diagnostic abnormalities present on histochemical stains
 
Multiple Pre-Defined Values Selected
       
C17907
Specimen histochemical stain diagnostic abnormality text
SpcmnHistStainDiagnsAbnrmlyTxt
Text description of details of the specified diagnostic abnormalities on the histochemical stains
Details of diagnostic abnormalities
  
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
 
255
Free-Form Entry
       
C17906
Specimen immunohistochemical stain use indicator
SpecmnImmhistchmclStainUseInd
Indicator whether immunohistochemcial stains were used on the tissue specimen
If immunohistochemical stains were used, record results in below table
N/A;
N/A;
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
  
Single Pre-Defined Value Selected
       
C12279
Specimen immunohistochemical stain name
SpecmnImmhistchmclStainNam
Name of immunohistochemical stain used on tissue specimen
Stain Used
  
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy immunohistochemical stain name
255
Free-Form Entry
       
C12280
Specimen immunohistochemical stain result
SpecmnImmhistchmclStainReslt
Result of immunohistochemical stain performed
Results
  
Alphanumeric
Histological Findings in Nerve Biopsy or Autopsy specimens
No references available
Adult;Pediatric
Supplemental
3.0
7/25/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy immunohistochemical stain result
255
Free-Form Entry
       
C12243
Microscopy epon embedded tissue abnormality type
MicscpyEponEmbedTissAbnrmlyTyp
Type of microscopy employed to view abnormalities in epon-embedded tissue specimen
Abnormalities seen on
Light microscopy (Toluidine blue staining);Electron microscopy;Both - light microscopy and electron microscopy;
Light microscopy (Toluidine blue staining);Electron microscopy;Both - light microscopy and electron microscopy;
Alphanumeric
Epon-Embedded Tissue/Electron Microscopy (Nerve Biopsy/Autopsy Specimens)
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Epon embedded tissue abnormalities microscopy type
 
Single Pre-Defined Value Selected
       
C12238
Biopsy and autopsy epon embedded tissue abnormalities location type
BpApEponEmbedTissAbnrmlLocTyp
Type of abnormality observed microscopically in epon-embedded tissue specimen
Abnormalities noted in
Myelinated axon number, specify;Myelinated axon clusters, possibly regenerative;Axonal degeneration;Myelination, specify;Mitochondria, specify;Abnormal storage material, specify;
Myelinated axon number, specify;Myelinated axon clusters, possibly regenerative;Axonal degeneration (active);Myelination, specify;Mitochondria, specify;Abnormal storage material, specify;
Alphanumeric
Epon-Embedded Tissue/Electron Microscopy (Nerve Biopsy/Autopsy Specimens)
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy and Autopsy epon embedded tissue abnormalities location type
 
Multiple Pre-Defined Values Selected
       
C12281
Tissue abnormality myelin axon decrease status
TissAbnrmlyMyelnAxnDecreasStat
Status of any observed decrease in the myelinated axon numbers of the epon-embedded tissue specimen
Myelinated axon number, specify
Mild decrease;Severe decrease;
Mild decrease;Severe decrease;
Alphanumeric
Epon-Embedded Tissue/Electron Microscopy (Nerve Biopsy/Autopsy Specimens)
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy myelinated axon severity result
 
Single Pre-Defined Value Selected
       
C12282
Tissue abnormality myelination type
TissAbnrmlyMyelinationTyp
Type of any observed myelination in the epon-embedded tissue specimen
Myelination, specify
Abnormally thin myelin;Myelin absent from large diameter axons;Abnormal myelin architecture;Onion bulbs;Segmental demyelination/remyelination in excess of age related change;Bands of Bungner;
Abnormally thin myelin;Myelin absent from large diameter axons;Abnormal myelin architecture;Onion bulbs;Segmental demyelination/remyelination in excess of age related change (teased fiber preparation);Bands of Bungner (empty Schwann cells);
Alphanumeric
Epon-Embedded Tissue/Electron Microscopy (Nerve Biopsy/Autopsy Specimens)
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy myelination abnormality type
 
Multiple Pre-Defined Values Selected
       
C12283
Tissue abnormality mitochondria type
TissAbnrmlyMitochondTyp
Type of any mitochondrial abnormality observed in the epon-embedded tissue specimen
Mitochondria, specify
Abnormal shape;Abnormal location, specify;Abnormal numbers;Abnormal architecture;
Abnormal shape;Abnormal location, specify;Abnormal numbers;Abnormal architecture;
Alphanumeric
Epon-Embedded Tissue/Electron Microscopy (Nerve Biopsy/Autopsy Specimens)
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
Biopsy mitochondria abnormality type
 
Multiple Pre-Defined Values Selected
       
C17905
Biopsy and autopsy abnormal storage material text
BpApAbnrmlStrgMatTxt
Text describing biopsy or autopsy material that has been stored abnormally
Abnormal storage material, specify
  
Alphanumeric
No instructions available
No references available
Adult;Pediatric
Supplemental
3.0
7/24/2013
Aliases for variable name not defined
Peripheral Nerves - Biopsies and Autopsies
Laboratory Tests and Biospecimens/Biomarkers
Assessments and Examinations
 
255
Free-Form Entry
       
12-17-2018
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